The DOI matches its Crossref record.
Subcellular localization of pulmonary antiotensin-converting enzyme (kininase II)
Open accessAbstract
Goat antibodies to pig lung angiotensin-converting enzyme (kininase II) were conjugated to microperoxidase. Rat lung tissue, previously incubated with non-immune goat serum, was incubated with the antibody-microperoxidase conjugate and then with H2O2 and 3,3-diaminobenzidine. Electron microscopy revealed reaction product on the plasma membrane and caveolae of endothelial cells, especially those of capillaries and venules. These results support the hypothesis that angiotensin I and bradykinin are metabolized by enzymes on the luminal surface of pulmonary endothelial cells.
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Cited by
Bernstein, K. E., Ong, F. S., Blackwell, W.-L. B., Shah, K. H., Giani, J. F., Gonzalez-Villalobos, R. A., Shen, X. Z., & Fuchs, S. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.006809 · Cited by 324
Biomarkers: A potential prognostic tool for silicosis
Pandey, J., & Agarwal, D. (2012) · Indian Journal of Occupational and Environmental Medicine · doi:10.4103/0019-5278.111746 · Cited by 47
Metadata
- Authors
- Ryan, J. W., Ryan, U. S., Schultz, D. R., Whitaker, C., Chung, A., & Dorer, F. E.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1975-02-15
- Volume
- 146
- Issue
- 2
- Pages
- 497-499
- ISSN
- 0306-3283 (ISSN-L)
- OpenAlex
- W1466908809
- Cited by
- 295
- References
- 0
- FWCI
- 11.21
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Subcellular localization of pulmonary antiotensin-converting enzyme (kininase II). https://app.cochat.ai/papers/10.1042/bj1460497
- The paper
- Ryan, J. W., Ryan, U. S., Schultz, D. R., Whitaker, C., Chung, A., & Dorer, F. E. (1975). Subcellular localization of pulmonary antiotensin-converting enzyme (kininase II). Biochemical Journal. https://doi.org/10.1042/bj1460497
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
