The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Novel inhibitors of poly(ADP-ribose) synthetase
Open accessAbstract
In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. Two of the benzamides, 3-aminobenzamide and 3-methoxybenzamide, were found to be competitive inhibitors, with Ki values or less than 2 microM.
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Cites
A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250
Sedmak, J. J., & Grossberg, S. E. (1977) · Analytical Biochemistry · doi:10.1016/0003-2697(77)90428-6 · Cited by 3,030
Poly (ADP-Ribose) and ADP-Ribosylation of Proteins
Hayaishi, O., & Veda, K. (1977) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.46.070177.000523 · Cited by 585
Poly(ADP-ribose) and ADP-ribosylation of proteins
Hilz, H., & Stone, P. (1976) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/bfb0027686 · Cited by 286
Specific inhibition of poly adpribose polymerase by thymidine and nicotinamide in HeLa cells
Preiss, J., SCHLAEGER, R., & Hilz, H. (1971) · FEBS Letters · doi:10.1016/0014-5793(71)80524-0 · Cited by 139
Clark, J. B., Ferris, G., & Pinder, S. (1971) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(71)90012-8 · Cited by 124
Cited by
Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain
Guo, J. U., Su, Y., Zhong, C., Ming, G.-L., & Song, H. (2011) · Cell · doi:10.1016/j.cell.2011.03.022 · Cited by 1,360
Tankyrase, a Poly(ADP-Ribose) Polymerase at Human Telomeres
Smith, S., Giriat, I., Schmitt, A., & de Lange, T. (1998) · Science · doi:10.1126/science.282.5393.1484 · Cited by 1,012
PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance
Rose, M., Burgess, J. T., O’Byrne, K., Richard, D. J., & Bolderson, E. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.564601 · Cited by 719
PARP and PARG inhibitors in cancer treatment
Slade, D. (2020) · Genes & Development · doi:10.1101/gad.334516.119 · Cited by 667
Regulated necrosis: disease relevance and therapeutic opportunities
Conrad, M., Angeli, J. P. F., Vandenabeele, P., & Stockwell, B. R. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2015.6 · Cited by 630
Metadata
- Authors
- Purnell, M. R., & Whish, W. J.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1980-03-01
- Volume
- 185
- Issue
- 3
- Pages
- 775-777
- ISSN
- 0264-6021 (ISSN-L)
- OpenAlex
- W2325814368
- Cited by
- 527
- References
- 5
- FWCI
- 14.03
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Purnell, M. R., & Whish, W. J. (1980). Novel inhibitors of poly(ADP-ribose) synthetase. Biochemical Journal. https://doi.org/10.1042/bj1850775
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
