Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
POWELL, Darren J., TURBAN, Sophie, GRAY, Alexander, HAJDUCH, Eric, HUNDAL, Harinder S.·2004·Biochemical Journal
Cited by (267)
Items 101–200 of 267
- Niacin: a re‐emerging pharmaceutical for the treatment of dyslipidaemiaHelen Vosper · 2009 · British Journal of Pharmacology
- Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASERima Hage Hassan, Ana Catarina Pacheco de Sousa, Rana Mahfouz, Isabelle Hainault, Agnieszka Urszula Błachnio-Zabielska, Olivier Bourron, Fabien Koskas, J Górski, Pascal Ferré, Fabienne Foufelle et al. · 2016 · Journal of Biological Chemistry
- Dietary interventions for metabolic syndrome: Role of modifying dietary fatsCraig Lawrence Kien · 2009 · Current Diabetes Reports
- Fatty acid‐induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipidSabin, Matthew A., Stewart, Claire E.H., Crowne, Elizabeth C., Turner, Stephen J., Hunt, Linda P., Welsh, Gavin I., Grohmann, Malcolm J., Holly, Jeff M.P., Shield, Julian P.H. · 2007 · Journal of Cellular Physiology
- Oleate protects against palmitate-induced insulin resistance in L6 myotubesDan Gao, Helen R. Griffiths, Clifford J. Bailey · 2009 · British Journal Of Nutrition
- Contribution of mitochondria and endoplasmic reticulum dysfunction in insulin resistance: Distinct or interrelated roles?Jennifer Rieusset · 2015 · Diabetes & Metabolism
- Sphingolipid Metabolism and Obesity-Induced InflammationSe Chan Kang, Bo-Rahm Kim, Su‐Yeon Lee, Tae‐Sik Park · 2013 · Frontiers in Endocrinology
- Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics WorkflowAtul S. Deshmukh, Jüergen Cox, Lars Juhl Jensen, Felix Meissner, Matthias Mann · 2015 · Journal of Proteome Research
- The Proposal of Molecular Mechanisms of Weak Organic Acids Intake-Induced Improvement of Insulin Resistance in Diabetes Mellitus via Elevation of Interstitial Fluid pHYoshinori Marunaka · 2018 · International Journal of Molecular Sciences
- A comparative analysis of various flavonoids in the regulation of obesity and diabetes: An in vitro and in vivo studyRitu Varshney, Rutusmita Mishra, Neeladrisingha Das, Debabrata Sircar, Partha Roy · 2019 · Journal of Functional Foods
- The Saga of Endocrine FGFsPhuc Phan, Bibhuti Ballav Saikia, Shivakumar Sonnaila, Shilpi Agrawal, Zeina Alraawi, Thallapuranam Krishnaswamy Suresh Kumar, Shilpa Iyer · 2021 · Cells
- Plasma Ceramide Species Are Associated with Diabetes Risk in Participants of the Strong Heart StudyAmanda M. Fretts, Paul N. Jensen, Andrew N. Hoofnagle, Barbara McKnight, Barbara V. Howard, Jason G. Umans, Chaoyu Yu, Colleen M. Sitlani, David S. Siscovick, Irena B. King et al. · 2019 · Journal of Nutrition
- Regulation and dysregulation of glucose transport in cardiomyocytesChristophe Montessuit, Rene A. Lerch · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cellsKeisuke Sawada, Kyuichi Kawabata, Takatoshi Yamashita, Kengo Kawasaki, Norio Yamamoto, Hitoshi Ashida · 2012 · Lipids in Health and Disease
- New Evidence for the Role of Ceramide in the Development of Hepatic Insulin ResistanceKarolina Konstantynowicz-Nowicka, Ewa Harasim‐Symbor, Marcin Baranowski, Adrian Chabowski · 2015 · PLoS ONE
- Short‐Term Effects of Dietary Fatty Acids on Muscle Lipid Composition and Serum Acylcarnitine Profile in Human SubjectsCraig Lawrence Kien, Karen Everingham, Robert D. Stevens, Naomi K. Fukagawa, Deborah M. Muoio · 2010 · Obesity
- Ceramides in Adipose TissueYing Li, Chad Lamar Talbot, Bhagirath Chaurasia · 2020 · Frontiers in Endocrinology
- Glycosphingolipids and Insulin ResistanceJohannes M. F. G. Aerts, Rolf G. Boot, Marco van Eijk, J.E.M. Groener, Nora Bijl, Elisa Lombardo, Florence Biétrix, Nick Dekker, Albert Kornelis Groen, Roelof Ottenhoff et al. · 2011 · Advances in experimental medicine and biology
- Skeletal muscle atrophy and dysfunction in obesity and type-2 diabetes mellitus: Myocellular mechanisms involvedÍñigo M. Pérez Castillo, Josep María Adell Argilés, Ricardo Rueda, María Ramírez, Jose Maria Lopez Pedrosa · 2025 · Reviews in Endocrine and Metabolic Disorders
- Divergent Role of Sphingosine 1-Phosphate on Insulin ResistanceSusann Fayyaz, Lukasz Japtok, Burkhard Kleuser · 2014 · Cellular Physiology and Biochemistry
- Skeletal muscle insulin resistance induced by adipocyte-conditioned medium: underlying mechanisms and reversibilityHenrike Sell, Kristin Eckardt, Annika Taube, Daniel Tews, Mihaela Gurgui, Gerhild van Echten‐Deckert, Jürgen Eckel · 2008 · American Journal of Physiology-Endocrinology and Metabolism
- Adipose Tissue and Ceramide Biosynthesis in the Pathogenesis of ObesityFahumiya Samad, Leylla Badeanlou, Charmi Shah, Guang Yang · 2011 · Advances in experimental medicine and biology
- Lipid mediators of liver injury in nonalcoholic fatty liver diseaseSuthat Liangpunsakul, Naga Chalasani · 2018 · American Journal of Physiology-Gastrointestinal and Liver Physiology
- MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intoleranceOh Sung Kwon, Ruth Tanner, Katherine M. Barrows, Marah C. Runtsch, J. David Symons, Thunder Jalili, Benjamin T. Bikman, Donald A. McClain, Ryan M. O’Connell, Micah John Drummond · 2015 · American Journal of Physiology-Endocrinology and Metabolism
- Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: The effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acidsYan Y. Lam, George Hatzinikolas, Jacquelyn M. Weir, Alena Janovská, Andrew J. McAinch, Philip A. Game, Peter J. Meikle, Gary Wittert · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Ganglioside GM3 as a gatekeeper of obesity‐associated insulin resistance: Evidence and mechanismsChristopher Lipina, Harinder S. Hundal · 2015 · FEBS Letters
- Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide ProductionThi Thu Trang Tran, Bárbara Graziela Postal, Sylvie Demignot, Agnès Ribeiro, Céline Osinski, Jean-Paul Paı̈s de Barros, Agnieszka Urszula Błachnio-Zabielska, Armelle Leturque, Monique Rousset, Pascal Ferré et al. · 2016 · Journal of Biological Chemistry
- Ceramides are fuel gauges on the drive to cardiometabolic diseaseJoseph L. Wilkerson, Sean M. Tatum, William L. Holland, Scott A. Summers · 2024 · Physiological Reviews
- Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal MuscleSilvie Timmers, Johan de Vogel‐van den Bosch, Matthijs K. C. Hesselink, Denis van Beurden, Gert Schaart, Maria J. Ferraz, Mario H. Losen, Pilar Martínez‐Martínez, Marc H. De Baets, Johannes M. F. G. Aerts et al. · 2011 · PLoS ONE
- Sphingolipids in obesity and related complicationsPin-Lan Li · 2016 · Frontiers in bioscience
- Fibroblast growth factor-21 potentiates glucose transport in skeletal muscle fibersGiovanni Rosales‐Soto, Alexis Díaz‐Vegas, Mariana Casas, Ariel Eduardo Contreras‐Ferrat, Enrique Jaimovich · 2020 · Journal of Molecular Endocrinology
- Berberine improves free-fatty-acid–induced insulin resistance in L6 myotubes through inhibiting peroxisome proliferator–activated receptor γ and fatty acid transferase expressionsYanfeng Chen, Ying Li, Yanwen Wang, Ying Wen, Changhao Sun · 2009 · Metabolism
- Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse modelCristina Martínez-García, Adriana Izquierdo, Vidya Velagapudi, Yurena Vivas, Ismael Velasco, Mark Campbell, Keith Burling, Fernando Cava, Manuel Ros, Matej Orešič et al. · 2012 · Disease Models & Mechanisms
- Growth hormone‐induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activityBirgitte Nellemann, Mikkel Holm Vendelbo, Thomas S. Nielsen, Ann Mosegaard Bak, Morten Lyng Høgild, Steen B. Pedersen, Rasmus Sjørup Biensø, Henriette Pilegaard, Niels Møller, Niels Jessen et al. · 2013 · Acta Physiologica
- Divergent Role of Sphingosine 1-Phosphate in Liver Health and DiseaseBurkhard Kleuser · 2018 · International Journal of Molecular Sciences
- Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesityJenny Lee, Ya Xu, Li Lu, Bryan C. Bergman, J. Wayne Leitner, Clifford R. Greyson, Boris Draznin, Gregory G. Schwartz · 2009 · American Journal of Physiology-Heart and Circulatory Physiology
- Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistanceJennifer Rieusset, Marie‐Agnès Chauvin, Annie Durand, Amélie Bravard, Fabienne Laugerette, Marie‐Caroline Michalski, Hubert Vidal · 2011 · Biochemical and Biophysical Research Communications
- Short-Term Manipulation of Plasma Free Fatty Acids Does Not Change Skeletal Muscle Concentrations of Ceramide and Glucosylceramide in Lean and Overweight SubjectsMireille J. M. Serlie, Alfred J. Meijer, J.E.M. Groener, Marinus Durán, Erik Endert, Eric Fliers, Johannes M. F. G. Aerts, Hans P. Sauerwein · 2007 · The Journal of Clinical Endocrinology & Metabolism
- Rotten to the Cortex: Ceramide-Mediated Lipotoxicity in Diabetic Kidney DiseaseRebekah J. Nicholson, Marcus G. Pezzolesi, Scott A. Summers · 2021 · Frontiers in Endocrinology
- Defining the role of DAG, mitochondrial function, and lipid deposition in palmitate-induced proinflammatory signaling and its counter-modulation by palmitoleateMacrae, Katherine, Stretton, Clare, Lipina, Christopher, Blachnio-Zabielska, Agnieszka, Baranowski, Marcin, Gorski, Jan, Marley, Anna, Hundal, Harinder S. · 2013 · Journal of Lipid Research
- Red Blood Cell Fatty Acids and Incident Diabetes Mellitus in the Women’s Health Initiative Memory StudyWilliam Stephen Harris, Juhua Luo, James V. Pottala, Karen L. Margolis, Mark Andrew Espeland, Jennifer G. Robinson · 2016 · PLoS ONE
- Effect of metformin on bioactive lipid metabolism in insulin-resistant musclePiotr Zabielski, Marta Chacińska, Karol Charkiewicz, Marcin Baranowski, J Górski, Agnieszka Urszula Błachnio-Zabielska · 2017 · Journal of Endocrinology
- Ceramide and sphingosine 1-phosphate in adipose dysfunctionZijian Fang, Susan Pyne, Nigel J. Pyne · 2019 · Progress in Lipid Research
- A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbiditiesYun Pan, Jieying Li, Panjie Lin, Lihua Wan, Yiqian Qu, Lingyong Cao, Lei Wang · 2024 · Frontiers in Pharmacology
- Oleate-enriched diet improves insulin sensitivity and restores muscle protein synthesis in old ratsNicolas Tardif, Jérôme Salles, Jean‐François Landrier, Isabelle Mothe‐Satney, Christelle Guillet, Carole Vaysse, Lydie Combaret, Christophe Giraudet, Véronique Patrac, Justine Bertrand‐Michel et al. · 2011 · Clinical Nutrition
- Oleate prevents palmitate-induced atrophy via modulation of mitochondrial ROS production in skeletal myotubes.Lee, Hojun, Lim, Jae-Young, Choi, Seung-Jun · 2017 · Oxidative Medicine and Cellular Longevity
- Lipid imaging of human skeletal muscle using TOF‐SIMS with bismuth cluster ion as a primary ion sourceYlva Magnusson, Peter Friberg, Peter Sjövall, Frida Dangardt, Per Malmberg, Yun Chen · 2008 · Clinical Physiology and Functional Imaging
- Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscleHakam Hasan Alkhateeb, Arend Bonen · 2010 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Development and validation of LC-MS/MS method for determination of very long acyl chain (C22:0 and C24:0) ceramides in human plasmaHui Jiang, Fong‐Fu Hsu, Marsha S. Farmer, Linda R. Peterson, Jean E. Schaffer, Daniel S. Ory, Xuntian Jiang · 2013 · Analytical and Bioanalytical Chemistry
- Role of ceramide in apoptosis and development of insulin resistanceD. I. Kuzmenko, T. K. Klimenteva · 2016 · Biochemistry (Moscow)
- Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetesAmanda M. Fretts, Paul N. Jensen, Andrew N. Hoofnagle, Barbara McKnight, Barbara V. Howard, Jason G. Umans, Colleen M. Sitlani, David S. Siscovick, Irena B. King, Luc Djoussé et al. · 2021 · Journal of Lipid Research
- Palmitate and inflammatory state additively induce the expression of PTP1B in muscle cellsLeila Parvaneh, Reza Meshkani, Salar Bakhtiyari, Narges Mohammadtaghvaei, Sattar Gorgani‐Firuzjaee, Gholamreza Taheripak, Abolfazl Golestani, Mehdi Foruzandeh, Bagher A. Larijani, Mohammad Taghikhani · 2010 · Biochemical and Biophysical Research Communications
- Hot topic: Ceramide inhibits insulin sensitivity in primary bovine adipocytesJorge Eduardo Rico, W.A. Myers, David Laub, A.N. Davis, Q. Zeng, J.W. McFadden · 2018 · Journal of Dairy Science
- Paradoxical changes in muscle gene expression in insulin-resistant subjects after sustained reduction in plasma free fatty acid concentration.Bajaj, Mandeep, Medina-Navarro, Rafael, Suraamornkul, Swangjit, Meyer, Christian, DeFronzo, Ralph A., Mandarino, Lawrence J. · 2007 · Diabetes
- Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2Zhi-Qiang Chang, Su‐Yeon Lee, Hyejin Kim, Jung Ran Kim, Su Jung Kim, In‐Kyung Hong, Byung‐Chul Oh, Cheolsoo Choi, Ira J. Goldberg, Tae‐Sik Park · 2010 · Prostaglandins & Other Lipid Mediators
- The PPARδ agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cellsDimopoulos, Nikolaos, Watson, Maria, Green, Charlotte, Hundal, Harinder S. · 2007 · FEBS Letters
- Enhanced Insulin Sensitivity Associated with Provision of Mono and Polyunsaturated Fatty Acids in Skeletal Muscle Cells Involves Counter Modulation of PP2ANardi, Francesca, Lipina, Christopher, Magill, David, Hage Hassan, Rima, Hajduch, Eric, Gray, Alexander, Hundal, Harinder S. · 2014 · PLoS ONE
- Involvement of de novo ceramide synthesis in pro-inflammatory adipokine secretion and adipocyte–macrophage interactionYoji Hamada, Hiroshi Nagasaki, Atsushi Fujiya, Yusuke Seino, Qing-Long Shang, Takeshi Suzuki, Hiroyuki Hashimoto, Yutaka Oiso · 2014 · The Journal of Nutritional Biochemistry
- The Role of Sphingolipid Signaling in Oxidative Lung Injury and Pathogenesis of Bronchopulmonary DysplasiaJaya Mary Thomas, Tara Sudhadevi, Prathima Basa, Alison W. Ha, Viswanathan Natarajan, Anantha K. Harijith · 2022 · International Journal of Molecular Sciences
- Chronic Effects of Palmitate Overload on Nutrient-Induced Insulin Secretion and Autocrine Signalling in Pancreatic MIN6 Beta CellsMaria Watson, Katherine Macrae, Anna E. Marley, Harinder S. Hundal · 2011 · PLoS ONE
- Oleic Acid Stimulates Glucose Uptake Into Adipocytes by Enhancing Insulin Receptor SignalingAyako Tsuchiya, Hisao Nagaya, Takeshi Kanno, Tomoyuki Nishizaki · 2014 · Journal of Pharmacological Sciences
- Cellular depletion of atypical PKCλ is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cellsStretton, Clare, Evans, Ashleigh, Hundal, Harinder S. · 2010 · American Journal of Physiology-Endocrinology and Metabolism
- 5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubesHyun Jeong Kwak, Hye‐Eun Choi, Hyae Gyeong Cheon · 2017 · Scientific Reports
- Genetic determinants for intramuscular fat content and water-holding capacity in mice selected for high muscle massStefan Kärst, Riyan Cheng, Armin Otto Schmitt, Hyuna Yang, Fernando Pardo‐Manuel de Villena, Abraham A. Palmer, Gudrun A. Brockmann · 2011 · Mammalian Genome
- Modulation of cellular insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cellsDiana N. Obanda, William T. Cefalu · 2013 · The Journal of Nutritional Biochemistry
- Protein Kinase Cζ Attenuates Hypoxia-induced Proliferation of Fibroblasts by Regulating MAP Kinase Phosphatase-1 ExpressionMegan D. Short, Stephanie M. Fox, Ching F. Lam, Kurt R. Stenmark, Mita Das · 2006 · Molecular Biology of the Cell
- Effects of Inhibition of Serine Palmitoyltransferase (SPT) and Sphingosine Kinase 1 (SphK1) on Palmitate Induced Insulin Resistance in L6 MyotubesAgnieszka Mikłosz, B. Lukaszuk, M. Baranowski, J. Górski, A. Chabowski · 2013 · PLoS ONE
- A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscleSophie E. Hussey, Helen Lum, A. Villanueva Alvarez, Yolanda Cipriani, José de Jesús Garduño‐García, Luis Anaya, John J. Dubé, Nicolas Musi · 2013 · Diabetologia
- Inhibition of malonyl-CoA decarboxylase reduces the inflammatory response associated with insulin resistanceVictor Samokhvalov, John R. Ussher, Natasha Fillmore, Ian K. G. Armstrong, Wendy Keung, Daniel Moroz, David G. Lopaschuk, John M. Seubert, Gary D. Lopaschuk · 2012 · American Journal of Physiology-Endocrinology and Metabolism
- Intramyocellular fat storage in metabolic diseasesClaire Laurens, Cédric Moro · 2015 · Hormone Molecular Biology and Clinical Investigation
- Attenuation of Free Fatty Acid-Induced Muscle Insulin Resistance by Rosemary ExtractFilip Vlavcheski, Evangelia Tsiani · 2018 · Nutrients
- Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 miceZabielski, Piotr, Blachnio-Zabielska, Agnieszka, Lanza, Ian R., Gopala, Srinivas, Manjunatha, S., Jakaitis, Daniel R., Persson, Xuan-Mai, Gransee, Jaime, Klaus, Katherine A., Schimke, Jill M. et al. · 2014 · American Journal of Physiology-Endocrinology and Metabolism
- The twists and turns of sphingolipid pathway in glucose regulationGergana M. Deevska, Mariana Nikolova‐Karakashian · 2010 · Biochimie
- Carnosic Acid Attenuates the Free Fatty Acid-Induced Insulin Resistance in Muscle Cells and AdipocytesDanja J. Den Hartogh, Filip Vlavcheski, Adria Giacca, Rebecca E. K. MacPherson, Evangelia Tsiani · 2022 · Cells
- Myocardial Fatty Acid Metabolism and Lipotoxicity in the Setting of Insulin ResistanceBernard P. Kok, David N. Brindley · 2012 · Heart Failure Clinics
- Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosisYing Li, Chad Lamar Talbot, Bhawna Chandravanshi, Alec Ksiazek, Ayushi Sood, Kamrul Hasan Chowdhury, J. Alan Maschek, James Eric Cox, Adhini Kuppuswamy Satheesh Babu, Henry A. Paz et al. · 2022 · Scientific Reports
- Mitochondrial Substrate Availability and Its Role in Lipid-Induced Insulin Resistance and Proinflammatory Signaling in Skeletal MuscleLipina, Christopher, Macrae, Katherine, Suhm, Tamara, Weigert, Cora, Blachnio-Zabielska, Agnieszka, Baranowski, Marcin, Gorski, Jan, Burgess, Karl, Hundal, Harinder S. · 2013 · Diabetes · Retracted
- Adiponectin and its Hydrolase-Activated Receptors.Ankit X. Sharma, William L. Holland · 2017 · PubMed
- Chronic Treatment with Pioglitazone Does Not Protect Obese Patients with Diabetes Mellitus Type II from Free Fatty Acid-Induced Insulin ResistanceMireille J. M. Serlie, Gideon Allick, J.E.M. Groener, Mariëtte T. Ackermans, Rik Heijligenberg, Barbara C. Voermans, Johannes M. F. G. Aerts, Alfred J. Meijer, Hans P. Sauerwein · 2006 · The Journal of Clinical Endocrinology & Metabolism
- The role of perirenal adipose tissue deposition in chronic kidney disease progression: Mechanisms and therapeutic implicationsXiang Qiu, Xin Lan, Langhui Li, Huan Chen, NAIYU ZHANG, Xiaoli Zheng, Xiang Xie · 2024 · Life Sciences
- Stearic Acid Serves as a Potent Inhibitor of Protein Tyrosine Phosphatase 1BAyako Tsuchiya, Takeshi Kanno, Tomoyuki Nishizaki · 2013 · Cellular Physiology and Biochemistry
- Role of the atypical protein kinase Cζ in regulation of 5′-AMP-activated protein kinase in cardiac and skeletal muscleJohn R. Ussher, Jagdip S. Jaswal, Cory S. Wagg, Heather E Armstrong, David G. Lopaschuk, Wendy Keung, Gary D. Lopaschuk · 2009 · American Journal of Physiology-Endocrinology and Metabolism
- The effect of enterolactone on sphingolipid pathway and hepatic insulin resistance development in HepG2 cellsTomasz Charytoniuk, Nicoletta Iłowska, Klaudia Berk, Krzysztof Drygalski, Adrian Chabowski, Karolina Konstantynowicz-Nowicka · 2018 · Life Sciences
- Sphingolipids and Metabolic DiseaseL. Ashley Cowart · 2011 · Advances in experimental medicine and biology
- Circulating Sphingolipids and Glucose Homeostasis: An UpdateSarah Ali-Berrada, Jeanne Guitton, Sophie Tan, Anna G. Gyulkhandanyan, Éric Hajduch, Hervé Le Stunff · 2023 · International Journal of Molecular Sciences
- Differential regulation of stimulated glucose transport by free fatty acids and PPARα or -δ agonists in cardiac myocytesMohamed Asrih, Rene A. Lerch, Irène Papageorgiou, Corinne Pellieux, Christophe Montessuit · 2012 · American Journal of Physiology-Endocrinology and Metabolism
- Follicular Fluid Concentrations of Lipids and Their Metabolites Are Associated With Intraovarian Gonadotropin-Stimulated Androgen Production in Women Undergoing In Vitro FertilizationAlexandre Gervais, Marie‐Claude Battista, Belina Carranza‐Mamane, Hélène B. Lavoie, Jean‐Patrice Baillargeon · 2015 · The Journal of Clinical Endocrinology & Metabolism
- Muscle and liver-specific alterations in lipid and acylcarnitine metabolism after a single bout of exercise in miceMiriam Hoene, Jia Li, Yanjie Li, Heike Runge, Xinjie Zhao, Hans‐Ulrich Häring, Rainer Lehmann, Guowang Xu, Cora Weigert · 2016 · Scientific Reports
- Dietary bioactive compounds for type 2 diabetes: A comprehensive review of molecular interactions and mechanistic insightsOumayma Aguerd, Hamza Elhrech, Meryem El Fessikh, Khan Wen Goh, Nasreddine El Omari, Tarik Aanniz, Abdelhakim Bouyahya · 2025 · Journal of Functional Foods
- A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cellsIlaria Cimmino, Virginia Lorenzo, Francesca Fiory, Nunzianna Doti, Serena Ricci, Serena Cabaro, Antonietta Liotti, Luigi Vitagliano, Michele Longo, Claudia Miele et al. · 2017 · Oncotarget
- The expression of connexin 43 in children with Tetralogy of Fallot.Jacek Kołcz, Justyna Drukała, Małgorzata Bzowska, Bartłomiej Rajwa, W Korohoda, Edward J. Malec · 2005 · PubMed
- Muscle Cell Insulin Resistance Is Attenuated by Rosmarinic Acid: Elucidating the Mechanisms InvolvedDanja J. Den Hartogh, Filip Vlavcheski, Evangelia Tsiani · 2023 · International Journal of Molecular Sciences
- Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stressMahesh Kumar Verma, Aggunda Nagaraju Yateesh, Korrapati Neelima, Niketa Pawar, Kandoor Sandhya, Jayaram Poornima, Mudigere N Lakshmi, Sivakumaran Yogeshwari, Puttrevana M Pallavi, Anup Mammen Oommen et al. · 2014 · SpringerPlus
- NEU3 sialidase as a marker of insulin sensitivity: Regulation by fatty acidsChristopher Lipina, Francesca Nardi, Helen Grace, Harinder S. Hundal · 2015 · Cellular Signalling
- Sex-specific alterations in mRNA level of key lipid metabolism enzymes in skeletal muscle of overweight and obese subjects following endurance exerciseIra J. Smith, Kim M. Huffman, Michael T. Durheim, Brian D. Duscha, William E. Kraus · 2008 · Physiological Genomics
- Tous les acides gras saturés ont-ils le même effet métabolique ?Stéphane Walrand, François Fisch, J.M. Bourre · 2010 · Nutrition Clinique et Métabolisme
- eEF1A2 exacerbated insulin resistance in male skeletal muscle via PKCβ and ER stressMeng Guo, Yuna Li, Yan Wang, Zhenkun Li, Xiaohong Li, Peikun Zhao, Changlong Li, Jianyi Lv, Xin Liu, Xiaoyan Du et al. · 2019 · Journal of Endocrinology
- In Vitro Palmitate Treatment of Myotubes from Postmenopausal Women Leads to Ceramide Accumulation, Inflammation and Affected Insulin SignalingJulie Abildgaard, Darren C. Henstridge, Anette Tønnes Pedersen, Katherine G. Langley, Camilla Charlotte Scheele, Bente Klarlund Pedersen, Birgitte Lindegaard · 2014 · PLoS ONE
- AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: Role of nuclear respiratory factor-1Tasneem Adam, Lionel Henry Opie, M. Faadiel Essop · 2010 · Biochemical and Biophysical Research Communications
- Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2)Feng Wu Lin, Mohammed Akhter Hossain, Stephanie Post, Galina Karashchuk, Marc Tatar, Pierre DE MEYTS, John D. Wade · 2016 · Australian Journal of Chemistry