The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Signal transduction by vascular endothelial growth factor receptors
Open accessAbstract
VEGFs (vascular endothelial growth factors) control vascular development during embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There are five related mammalian ligands, which act through three receptor tyrosine kinases. Signalling is modulated through neuropilins, which act as VEGF co-receptors. Heparan sulfate and integrins are also important modulators of VEGF signalling. Therapeutic agents that interfere with VEGF signalling have been developed with the aim of decreasing angiogenesis in diseases that involve tissue growth and inflammation, such as cancer. The present review will outline the current understanding and consequent biology of VEGF receptor signalling.
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Cites
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Bergers, G., & Hanahan, D. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2442 · Cited by 2,953 · cited 1×
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BackgroundRole of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
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Mechanisms and regulation of endothelial VEGF receptor signalling
Simons, M., Gordon, E., & Claesson-Welsh, L. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.87 · Cited by 1,498
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The roles of vascular endothelial growth factor in bone repair and regeneration
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Metadata
- Authors
- Koch, S., Tugues, S., Li, X., Gualandi, L., & Claesson-Welsh, L.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 2011-06-28
- Volume
- 437
- Issue
- 2
- Pages
- 169-183
- ISSN
- 0264-6021 (ISSN-L)
- 1470-8728
- OpenAlex
- W2030537668
- Cited by
- 1,635
- References
- 8
- FWCI
- 36.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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