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Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin

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Holst, J J·1982·Biochemical Journal

Abstract

Enteroglucagon (II) was isolated from extracts of pig ileum mucosa by repeated gel filtrations, and its immunochemical and chromatographic characteristics were compared with those of a synthetic peptide corresponding to the 33-69 sequence of pig glicentin, before and after digestion with trypsin or trypsin followed by carboxypeptidase B, by using five region-specific assays covering most of the glicentin sequence. Enteroglucagon (II) and the synthetic peptide behave identically under three different conditions of chromatography as determined with all five assays (including a highly specific radioreceptor assay), and gave rise to similar fragments after enzyme digestion. It was therefore concluded that enteroglucagon (II) and the 33-69 sequence of glicentin are most probably identical.

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Metadata

Authors
Holst, J. J.
Venue
Biochemical Journal
Published
1982-12-01
Volume
207
Issue
3
Pages
381-388
ISSN
0264-6021 (ISSN-L)
OpenAlex
W2283885169
Cited by
176
References
0
FWCI
0.93
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin. https://app.cochat.ai/papers/10.1042/bj2070381
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Holst, J. J. (1982). Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin. Biochemical Journal. https://doi.org/10.1042/bj2070381

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.