Signalling through Class I PI3Ks in mammalian cells
Hawkins, P.T., Anderson, K.E., Davidson, K., Stephens, L.R.·2006·Biochemical Society Transactions
Cited by (556)
Items 101–200 of 556
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- Insulin-like Growth Factor-I Stimulates Shc-dependent Phosphatidylinositol 3-Kinase Activation via Grb2-associated p85 in Vascular Smooth Muscle CellsYashwanth Radhakrishnan, Laura A. Maile, Ling Yan, Lee M. Graves, David R. Clemmons · 2008 · Journal of Biological Chemistry
- p110δ PI3 kinase pathway: emerging roles in cancerNiki Tzenaki, Evangelia A. Papakonstanti · 2013 · Frontiers in Oncology
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- Class IA phosphatidylinositol 3-kinase: from their biologic implication in human cancers to drug discoverySauveur-Michel Maira, Charles F. Voliva, Carlos Garcı́a-Echeverrı́a · 2008 · Expert Opinion on Therapeutic Targets
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- Evidence against a Physiologic Role for Acute Changes in CNS Insulin Action in the Rapid Regulation of Hepatic Glucose ProductionChristopher Jerome Ramnanan, Dale S. Edgerton, Alan D. Cherrington · 2012 · Cell Metabolism
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- Dictyostelium uses ether‐linked inositol phospholipids for intracellular signallingJonathan P. Clark, Robert R. Kay, Anna Kielkowska, Izabella S. Niewczas, Louise Fets, David Oxley, Len Stephens, Phillip T. Hawkins · 2014 · The EMBO Journal
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- Activation of the PI3K/Akt signaling pathway through P2Y2 receptors by extracellular ATP is involved in osteoblastic cell proliferationSebastián Katz, Victoria Ayala, Graciela Edith Santillán, Ricardo Boland · 2011 · Archives of Biochemistry and Biophysics
- Structural Basis for Isoform Selectivity in a Class of Benzothiazole Inhibitors of Phosphoinositide 3-Kinase γPhilip N. Collier, Gabriel Martínez-Botella, Mark Cornebise, Kevin M. Cottrell, John Doran, James P. Griffith, Sudipta Mahajan, François Maltais, Cameron Stuver Moody, Emilie Porter Huck et al. · 2014 · Journal of Medicinal Chemistry
- Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology DomainEmmanuelle J. Meuillet · 2011 · Current Medicinal Chemistry
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- Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5-a]pyridinylpyridines in vitro and in vivoXiaomeng Wang, Jing Xu, Yiping Li, Huan Li, Congshan Jiang, Guangde Yang, Shemin Lu, San‐Qi Zhang · 2013 · European Journal of Medicinal Chemistry
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- PI3K Signaling Through the Dual GTPase–Activating Protein ARAP3 Is Essential for Developmental AngiogenesisLaure Gambardella, Myriam Hemberger, Bethany Hughes, Enrique Zudaire, Simon Andrews, Sonja Vermeren · 2010 · Science Signaling
- The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 ProteinWalliser, Claudia, Hermkes, Elisabeth, Schade, Anja, Wiese, Sebastian, Deinzer, Julia, Zapatka, Marc, Désiré, Laurent, Mertens, Daniel, Stilgenbauer, Stephan, Gierschik, Peter · 2016 · Journal of Biological Chemistry
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- Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS)Jon H. Come, Philip N. Collier, James A. Henderson, Albert C. Pierce, Robert J. Davies, Arnaud LeTiran, Hardwin O’Dowd, Upul K. Bandarage, Jingrong Cao, David D. Deininger et al. · 2018 · Journal of Medicinal Chemistry
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