Placental mTOR links maternal nutrient availability to fetal growth

Roos, Sara, Powell, Theresa L., Jansson, Thomas·2009·Biochemical Society Transactions

Cited by (156)

Items 101–156 of 156

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  2. The placental mTOR-pathway: correlation with early growth trajectories following intrauterine growth restriction?
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  3. Growth impairment, increased placental glucose uptake and altered transplacental transport in VIP deficient pregnancies: Maternal vs. placental contributions
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  6. IFPA Gabor Than Award lecture: Molecular control of placental growth: The emerging role of microRNAs
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  7. Regulation of hypoxia-inducible factor-1α, regulated in development and DNA damage response-1 and mammalian target of rapamycin in human placental BeWo cells under hypoxia
    Fengbiao Zhou, Liyang Guan, Pin Yu, X.D. Wang, Yayi Hu · 2016 · Placenta
  8. Suggested Mechanisms of Tracheal Occlusion Mediated Accelerated Fetal Lung Growth: A Case for Heterogeneous Topological Zones
    Ahmed I. Marwan, Uladzimir Shabeka, Evgenia Dobrinskikh · 2018 · Frontiers in Pediatrics
  9. Expression of growth-related genes in the mouse placenta is influenced by interactions between intestinal nematode (Heligmosomoides bakeri) infection and dietary protein deficiency
    Lisa M. Starr, Kristine G. Koski, Marilyn E. Scott · 2015 · International Journal for Parasitology
  10. The maternal circulation and placental shape
    Graham J. Burton, Eric R. M. Jauniaux · 2010 · Cambridge University Press eBooks
  11. Mechanisms linking energy balance and reproduction: impact of prenatal environment
    Erin Keen‐Rhinehart · 2016 · Hormone Molecular Biology and Clinical Investigation
  12. Altered lipid metabolism in rat offspring of dams fed a low-protein diet containing soy protein isolate
    Mi Young Yoon, Sae Bom Won, Young Hye Kwon · 2017 · Life Sciences
  13. The Placenta and Developmental Origins of Health and Disease
    Jane K. Cleal, Rohan M. Lewis · 2015 · Elsevier eBooks
  14. Syncytin-1 deficiency impairs placental nutrient transport via PI3K/Akt/mTOR signaling
    Xueling Chen, Xing-Xing Gong, Zhe-lei Xiong, Da Zhou, Ju Yang, Haifeng Zhang, Yun-shan Xue, Ya-nan Wang, Haibin Chen · 2025 · The Journal of Nutritional Biochemistry
  15. Placental mTOR signalling links mitochondrial dysfunction, nutrient transport and neonatal beta cell perturbations in mice
    Megan Beetch, Eunice I. Oribamise, Seokwon Jo, Briana Clifton, Sarah N. Larson, Alex Hausmann, Alicia Wong, Brian Akhaphong, Elizabeth Morgan, Emilyn U. Alejandro · 2025 · Diabetologia
  16. mTOR is an essential gate in adapting the functional response of ovine trophoblast cells under stress-inducing environments
    Irene Viola, Paolo Accornero, Isabella Manenti, Silvia Miretti, Mario Baratta, Paola Toschi · 2024 · Placenta
  17. Maternal inflammation leads to different mTORC1 activity varied by anatomic locations in mouse placenta†
    Jie Dong, Na E. Shin, Ji Yeon Lee, Bei Jia, Anna Chudnovets, Michael W. McLane, Li Su, Quan Na, Jun Lei, Irina D. Burd · 2019 · Biology of Reproduction
  18. Impact of placental mTOR deficiency on peripheral insulin signaling in adult mice offspring
    Megan Beetch, Brian Akhaphong, Alicia Wong, Briana Clifton, Seokwon Jo, Ramkumar Mohan, Juan E. Abrahante, Emilyn U. Alejandro · 2023 · Journal of Molecular Endocrinology
  19. Oleic acid stimulation of amino acid uptake in primary human trophoblast cells is mediated by phosphatidic acid and mTOR signaling
    Elena Silva, Véronique Ferchaud‐Roucher, Anita W. Kramer, Lana Madi, Priyadarshini Pantham, Stephanie S. Chassen, Thomas Jansson, Theresa L. Powell · 2023 · FASEB BioAdvances
  20. Valproic acid inhibits cell size and cell proliferation by AMPK-mediated mTOR signaling pathway in JEG-3 cells
    Youn‐Jung Kim, Jina Lee, Mi‐Kyung Song, Taejun Han, Jae‐Chun Ryu · 2013 · BioChip Journal
  21. Modulatory role of mTOR in trophoblast adaptive response in the early stage of placentation in sheep
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  22. Fetal growth and congenital heart disease at high altitude
    Dino A. Giussani · 2025 · Philosophical Transactions of the Royal Society B Biological Sciences
  23. CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns
    Emma Barroso, Marta Díaz, Ana Cristina Reguera, Mona Peyman, Jesús Balsinde, Javier Jurado-Aguilar, Meijian Zhang, Adel Rostami, Xavier Palomer, Lourdes Ibáñez et al. · 2023 · Cell Communication and Signaling
  24. Targeted Multiplex Gene Expression Profiling to Measure High-Fat Diet and Metformin Effects on Fetal Gene Expression in a Mouse Model
    Neeta L. Vora, Matthew R. Grace, Lisa Smeester, Sarah Kathleen Dotters-Katz, Rebecca C. Fry, Victoria Lin Bae-Jump, Kim Boggess · 2018 · Reproductive Sciences
  25. Hypoxia-induced regulation of placental REDD1 and mTOR was impaired in a rat model of estrogen-induced cholestasis
    Fan Zhou, Huafang Chen, Xiaodong Wang, Pin Yu, Yayi Hu · 2016 · Archives of Gynecology and Obstetrics
  26. Gene and Protein Expression of Placental Nutrient-Stress Sensor Proteins in Fetal Growth Restriction
    Elizabeth Morgan, Grace Chung, Seokwon Jo, Briana Clifton, Sarah A. Wernimont, Emilyn U. Alejandro · 2024 · Stresses
  27. The placental role in developmental programming
    Rohan M. Lewis, Jane K. Cleal, Keith M. Godfrey · 2022 · Elsevier eBooks
  28. Basic Experimental and Clinical Advances in the Mechanisms Underlying Abnormal Pregnancy Outcomes
    Timothy R.H. Regnault, Mark J. Nijland, Helen Budge, Janna Leigh Morrison · 2013 · Journal of Pregnancy
  29. Metabolic imprinting in trophoblast barrier dysfunction: the role of glucolipotoxicity, endoplasmic reticulum stress, and amino acid transport imbalance
    Shuo Zhang, Zi Xuan Shen, Pin Cao, Sha Ni, Dan Wang · 2026 · Journal of Assisted Reproduction and Genetics
  30. Upregulation of miR-181a-5p and miR-125b-2-3p in the Maternal Circulation of Fetuses with Rh-Negative Hemolytic Disease of the Fetus and Newborn Could Be Related to Dysfunction of Placental Function
    Xiaohui Xie, Mei Jiang, Zhengai Xiong, Xiao-Qin Huang · 2022 · Disease Markers
  31. Assisted reproductive technology causes reduced expression of amino acid transporters in human full-term placentas
    Qingge Jia, Xiangyu Guo, Qi Ping Cao, Man Di, Fei Yao, Hui Lei, Yameng Sun, Tianqi Xu, Jingjing Wang, Mingyang Li et al. · 2022 · Pathology - Research and Practice
  32. Placental, Foetal, and Maternal Serum Metabolomic Profiles in Pregnancy-Associated Cancer: Walker-256 Tumour Model in a Time-Course Analysis
    Carla de Moraes Salgado, Laís Rosa Viana, Maria Cristina Cintra Gomes‐Marcondes · 2023 · International Journal of Molecular Sciences
  33. The placental roots of cardiovascular disease
    Kent L. R. Thornburg, Perrie Faye O'Tierney, Terry K. Morgan, Samantha Louey · 2010 · Cambridge University Press eBooks
  34. Assessment of Placental Sodium-Independent Leucine Uptake and Transfer in Trophoblast Cells
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  35. Longitudinal Magnetic Resonance Imaging Study of Hemodynamic Changes in the Third Trimester in Fetuses With Major Congenital Heart Defects and Healthy Fetuses
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  36. IGF-1Eb Isoform Immunoreactivity May Be Associated with Placental Dysfunction and Vascular Pathology in Fetal Growth Restriction (FGR)
    Apostolos Fasoulopoulos, Michail N. Varras, Fani‐Niki Varra, Viktoria‐Konstantina Varra, Αnastassios Philippou, Alexandros Gryparis, Αrgyro Papadopetraki, Petros Stellatos, Athina Pesiridou, Kleopatra Paparizou et al. · 2026 · Biomolecules
  37. Leucine and Fetal Growth
    Júlio Tirapegui, Daiana Vianna, Gabriela Fullin Resende Teodoro, Lucas C. Pantaleão · 2014 · Springer eBooks
  38. Effects of glucose and fatty acids interactions on glucose metabolism pathways in human trophoblasts
    Carina Bertoldi Franco · 2015 · ANU Open Research (Australian National University)
  39. Expression of Downstream Targets of mTOR in Response to a Model of Maternal Undernutrition and Hypoxia
    Jessica L. Groth · 2012 · eCommons (Cornell University)
  40. The placental role in fetal programming
    Rohan M. Lewis, Jane K. Cleal, Keith M. Godfrey · 2011 · Elsevier eBooks
  41. mTOR Signalling, Nutrients and Disease
    Deborah C. I. Goberdhan, Robert S. Boyd, Richard F. Lamb · 2008
  42. The Placental Role in Developmental Programming
    Rohan M. Lewis, Jane K. Cleal, Keith M. Godfrey · 2017 · Elsevier eBooks
  43. The Evolution of Live Birth and the Insulin and Insulin-like Signaling Network in Sceloporus Lizards
    Aundrea K. Westfall · 2018
  44. N-carbamoylglutamate supplementation in late-gestation dairy cows is associated with increased newborn weight and improved nutrient supply in the placentome
    Fengfei Gu, Luyi Jiang, Linyu Xie, Diming Wang, Jianxin Liu · 2020
  45. Adaptações placentárias e desfecho fetal em prole de mães com obesidade induzida por dieta hiperlipídica
    Ana Paula Varela Sanches · 2020
  46. Placental Insulin-Like Growth Factor-1 Receptor, Protein Kinase B and Mammalian Target of Rapamycin are Downregulated in HIV-1 Positive Women on Antiretroviral Drugs
    Winifrida Benedict Kidima, Gatambwa Mukandala, Osiana Leonard, Daniel Nkungu · 2021 · Tanzania Journal of Science
  47. Intrauterine Aspects
    Siegfried Zabransky · 2013
  48. Avaliação dos efeitos da suplementação nutricional com leucina sobre a atividade placentárias de ratas portadoras de tumor de Walker 256 ao longo da prenhez
    Carla de Moraes Salgado · 2021
  49. Additional file 1 of Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition
    Sedlmeier, Eva-Maria, Dorothy Marie Meyer, Lynne Stecher, Manuela Sailer, Daniel, Hannelore, Hauner, Hans, B. Bader · 2021 · Figshare
  50. Additional file 1 of CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns
    Emma Barroso, Marta Díaz, Reguera, Ana Cristina, Mona Peyman, Jesús Balsinde, Javier Jurado-Aguilar, Meijian Zhang, Adel Rostami, Xavier Palomer, Lourdes Ibáñez et al. · 2024 · Figshare
  51. Additional file 2 of Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition
    Sedlmeier, Eva-Maria, Dorothy Marie Meyer, Lynne Stecher, Manuela Sailer, Daniel, Hannelore, Hauner, Hans, B. Bader · 2021 · Figshare
  52. Additional file 5 of Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition
    Sedlmeier, Eva-Maria, Dorothy Marie Meyer, Lynne Stecher, Manuela Sailer, Daniel, Hannelore, Hauner, Hans, B. Bader · 2021 · Figshare
  53. Additional file 4 of Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition
    Sedlmeier, Eva-Maria, Dorothy Marie Meyer, Lynne Stecher, Manuela Sailer, Daniel, Hannelore, Hauner, Hans, B. Bader · 2021 · Figshare
  54. Additional file 3 of Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition
    Sedlmeier, Eva-Maria, Dorothy Marie Meyer, Lynne Stecher, Manuela Sailer, Daniel, Hannelore, Hauner, Hans, B. Bader · 2021 · Figshare
  55. Intergenerational effects of early life programming: The role of glucocorticoids and maternal obesity
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  56. Convergence of MTOR and Glucocorticoid receptor signalling in the human placenta: effects of pre-term labour, nutrition and maternal stress
    D. Mparmpakas · 2011 · Brunel University Research Archive (BURA) (Brunel University London)