The ATP synthase: the understood, the uncertain and the unknown

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Direct observation of the rotation of F1-ATPase

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The Whole Structure of the 13-Subunit Oxidized Cytochrome c Oxidase at 2.8 Å

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RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION

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Molecular Architecture of the Rotary Motor in ATP Synthase

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Complete Structure of the 11-Subunit Bovine Mitochondrial Cytochrome bc 1 Complex

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The binding change mechanism for ATP synthase--some probabilities and possibilities.

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Architecture of succinate dehydrogenase and reactive oxygen species generation

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Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II

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Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase

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A Naturally Occurring Inhibitor of Mitochondrial Adenosine Triphosphatase

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Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

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The architecture of respiratory complex I

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Chemiosmotic coupling in oxidative and photosynthetic phosphorylation

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Macromolecular organization of ATP synthase and complex I in whole mitochondria

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Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria

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The structure of the central stalk in bovine F(1)-ATPase at 2.4 A resolution.

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Structure of Bovine Mitochondrial F1-ATPase with Nucleotide Bound to All Three Catalytic Sites

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The molecular mechanism of ATP synthesis by F1F0-ATP synthase

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Primary structure and subunit stoichiometry of F1-ATPase from bovine mitochondria.

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Mechanism of inhibition of bovine F 1 -ATPase by resveratrol and related polyphenols

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Structure of the Rotor Ring of F-Type Na + -ATPase from Ilyobacter tartaricus

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Structure of the membrane domain of respiratory complex I

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P/O ratios of mitochondrial oxidative phosphorylation

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THE HISTORY OF CELL RESPIRATION AND CYTOCHROME

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A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection

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The History of Cell Respiration and Cytochrome

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Reversible redox energy coupling in electron transfer chains

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Role of a disulfide bond in the gamma subunit in activation of the ATPase of chloroplast coupling factor 1.

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How azide inhibits ATP hydrolysis by the F-ATPases

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Phospholipid composition of highly purified mitochondrial outer membranes of rat liver and Neurospora crassa. Is cardiolipin present in the mitochondrial outer membrane?

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Tightly associated cardiolipin in the bovine heart mitochondrial ATP synthase as analyzed by 31P nuclear magnetic resonance spectroscopy.

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Structure of the ATP synthase catalytic complex (F1) from Escherichia coli in an autoinhibited conformation

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Primary sodium ion translocating enzymes

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Structure of the mitochondrial ATP synthase by electron cryomicroscopy

Rubinstein, J. L., Walker, J. E., & Henderson, R. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg608 · Cited by 216

Asymmetric distribution of phospholipids in the inner membrane of beef heart mitochondria.

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The rotary mechanism of the ATP synthase

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The structure of bovine F1-ATPase in complex with its regulatory protein IF1

Cabezón, E., Montgomery, M. G., Leslie, A. G. W., & Walker, J. E. (2003) · Nature Structural & Molecular Biology · doi:10.1038/nsb966 · Cited by 213

How the regulatory protein, IF 1 , inhibits F 1 -ATPase from bovine mitochondria

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A model for conformational coupling of membrane potential and proton translocation to ATP synthesis and to active transport

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Structure of dimeric ATP synthase from mitochondria: An angular association of monomers induces the strong curvature of the inner membrane

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Identification of the subunits of F1F0-ATPase from bovine heart mitochondria

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Modulation of the Oligomerization State of the Bovine F1-ATPase Inhibitor Protein, IF1, by pH

Cabezón, E., Butler, P. J. G., Runswick, M. J., & Walker, J. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003859200 · Cited by 192

The peripheral stalk of the mitochondrial ATP synthase

Walker, J. E., & Dickson, V. K. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2006.01.001 · Cited by 190

Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 Aå Resolution

Bowler, M. W., Montgomery, M. G., Leslie, A. G. W., & Walker, J. E. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700203200 · Cited by 188

On the structure of the stator of the mitochondrial ATP synthase

Dickson, V. K., Silvester, J. A., Fearnley, I. M., Leslie, A. G. W., & Walker, J. E. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601177 · Cited by 187

High-resolution structure of the rotor ring of a proton-dependent ATP synthase

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The structure of the membrane extrinsic region of bovine ATP synthase

Rees, D. M., Leslie, A. G. W., & Walker, J. E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910365106 · Cited by 180

Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase

Kabaleeswaran, V., Puri, N., Walker, J. E., Leslie, A. G. W., & Mueller, D. M. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601410 · Cited by 179

The structure of bovine F1-ATPase complexed with the antibiotic inhibitor aurovertin B.

van Raaij, M. J., Abrahams, J. P., Leslie, A. G. W., & Walker, J. E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.14.6913 · Cited by 175

F0 Membrane Domain of ATP Synthase from Bovine Heart Mitochondria: Purification, Subunit Composition, and Reconstitution with F1-ATPase

Collinson, I. R., Runswick, M. J., Buchanan, S. K., Fearnley, I. M., Skehel, M. J., van Raaij, M. J., Griffiths, D. E., & Walker, J. E. (1994) · Biochemistry · doi:10.1021/bi00191a026 · Cited by 167

The structure of bovine F1‐ATPase inhibited by ADP and beryllium fluoride

Kagawa, R., Montgomery, M. G., Braig, K., Leslie, A. G. W., & Walker, J. E. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600293 · Cited by 161

Structure of bovine mitochondrial F1-ATPase inhibited by Mg2+ADP and aluminium fluoride

Braig, K., Menz, R. I., Montgomery, M. G., Leslie, A. G., & Walker, J. E. (2000) · Structure · doi:10.1016/s0969-2126(00)00145-3 · Cited by 161

Proton Translocation by the F1FOATPase of Escherichia coli

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Two overlapping genes in bovine mitochondrial DNA encode membrane components of ATP synthase.

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The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin.

Abrahams, J. P., Buchanan, S. K., van Raaij, M. J., Fearnley, I. M., Leslie, A. G. W., & Walker, J. E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9420 · Cited by 154

Transient accumulation of elastic energy in proton translocating ATP synthase

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Structure of the gamma-epsilon complex of ATP synthase.

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A Dynamic Analysis of the Rotation Mechanism for Conformational Change in F1-ATPase

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The structure of bovine IF1, the regulatory subunit of mitochondrial F‐ATPase

Cabezón, E., Runswick, M. J., Leslie, A. G. W., & Walker, J. E. (2001) · The EMBO Journal · doi:10.1093/emboj/20.24.6990 · Cited by 146

Rotation of the c subunit oligomer in fully functional F 1 F o ATP synthase

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ATP synthase from bovine mitochondria

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Structure of the Membrane Domain of Subunit b of theEscherichia coli F0F1 ATP Synthase

Dmitriev, O. Y., Jones, P. C., Jiang, W., & Fillingame, R. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.22.15598 · Cited by 135

Transmembrane Topography of Subunit a in theEscherichia coli F1F0 ATP Synthase

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The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic−Aromatic Interaction in Inhibition,

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Structural organization of mitochondrial ATP synthase

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Cooperative three-step motions in catalytic subunits of F1-ATPase correlate with 80° and 40° substep rotations

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Structure of the c14 Rotor Ring of the Proton Translocating Chloroplast ATP Synthase

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Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM

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ATP Synthase from Bovine Heart Mitochondria

Collinson, I. R., van Raaij, M. J., Runswick, M. J., Fearnley, I. M., Skehel, M. J., Orriss, G. L., Miroux, B., & Walker, J. E. (1994) · Journal of Molecular Biology · doi:10.1006/jmbi.1994.1591 · Cited by 114

Subnanometre-resolution structure of the intact Thermus thermophilus H+-driven ATP synthase

Lau, W. C. Y., & Rubinstein, J. L. (2011) · Nature · doi:10.1038/nature10699 · Cited by 113

Electron tomography of plant thylakoid membranes

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Domain compliance and elastic power transmission in rotary F O F 1 -ATPase

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Dimerization of Bovine F1-ATPase by Binding the Inhibitor Protein, IF1

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Solution structure of the N-terminal domain of the δ subunit of the E. coli ATPsynthase

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The regulation of catalysis in ATP synthase

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ATP synthase in slow- and fast-growing mycobacteria is active in ATP synthesis and blocked in ATP hydrolysis direction

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Solution Structure of the ε Subunit of the F1-ATPase from Escherichia coli and Interactions of This Subunit with β Subunits in the Complex

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Bovine F1-ATPase covalently inhibited with 4-chloro-7-nitrobenzofurazan: the structure provides further support for a rotary catalytic mechanism

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ATP synthase and other motor proteins

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Macromolecules that prefer their membranes curvy

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Row-like organization of ATP synthase in intact mitochondria determined by cryo-electron tomography

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Subunit equivalence in Escherichia coli and bovine heart mitochondrial F1F0 ATPases

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Crystal Structure of the Mg·ADP-inhibited State of the Yeast F1c10-ATP Synthase

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Inhibitory properties of endogenous subunit ϵ in the Escherichia coli F1 ATPase

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Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F 1 –ATPase from bovine heart mitochondria

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ε Subunit, an Endogenous Inhibitor of Bacterial F1-ATPase, Also Inhibits F0F1-ATPase

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Aqueous access pathways in subunit a of rotary ATP synthase extend to both sides of the membrane

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Localization of the δ subunit in the Escherichia coli F 1 F 0 -ATPsynthase by immuno electron microscopy: the δ subunit binds on top of the F 1 1 1Edited by W. Baumeister

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The c13 Ring from a Thermoalkaliphilic ATP Synthase Reveals an Extended Diameter Due to a Special Structural Region

Matthies, D., Preiß, L., Klyszejko, A. L., Müller, D. J., Cook, G. M., Vonck, J., & Meier, T. W. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.03.052 · Cited by 72

Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms 1 1Edited by W. Baumeister

Sazanov, L. A., & Walker, J. E. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.4079 · Cited by 71

Lysine 43 Is Trimethylated in Subunit c from Bovine Mitochondrial ATP Synthase and in Storage Bodies Associated with Batten Disease

Chen, R., Fearnley, I. M., Palmer, D. N., & Walker, J. E. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402074200 · Cited by 65

Cryo-EM Structure of the Yeast ATP Synthase

Lau, W. C. Y., Baker, L. A., & Rubinstein, J. L. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.08.014 · Cited by 64

Binding of the Inhibitor Protein IF1 to Bovine F1-ATPase

Bason, J. V., Runswick, M. J., Fearnley, I. M., & Walker, J. E. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.12.025 · Cited by 64

Purification and Biochemical Characterization of the F 1 F o -ATP Synthase from Thermoalkaliphilic Bacillus sp. Strain TA2.A1

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Structure of the F1-binding Domain of the Stator of Bovine F1Fo-ATPase and How it Binds an α-Subunit

Carbajo, R. J., Kellas, F. A., Runswick, M. J., Montgomery, M. G., Walker, J. E., & Neuhaus, D. (2005) · Journal of Molecular Biology · doi:10.1016/j.jmb.2005.06.012 · Cited by 63

Functional Halt Positions of Rotary FOF1-ATPase Correlated with Crystal Structures

Sielaff, H., Rennekamp, H., Engelbrecht, S., & Junge, W. (2008) · Biophysical Journal · doi:10.1529/biophysj.108.139782 · Cited by 62

ATP Synthase b Subunit Dimerization Domain: A Right-Handed Coiled Coil with Offset Helices

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A novel 11‐kDa inhibitory subunit in the F 1 F O ATP synthase of Paracoccus denitrificans and related α‐proteobacteria

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Aqueous Access Pathways in ATP Synthase Subunit a

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Asymmetric Structure of the Yeast F1 ATPase in the Absence of Bound Nucleotides

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Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria

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Nobel Lectures in Chemistry 1981 – 1990

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Structure, Mechanism and Regulation of ATP Synthases

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F-ATPases

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