Cardiovascular Structural Adaptation; its Role in the Initiation and Maintenance of Primary Hypertension

Folkow, Björn

doi:10.1042/cs055003s

Cited by 404Blood Pressure and Hypertension StudiesCardiovascular Health and Disease PreventionRenin-Angiotensin System Studies

Cardiovascular Structural Adaptation; its Role in the Initiation and Maintenance of Primary Hypertension

Folkow, Björn·1978·Clinical Science

DOI 10.1042/cs055003s

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Abstract

Conference Abstract| December 01 1978 Cardiovascular Structural Adaptation; its Role in the Initiation and Maintenance of Primary Hypertension Björn Folkow Björn Folkow 1Department of Physiology, University of Göteborg, Sweden Search for other works by this author on: This Site PubMed Google Scholar Clin Sci Mol Med (1978) 55 (s4): 3s–22s. https://doi.org/10.1042/cs055003s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation Björn Folkow; Cardiovascular Structural Adaptation; its Role in the Initiation and Maintenance of Primary Hypertension. Clin Sci Mol Med 1 December 1978; 55 (s4): 3s–22s. doi: https://doi.org/10.1042/cs055003s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1978 The Biochemical Society and the Medical Research Society1978 Article PDF first page preview Close Modal You do not currently have access to this content.

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Arteriolar remodeling in hypertension, which makes the elevation of total peripheral resistance partly dependent on structural factors, is in large part mediated by sympathetic neural influences through direct effects on components of the arterial vascular wall.
“Finally, the arteriolar remodeling that characterizes hypertension and makes the elevation of total peripheral resistance partly dependent on structural factors, ie, an increased wall-to-lumen ratio, has been found to be in large part mediated by sympathetic neural influences throughout direct effects on the different components of the arterial vascular wall52,53.”
From The Sympathetic Nervous System Alterations in Human Hypertension (2015) · cites this paper as [52]

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“As highlighted elsewhere, the seminal studies of Folkow infer that changes in arterial wall thickness can exacerbate effects on arterial pressure in vivo (74, 75).”
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Self-citation

Authors: Folkow, B.
Affiliations: University of Gothenburg (SE)
Corresponding author: Folkow, Björn
Venue: Clinical Science
Publisher: Portland Press Ltd.
Published: 1978-01-01
Volume: 55
Issue: s4
Pages: 3s-22s
ISSN: 0144-4107 (ISSN-L)
DOI: 10.1042/cs055003s
OpenAlex: W2400501115
Cited by: 403
References: 0
Citations by year: 2024: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 1 · 2017: 2 · 2016: 1 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 5
FWCI: 13.54
Type: journal article
Language: en
Open access: closed
Locations: Clinical Science (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Renin-Angiotensin System Studies
Keywords: essential hypertension, hypertension maintenance, vascular remodeling, cardiac hypertrophy
MeSH terms: Animals, Coronary Circulation, Coronary Vessels, Disease Models, Animal, Cardiomegaly, Humans, Hypertension, Hypertension, Renovascular, Muscle, Smooth, Pressoreceptors, Vascular Resistance, Vasomotor System, Rats

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Cardiovascular Structural Adaptation; its Role in the Initiation and Maintenance of Primary Hypertension

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