The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Understanding biochemistry: structure and function of nucleic acids
Open accessAbstract
Nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), carry genetic information which is read in cells to make the RNA and proteins by which living things function. The well-known structure of the DNA double helix allows this information to be copied and passed on to the next generation. In this article we summarise the structure and function of nucleic acids. The article includes a historical perspective and summarises some of the early work which led to our understanding of this important molecule and how it functions; many of these pioneering scientists were awarded Nobel Prizes for their work. We explain the structure of the DNA molecule, how it is packaged into chromosomes and how it is replicated prior to cell division. We look at how the concept of the gene has developed since the term was first coined and how DNA is copied into RNA (transcription) and translated into protein (translation).
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Cites
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171737a0 · Cited by 13,584
General Nature of the Genetic Code for Proteins
CRICK, F. H. C., BARNETT, L., BRENNER, S., & WATTS-TOBIN, R. J. (1961) · Nature · doi:10.1038/1921227a0 · Cited by 1,390
Molecular Configuration in Sodium Thymonucleate
FRANKLIN, R. E., & GOSLING, R. G. (1953) · Nature · doi:10.1038/171740a0 · Cited by 1,330
The replication of DNA in Escherichia coli
Meselson, M., & Stahl, F. W. (1958) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.44.7.671 · Cited by 1,262
What is a gene, post-ENCODE? History and updated definition
Gerstein, M. B., Bruce, C., Rozowsky, J. S., Zheng, D., Du, J., Korbel, J. O., Emanuelsson, O., Zhang, Z. D., Weissman, S., & Snyder, M. (2007) · Genome Research · doi:10.1101/gr.6339607 · Cited by 699
Discovering DNA: Friedrich Miescher and the early years of nucleic acid research
Dahm, R. (2008) · Human Genetics · doi:10.1007/s00439-007-0433-0 · Cited by 388
Telomeres and Telomerase: The Means to the End (Nobel Lecture)
Blackburn, E. H. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201002387 · Cited by 226
The double helix and the 'wronged heroine'
Maddox, B. (2003) · Nature · doi:10.1038/nature01399 · Cited by 92
The eukaryotic transcriptional machinery: complexities and mechanisms unforeseen
Roeder, R. (2003) · Nature Medicine · doi:10.1038/nm938 · Cited by 66
The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes
Myasnikov, A. G., Afonina, Z. A., Ménétret, J., Shirokov, V. A., Spirin, A. S., & Klaholz, B. P. (2014) · Nature Communications · doi:10.1038/ncomms6294 · Cited by 53
Cited by
Muolokwu, C. E., Chaulagain, B., Gothwal, A., Mahanta, A. K., Tagoe, B., Lamsal, B., & Singh, J. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1405423 · Cited by 42
Systematic benchmarking of deep-learning methods for tertiary RNA structure prediction
Bahai, A., Kwoh, C. K., Mu, Y., & Li, Y. (2024) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1012715 · Cited by 12
Abdalla, O., Walker, C., & Ishimori, K. (2024) · Software Impacts · doi:10.1016/j.simpa.2024.100661 · Cited by 6
Metadata
- Authors
- Minchin, S., & Lodge, J.
- Venue
- Essays in Biochemistry
- Publisher
- Portland Press Ltd.
- Published
- 2019-10
- Volume
- 63
- Issue
- 4
- Pages
- 433-456
- ISSN
- 0071-1365 (ISSN-L)
- 1744-1358
- OpenAlex
- W2982034981
- Cited by
- 264
- References
- 15
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
