Jasmonates: Biosynthesis, perception and signal transduction
Open accessAbstract
Jasmonates (JAs) are physiologically important molecules involved in a wide range of plant responses from growth, flowering, senescence to defence against abiotic and biotic stress. They are rapidly synthesised from α-linolenic acid (ALA; C18:3 ∆9,12,15) by a process of oxidation, cyclisation and acyl chain shortening involving co-operation between the chloroplast and peroxisome. The active form of JA is the isoleucine conjugate, JA-isoleucine (JA-Ile), which is synthesised in the cytoplasm. Other active metabolites of JA include the airborne signalling molecules, methyl JA (Me-JA) and cis-jasmone (CJ), which act as inter-plant signalling molecules activating defensive genes encoding proteins and secondary compounds such as anthocyanins and alkaloids. One of the key defensive metabolites in many plants is a protease inhibitor that inactivates the protein digestive capabilities of insects, thereby, reducing their growth. The receptor for JA-Ile is a ubiquitin ligase termed as SCFCoi1 that targets the repressor protein JA Zim domain (JAZ) for degradation in the 26S proteasome. Removal of JAZ allows other transcription factors (TFs) to activate the JA response. The levels of JA-Ile are controlled through catabolism by hydroxylating enzymes of the cytochrome P450 (CYP) family. The JAZ proteins act as metabolic hubs and play key roles in cross-talk with other phytohormone signalling pathways in co-ordinating genome-wide responses. Specific subsets of JAZ proteins are involved in regulating different response outcomes such as growth inhibition versus biotic stress responses. Understanding the molecular circuits that control plant responses to pests and pathogens is a necessary pre-requisite to engineering plants with enhanced resilience to biotic challenges for improved agricultural yields.
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Info-chemicals such as methyl jasmonate have been identified in terrestrial plants and signal herbivorous attack between plants.
“Info-chemicals have been identified in terrestrial plants such as methyl jasmonate that signal herbivorous attack between plants [51].”
From Key Targets for Improving Algal Biofuel Production (2021) · cites this paper as [51]
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Key Targets for Improving Algal Biofuel Production
Griffiths, G., Hossain, A. K., Sharma, V., & Duraisamy, G. (2021) · Clean Technologies · doi:10.3390/cleantechnol3040043 · Cited by 49 · see citing works
Self-citation
- Authors
- Griffiths, G.
- Affiliations
- Aston University (GB)
- Corresponding author
- Griffiths, Gareth
- ORCID
- Griffiths, Gareth
- Venue
- Essays in Biochemistry
- Publisher
- Portland Press Ltd.
- Published
- 2020-06-30
- Volume
- 64
- Issue
- 3
- Pages
- 501-512
- ISSN
- 0071-1365 (ISSN-L)
- 1744-1358
- OpenAlex
- W3039177061
- Cited by
- 103
- References
- 53
- Citations by year
- 2026: 22 · 2025: 15 · 2024: 22 · 2023: 17 · 2022: 18 · 2021: 9
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Essays in Biochemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Aston Publications Explorer (Aston University) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect-Plant Interactions and Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant-Microbe Interactions and Immunity
- Keywords
- jasmonates, jasmonate biosynthesis, signal transduction, jasmonoyl-isoleucine, methyl jasmonate, cis-jasmone, plant defense, JAZ proteins, proteasomal degradation, phytohormone crosstalk, plant-pest interactions, plant-pathogen interaction, plant growth regulation
- MeSH terms
- Acetates, Chloroplasts, Cyclopentanes, Isoleucine, Plant Growth Regulators, Plants, Transcription Factors, Signal Transduction, Gene Expression Regulation, Plant, Ubiquitin-Protein Ligases, Oxylipins
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