Recurrences in Sudden Sensorineural Hearing Loss: A Long-Term Observational Study
Abstract
Purpose Long-term outcomes of sudden sensorineural hearing loss (SSNHL) are poorly studied. The recurrence rate is heterogeneous, and the prognosis of relapses is uncertain. The aim of this retrospective study was to evaluate the recurrence rate of SSNHL and to analyze the correlation with clinical and audiometric characteristics. Method Seventy-three patients with idiopatic SSNHL were evaluated. Clinical and audiometric features were recorded. Seventy patients (95.8%) had at least a 2-year follow-up, whereas 50 (68.4%) had a 5-year follow-up. Results Two- and 5-year recurrence rates were 5.60% and 10.34%, respectively. Mean time lapse between 1st episode and recurrence was 29.33 ± 26.60 months. About 70% of patients had a partial recovery at recurrence. The same ear was affected in 42.8% of patients, the contralateral ear was affected in 42.8% of patients, and recurrence was bilateral in 14.4% of cases. Recurrence correlated only with the presence of tinnitus during follow-up. However, the small number of participants with recurrence represented a limiting factor of our study. Conclusions Recurrences of SSNHL are rare events that can involve ipsilateral or contralateral ear. Further studies are necessary to identify predictors of recurrence.
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The cumulative relapse rates in studies included in the systematic review ranged from 4.9% to 47%.
“The cumulative relapse rates in studies included in the systematic review ranged from 4.9% to 47% [7,8,16].”
From Prognostic Factors Associated with Recovery from Recurrent Idiopathic Sudden Sensorineural Hearing Loss: Retrospective Analysis and Systematic Review (2022) · cites this paper as [16]
Cites
Hearing outcome of recurrent sudden deafness: Ipsilateral versus contralateral types
Kuo, Y.-L., & Young, Y.-H. (2012) · Acta Oto-Laryngologica · doi:10.3109/00016489.2011.642817 · Cited by 17 · see citing works
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Jeon, S. Y., Kang, D. W., Kim, S. H., Byun, J. Y., & Yeo, S. G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051453 · Cited by 9 · see citing works
Recurrent sudden sensorineural hearing loss—A literature review
Zhang, B., Wang, Y., & Chan, K. (2022) · Laryngoscope Investigative Otolaryngology · doi:10.1002/lio2.828 · Cited by 9 · see citing works
- Authors
- Pecorari, G., Riva, G., Bruno, G., Naqe, N., Nardo, M., Albera, A., & Albera, R.
- Affiliations
- University of Turin (IT)
- Venue
- American Journal of Audiology
- Published
- 2020-03-05
- Volume
- 29
- Issue
- 1
- Pages
- 18-22
- ISSN
- 1059-0889 (ISSN-L)
- 1558-9137
- OpenAlex
- W2999038897
- Cited by
- 11
- References
- 1
- Citations by year
- 2026: 3 · 2025: 1 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 2
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Audiology (publishedVersion)
- PubMed (publishedVersion)
- PORTO@Iris (submittedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- sudden sensorineural hearing loss, recurrence, relapse, idiopathic hearing loss, tinnitus, long-term outcomes, bilateral hearing loss, ipsilateral recurrence, predictors of recurrence
- MeSH terms
- Injection, Intratympanic, Administration, Oral, Adolescent, Adult, Aged, Aged, 80 and over, Audiometry, Pure-Tone, Betamethasone, Child, Hearing Loss, Sudden, Diuretics, Osmotic, Female, Glucocorticoids, Hearing Loss, Sensorineural, Humans, Hyperbaric Oxygenation, Longitudinal Studies, Male, Mannitol, Middle Aged, Recurrence, Time Factors, Retreatment, Recovery of Function, Young Adult, Administration, Intravenous
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