The DOI matches its Crossref record.
Marijuana withdrawal among adults seeking treatment for marijuana dependence.
Abstract
AIMS: The clinical relevance of marijuana withdrawal has not been established. This study is the first to document the incidence and severity of perceived marijuana withdrawal symptoms in a clinical sample of marijuana-dependent adults. MEASUREMENTS: Fifty-four people seeking outpatient treatment for marijuana dependence completed a 22-item Marijuana Withdrawal Symptom checklist based on their most recent period of marijuana abstinence. FINDINGS: The majority (57%) indicated that they had experienced > or = six symptoms of at least moderate severity and 47% experienced > or = four symptoms rated as severe. Withdrawal severity was greater in those with psychiatric symptomatology and more frequent marijuana use. CONCLUSIONS: This study provides further support for a cluster of withdrawal symptoms experienced following cessation of regular marijuana use. The affective and behavioral symptoms reported were consistent with those observed in previous laboratory and interview studies. Since withdrawal symptoms are frequently a target for clinical intervention with other substances of abuse, this may also be appropriate for marijuana.
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“six-session CBT produced superior results when compared with a single CBT session in another clinical trial 25.”
From Psychosocial and pharmacological interventions for the treatment of cannabis use disorder (2018) · cites this paper as [25]
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Ford, B. (2010) · Scholars Commons (Wilfrid Laurier University)
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Rubat, É. (2008) · OpenGrey (Institut de l'Information Scientifique et Technique)
PROSPECTIVE STUDY OF CANNABIS WITHDRAWAL IN CANNABIS-USING ADOLESCENTS
Dawes, M. A., Richard, D. M., Mathias, C. W., et al. (2008) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31817eed64
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Cannabisabhängigkeit bei Jugendlichen und jungen Erwachsenen
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The Science of Marijuana and the Brain
Cermak, T. L. (2020)
Effects of Cannabis Abstinence on Symptoms and Cognition in Major Depressive Disorder
Lucatch, A. M. (2019) · TSpace (University of Toronto)
Potential Pharmacotherapies for Cannabis Dependence
Hart, C. L., & Shytle, R. D. (2010) · Springer eBooks · doi:10.1007/978-1-4419-0338-9_53
Geschwinde, T. (2018) · Springer eBooks · doi:10.1007/978-3-662-56275-8_1
Geschwinde, T. (2012) · Springer eBooks · doi:10.1007/978-3-642-30163-6_1
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Zvolensky, M. J., Kauffman, B. Y., Garey, L., et al. (2022) · Addictive Behaviors · doi:10.1016/j.addbeh.2022.107344
Bègue, L. (2014) · Dunod eBooks · doi:10.3917/dunod.begue.2014.01.0131
Lejoyeux, M., Adès, J., Aubin, H., Auriacombe, M., Balester-Mouret, S., Batel, P., Beck, F., Benyamina, A., Berlin, I., Bétizeau, A., et al. (2009) · Elsevier eBooks · doi:10.1016/b978-2-294-70316-4.00011-4
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Abus et dépendance au cannabis à l'adolescence
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Chapter 4. Cannabis and Cannabinoids
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“Finally, while the CWC provides valuable symptom data, it may not fully capture the complexity of the withdrawal experience, particularly among individual ’ s dependent on multiple substances.”
Influentialde Bode, N., Kroon, E., Hsieh, J. H., & Cousijn, J. (2025) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2025.152659
Macedo, I., Pasion, R., Magalhães, A., & Barbosa, F. (2026) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.a.2489
Matheson, J., Zakala, C., Zhao, S., Battistuzzi, A., Nette, A., Foll, B. L., Wickens, C. M., Wang, W., Chen, S., & Ciano, P. D. (2026) · Drug and Alcohol Dependence Reports · doi:10.1016/j.dadr.2026.100432
“The study visit included a urine drug screen, a Breathalyzer test, the Marijuana With-drawal Checklist (MWC) (Budney, Novy, and Hughes, 1999; Budney et al., 2003), and the Pittsburgh Sleep Quality Index (Buysse et al., 1989).”
Saura, J., Feliu, A., Enríquez, M., Tutusaus, X. R., Ballbè, M., Fu, M., Segura, L., Fernández, E., & Martínez, C. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1744004
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Metadata
- Authors
- Budney, A. J., Novy, P. L., & Hughes, J. R.
- Affiliations
- University of Vermont (US)
- Venue
- Addiction
- Publisher
- Wiley
- Published
- 1999-09
- Volume
- 94
- Issue
- 9
- Pages
- 1311-1322
- ISSN
- 0965-2140 (ISSN-L)
- 1360-0443
- OpenAlex
- W2119758521
- Cited by
- 348
- References
- 0
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 11 · 2023: 15 · 2022: 12 · 2021: 11 · 2020: 18 · 2019: 12 · 2018: 22 · 2017: 15 · 2016: 10 · 2015: 17 · 2014: 15 · 2013: 11 · 2012: 16
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addiction (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r29da008655-05)
- National Institute on Drug Abuse (R-29DA08655)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Keywords
- cannabis use disorder, withdrawal symptom severity, psychiatric comorbidity, addiction treatment, cannabis
- MeSH terms
- Adult, Analysis of Variance, Marijuana Abuse, Female, Humans, Male, Patient Acceptance of Health Care, Regression Analysis, Stress, Psychological, Substance Withdrawal Syndrome
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