The DOI matches its Crossref record; 40 of the 41 references it cites were found in a registry or an index.
Does retention matter? Treatment duration and improvement in drug use
Abstract
Aim This study examines whether there is a minimum threshold, continuous or non‐linear relationship between the duration of addiction treatment and improvements in drug use. Design Longitudinal cohort study of 62 drug treatment units and 4005 clients in the US National Treatment Improvement Evaluation Study, fielded from 1993 to 1995. Subjects Baseline and 1‐year follow‐up interviews with clients in methadone maintenance, out‐patient non‐methadone, short‐term residential and long‐term residential treatment programs. Measures Improvement in drug use is the difference between the client‐reported peak frequency of drug use (in days per month) in the year prior to the baseline interview minus the peak frequency in the year after discharge. Primary drug, and overall use of the major illicit drugs (heroin, cocaine powder, crack cocaine, and marijuana) are considered separately. Results Controlling for multiple factors, treatment duration had a positive linear relationship with primary drug use improvement among methadone clients and an inverted‐U‐shaped relationship with overall and primary drug use improvements among out‐patient and long‐term residential clients. Improvement with longer duration is greatest for long‐term residential clients. Conclusions Contrary to previous arguments for a sharp retention threshold for onset of treatment effects, we find smooth curves relating treatment duration to drug use improvements in methadone maintenance, out‐patient non‐methadone and long‐term residential modalities. These relationships are effectively linear for durations typically observed in single treatment episodes, but unusually long retention in out‐patient non‐methadone and long‐term residential units appear steadily less predictive of improvement.
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“dropout from opioid substitution treatment is associated with relapse and an increased risk of overdose and death (Clausen et al., 2008; Zhang et al., 2003).”
From Feasibility and acceptability of mindful recovery opioid use care continuum (M-ROCC): A concurrent mixed methods study (2021) · cites this paper as Zhang et al., 2003
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Strang, J., Volkow, N. D., Degenhardt, L., Hickman, M., Johnson, K., Koob, G. F., Marshall, B. D. L., Tyndall, M., & Walsh, S. L. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0137-5 · Cited by 639
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Medication Treatment of Opioid Use Disorder
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Metadata
- Authors
- Zhang, Z., Friedmann, P. D., & Gerstein, D. R.
- Affiliations
- University of Chicago (US)
- Brown University (US)
- Corresponding author
- Zhang, Zhiwei
- Venue
- Addiction
- Publisher
- Wiley
- Published
- 2003-05
- Volume
- 98
- Issue
- 5
- Pages
- 673-684
- ISSN
- 0965-2140 (ISSN-L)
- 1360-0443
- OpenAlex
- W2007620075
- Cited by
- 314
- References
- 41
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 13 · 2023: 11 · 2022: 12 · 2021: 22 · 2020: 13 · 2019: 18 · 2018: 9 · 2017: 13 · 2016: 17 · 2015: 15 · 2014: 18 · 2013: 23 · 2012: 12
- FWCI
- 7.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addiction (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Substance Abuse and Mental Health Services Administration
- National Institute on Drug Abuse (R01DA013615, R01-DA13615)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- treatment duration, treatment retention, addiction treatment, methadone maintenance treatment, outpatient care, residential treatment, heroin use, cocaine use, cannabis use, treatment effects
- MeSH terms
- Adolescent, Adult, Aged, Ambulatory Care, Analysis of Variance, Female, Humans, Longitudinal Studies, Male, Methadone, Middle Aged, Narcotics, Patient Compliance, Residential Treatment, Time Factors, Treatment Outcome, Substance-Related Disorders
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