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Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise
Abstract
On two occasions, seven male endurance-trained cyclists performed exhaustive exercise on a cycle ergometer in the morning after they had performed a bout of exercise the preceding evening in an attempt to lower the muscle glycogen stores. The subjects exercised at a work rate corresponding to approximately 70% of their maximal oxygen uptake for 60 min, followed by another 20 min of maximal exercise. During exercise the subjects were given either a solution of branched-chain amino acids (BCAAs) or flavoured water (placebo). Every 10 min during exercise the subjects rated their perceived exertion and mental fatigue on two different Borg scales. During the 60 min exercise at a given work rate the subjects ratings of perceived exertion when they were given BCAAs were 7% lower, and their ratings of mental fatigue were 15% lower than when they were given placebo. In addition, the performance in the colour task of Stroops Colour Word Test performed after exercise was improved when BCAAs had been ingested during exercise, compared with the results from the placebo trial. There was no difference in the physical performance between the two trials measured as the amount of work done during the last 20 min of exercise when the subjects performed at their maximum. The plasma concentration ratio of free tryptophan/BCAAs, which increased by 45% during exercise and by 150% 5 min after exercise in the placebo trial, remained unchanged or even decreased when BCAAs were ingested.
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“Indeed, athletes showed reduced effort perceptions when BCAAs were supplemented during submaximal cycle exercise performed in a glycogen-depleted state [111].”
From International Society of Sports Nutrition Position Stand: nutritional considerations for single-stage ultra-marathon training and racing (2019) · cites this paper as [111]
In the citing paper
“The main findings of these extracted studies reveal that BCAA intake caused a substantial improvement in BCAAs:tryptophan ratio [21,27] and immune response [27,38,39].”
From Oral Branched-Chain Amino Acids Supplementation in Athletes: A Systematic Review (2022) · cites this paper as [21]
In the citing paper
“Ratings of perceived exertion and mental fatigue were significantly reduced in the BCAA group among seven endurance cyclists [21]”
From Oral Branched-Chain Amino Acids Supplementation in Athletes: A Systematic Review (2022) · cites this paper as [21]
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“Among them, BCAAs are essential amino compounds of leucine, isoleucine, and valine (8) that may decrease some biochemical markers related to muscle soreness (9), stimulate recovery of muscle protein synthesis (10), reduce central fatigue (11), and improve physical performance (12).”
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Metadata
- Authors
- BLOMSTRAND, E., HASSMÉN, P., EK, S., EKBLOM, B., & NEWSHOLME, E. A.
- Affiliations
- Stockholm University (SE)
- Karolinska Institutet (SE)
- University of Oxford (GB)
- Corresponding author
- BLOMSTRAND, E.
- Venue
- Acta Physiologica Scandinavica
- Publisher
- Wiley
- Published
- 1997-01
- Volume
- 159
- Issue
- 1
- Pages
- 41-49
- ISSN
- 0001-6772 (ISSN-L)
- 1365-201X
- OpenAlex
- W2045788598
- Cited by
- 168
- References
- 0
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 7 · 2019: 8 · 2018: 7 · 2017: 6 · 2016: 4 · 2015: 8 · 2014: 7 · 2013: 6 · 2012: 7
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Physiologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Keywords
- branched-chain amino acids, perceived exertion, mental fatigue, endurance exercise, exercise performance, muscle glycogen depletion, ergogenic aids
- MeSH terms
- Adult, Amino Acids, Branched-Chain, Blood Glucose, Physical Exertion, Humans, Male, Task Performance and Analysis, Exercise
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