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Cited by 73

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The effect of decaffeination of coffee on gastro-oesophageal reflux in patients with reflux disease

Pehl, C., Pfeiffer, A., Wendl, B., Kaess, H.·1997·Alimentary Pharmacology & Therapeutics
DOI 10.1046/j.1365-2036.1997.00161.x
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Abstract

Background: Patients with reflux disease often complain of heartburn after ingestion of coffee. Induction of gastro‐oesophageal reflux has been demonstrated by pH‐metry following the intake of coffee in healthy volunteers. The reflux was reduced when the coffee had undergone a decaffeination process. The aim of this study was to investigate the effect of decaffeination of coffee on reflux in patients with reflux disease. Methods: Seventeen reflux patients underwent two oesophageal 3‐h pH measurements. The patients received, in a double‐blind study design in a randomized order, 300 mL of either regular or decaffeinated coffee together with a standardized breakfast. The fraction time oesophageal pH < 4 was calculated during the three postprandial hours. Results: For regular coffee the fraction time was calculated to a median of 17.9% with a range of 0.7–56.6%. The fraction time was significantly reduced to 3.1% (0–49.9%) after ingestion of decaffeinated coffee. Conclusion: The amount of gastro‐oesophageal reflux induced by the intake of regular coffee in patients with reflux disease can be reduced by the decaffeination of coffee.

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Research works printed but not linked: 18

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Metadata

Authors
Pehl, C., Pfeiffer, A., Wendl, B., & Kaess, H.
Venue
Alimentary Pharmacology & Therapeutics
Publisher
Wiley
Published
1997-06
Volume
11
Issue
3
Pages
483-486
ISSN
  • 0269-2813
  • 1365-2036
DOI
10.1046/j.1365-2036.1997.00161.x
Cited by
73
References
2
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 2357 d)

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