The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The effect of decaffeination of coffee on gastro-oesophageal reflux in patients with reflux disease
Abstract
Background: Patients with reflux disease often complain of heartburn after ingestion of coffee. Induction of gastro‐oesophageal reflux has been demonstrated by pH‐metry following the intake of coffee in healthy volunteers. The reflux was reduced when the coffee had undergone a decaffeination process. The aim of this study was to investigate the effect of decaffeination of coffee on reflux in patients with reflux disease. Methods: Seventeen reflux patients underwent two oesophageal 3‐h pH measurements. The patients received, in a double‐blind study design in a randomized order, 300 mL of either regular or decaffeinated coffee together with a standardized breakfast. The fraction time oesophageal pH < 4 was calculated during the three postprandial hours. Results: For regular coffee the fraction time was calculated to a median of 17.9% with a range of 0.7–56.6%. The fraction time was significantly reduced to 3.1% (0–49.9%) after ingestion of decaffeinated coffee. Conclusion: The amount of gastro‐oesophageal reflux induced by the intake of regular coffee in patients with reflux disease can be reduced by the decaffeination of coffee.
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“In contrast, one review and meta-analysis of 40 studies [48] and 11 single studies reported an association between coffee consumption and GERD [35,41,43,62,63,64,65,66,67,68,69].”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [63]
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Cites
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Cited by
Coffee and Gastrointestinal Function: Facts and Fiction: A Review
J. Boekema, M. S. (1999) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655299750025525 · Cited by 164
Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update
Nehlig, A. (2022) · Nutrients · doi:10.3390/nu14020399 · Cited by 158
Acidity and Antioxidant Activity of Cold Brew Coffee
Rao, N. Z., & Fuller, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-34392-w · Cited by 144
Food and Gastroesophageal Reflux Disease
Surdea-Blaga, T., Negrutiu, D. E., Palage, M., & Dumitrascu, D. L. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867324666170515123807 · Cited by 101
Kim, J., Oh, S.-W., Myung, S.-K., Kwon, H., Lee, C., Yun, J. M., Lee, H. K., & The Korean Meta-analysis (KORMA) Study Group (2014) · Diseases of the Esophagus · doi:10.1111/dote.12099 · Cited by 88
Metadata
- Authors
- Pehl, C., Pfeiffer, A., Wendl, B., & Kaess, H.
- Venue
- Alimentary Pharmacology & Therapeutics
- Publisher
- Wiley
- Published
- 1997-06
- Volume
- 11
- Issue
- 3
- Pages
- 483-486
- ISSN
- 0269-2813
- 1365-2036
- Cited by
- 73
- References
- 2
- Language
- en
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