Health-related quality of life among patients with facial acne − assessment of a new acne-specific questionnaire: QoL and facial acne
Abstract
The psychosocial effects of facial acne are well accepted but until recently few validated instruments existed which were suitable for use in clinical trials. The aim of this study was to assess measurement characteristics (reproducibility, correlation with acne severity, and sensitivity to detect change after acne therapy) of a new acne-specific quality of life instrument, the Acne-QoL. We found that the Acne-QoL is reliable, valid and able to distinguish differences across severity groups and improvement over 16 weeks of standard therapy. The use of the Acne-QoL should aid physicians in understanding the impact of facial acne on young adults, and may be useful in assessing therapeutic effects in acne clinical trials.
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The Acne-Specific Quality of Life questionnaire has four domains and a higher score in any domain indicates improved health-related quality of life.
“Participants also completed an Acne-Specific Quality of Life (Acne-QoL) questionnaire covering four domains (self-perception, role-emotional, role-social, and acne symptoms) at baseline and week 12; a higher score in any domain indicates improved health-related quality of life [16].”
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- Authors
- Martin, A. R., Lookingbill, D. P., Botek, A., Light, J., Thiboutot, D., & Girman, C. J.
- Affiliations
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- Mayo Clinic (US)
- Pennsylvania State University (US)
- Corresponding author
- Martin, A. R.
- ORCID
- Thiboutot, D.
- Venue
- Clinical and Experimental Dermatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-07
- Volume
- 26
- Issue
- 5
- Pages
- 380-385
- ISSN
- 0307-6938 (ISSN-L)
- OpenAlex
- W2025655544
- Cited by
- 157
- References
- 23
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 5 · 2023: 7 · 2022: 10 · 2021: 28 · 2020: 9 · 2019: 8 · 2018: 9 · 2017: 5 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 2 · 2012: 6
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Clinical and Experimental Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Keywords
- facial acne, health-related quality of life, acne severity, measurement reliability, questionnaire validation, sensitivity to change, acne treatment, young adults
- MeSH terms
- Acne Vulgaris, Adolescent, Adult, Female, Health Surveys, Humans, Male, Quality of Life, Surveys and Questionnaires, Self Concept
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