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Mechanisms of antimicrobial activity of calcium hydroxide: a critical review
Abstract
Literature review The primary function of calcium hydroxide as a routine intracanal medicament is to provide antimicrobial activity. However, the mechanisms of antimicrobial activity of calcium hydroxide are not well known. Physicochemical properties of this substance may limit its effectiveness in disinfecting the entire root canal system. In addition, calcium hydroxide is not effective against all bacterial species found in root canal infections. Association with other medicaments may enhance the efficacy of the intracanal medication in eliminating residual bacteria in the root canal system.
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Cites
DNA damage and oxygen radical toxicity
Imlay, J. A., & Linn, S. (1988) · Science · doi:10.1126/science.3287616 · Cited by 1,974
Cited by
Passive ultrasonic irrigation of the root canal: a review of the literature
Van Der Sluis, L. W. M., Versluis, M., Wu, M. K., & Wesselink, P. R. (2007) · International Endodontic Journal · doi:10.1111/j.1365-2591.2007.01243.x · Cited by 849
Properties and applications of calcium hydroxide in endodontics and dental traumatology
Mohammadi, Z., & Dummer, P. M. H. (2011) · International Endodontic Journal · doi:10.1111/j.1365-2591.2011.01886.x · Cited by 830
Regenerative endodontics: a comprehensive review
Kim, S. G., Malek, M., Sigurdsson, A., Lin, L. M., & Kahler, B. (2018) · International Endodontic Journal · doi:10.1111/iej.12954 · Cited by 523
Choudhury, R. R., Gohil, J. M., Mohanty, S., & Nayak, S. K. (2018) · Journal of Materials Chemistry A · doi:10.1039/c7ta08627j · Cited by 420
Peters, L. B., & Wesselink, P. R. (2002) · International Endodontic Journal · doi:10.1046/j.1365-2591.2002.00541.x · Cited by 320
Metadata
- Authors
- Siqueira, J. F., & Lopes, H. P.
- Venue
- International Endodontic Journal
- Publisher
- Wiley
- Published
- 1999-09
- Volume
- 32
- Issue
- 5
- Pages
- 361-369
- ISSN
- 0143-2885 (ISSN-L)
- 1365-2591
- OpenAlex
- W2167269512
- Cited by
- 966
- References
- 1
- FWCI
- 12.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Siqueira, J. F., & Lopes, H. P. (1999). Mechanisms of antimicrobial activity of calcium hydroxide: a critical review. International Endodontic Journal. https://doi.org/10.1046/j.1365-2591.1999.00275.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.