The DOI matches its Crossref record.
Genetic diversity of vaginal lactobacilli from women in different countries based on 16S rRNA gene sequences
Abstract
AIMS: Lactobacilli are widely distributed in food and the environment, and some colonize the human body as commensal bacteria. The aim of this study was to determine the species of lactobacilli that colonize the vagina and compare them with those found in food and the environment. METHODS AND RESULTS: Thirty-five Lactobacillus strains from women from seven countries were isolated, and sequences from 16S rRNA genes were determined and compared with existing data in GenBank. A phylogenetic tree was achieved using the Neighbour-Joining method based on the analysis of 1465 nucleotides. The results showed that most vaginal isolates were L. crispatus, L. jensenii and L. gasseri. Some were L. vaginalis, L. fermentum, L. mucosae, L. paracasei and L. rhamnosus. Two isolates from a native American woman displayed distinct branches, indicating novel phylotypes. Few vaginal isolates matched food or environmental Lactobacillus species. CONCLUSIONS: Most women worldwide were colonized by three common Lactobacillus species: L. crispatus, L. jensenii and L. gasseri. SIGNIFICANCE AND IMPACT OF THE STUDY: Knowledge of vaginal Lactobacillus species richness and distribution in women worldwide may lead to the design of better probiotic products as bacterial replacement therapy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Critical Evaluation of Two Primers Commonly Used for Amplification of Bacterial 16S rRNA Genes
Frank, J. A., Reich, C. I., Sharma, S., Weisbaum, J. S., Wilson, B. A., & Olsen, G. J. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02272-07 · Cited by 1,912
Evidence that the endometrial microbiota has an effect on implantation success or failure
Moreno, I., Codoñer, F. M., Vilella, F., Valbuena, D., Martinez-Blanch, J. F., Jimenez-Almazán, J., Alonso, R., Alamá, P., Remohí, J., Pellicer, A., et al. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.09.075 · Cited by 868
Romero, R., Hassan, S. S., Gajer, P., Tarca, A. L., Fadrosh, D. W., Nikita, L., Galuppi, M., Lamont, R. F., Chaemsaithong, P., Miranda, J., et al. (2014) · Microbiome · doi:10.1186/2049-2618-2-4 · Cited by 852
Susceptibility of Lactobacillus spp. to antimicrobial agents
Danielsen, M., & Wind, A. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(02)00254-4 · Cited by 559
Stapleton, A. E., Au-Yeung, M., Hooton, T. M., Fredricks, D. N., Roberts, P. L., Czaja, C. A., Yarova-Yarovaya, Y., Fiedler, T., Cox, M., & Stamm, W. E. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir183 · Cited by 484
Metadata
- Authors
- Pavlova, S. I., Kilic, A. O., Kilic, S. S., So, J.-S., Nader-Macias, M. E., Simoes, J. A., & Tao, L.
- Venue
- Journal of Applied Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-03
- Volume
- 92
- Issue
- 3
- Pages
- 451-459
- ISSN
- 1364-5072 (ISSN-L)
- 1365-2672
- OpenAlex
- W2027548763
- Cited by
- 233
- References
- 0
- FWCI
- 4.91
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Genetic diversity of vaginal lactobacilli from women in different countries based on 16S rRNA gene sequences. https://app.cochat.ai/papers/10.1046/j.1365-2672.2002.01547.x
- The paper
- Pavlova, S. I., Kilic, A. O., Kilic, S. S., So, J.-S., Nader-Macias, M. E., Simoes, J. A., & Tao, L. (2002). Genetic diversity of vaginal lactobacilli from women in different countries based on 16S rRNA gene sequences. Journal of Applied Microbiology. https://doi.org/10.1046/j.1365-2672.2002.01547.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
