The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Tissue shrinkage and unbiased stereological estimation of particle number and size*
Abstract
This paper is a review of the stereological problems related to the unbiased estimation of particle number and size when tissue deformation is present. The deformation may occur during the histological processing of the tissue. It is especially noted that the widely used optical disector may be biased by dimensional changes in the z‐axis, i.e. the direction perpendicular to the section plane. This is often the case when frozen sections or vibratome sections are used for the stereological measurements. The present paper introduces new estimators to be used in optical fractionator and optical disector designs; the first is, as usual, the simplest and most robust. Finally, it is stated that when tissue deformation only occurs in the z‐direction, unbiased estimation of particle size with several estimators is possible.
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West, M. J., Slomianka, L., & Gundersen, H. J. G. (1991) · The Anatomical Record · doi:10.1002/ar.1092310411 · Cited by 2,994
Self-citationThe efficiency of systematic sampling in stereology—reconsidered
GUNDERSEN, H. J. G., JENSEN, E. B. V., KIÊU, K., & NIELSEN, J. (1999) · Journal of Microscopy · doi:10.1046/j.1365-2818.1999.00457.x · Cited by 1,317
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Metadata
- Authors
- Dorph‐Petersen, K. ‐., Nyengaard, J. R., & Gundersen, H. J. G.
- Venue
- Journal of Microscopy
- Publisher
- Wiley
- Published
- 2001-12
- Volume
- 204
- Issue
- 3
- Pages
- 232-246
- ISSN
- 0022-2720 (ISSN-L)
- 1365-2818
- OpenAlex
- W2037367554
- Cited by
- 539
- References
- 2
- FWCI
- 28.79
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dorph‐Petersen, K. ‐., Nyengaard, J. R., & Gundersen, H. J. G. (2001). Tissue shrinkage and unbiased stereological estimation of particle number and size*. Journal of Microscopy. https://doi.org/10.1046/j.1365-2818.2001.00958.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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