The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Molecular switches — the ON and OFF of bacterial phase variation
Open accessAbstract
The expression of most bacterial genes is controlled at the level of transcription via promoter control mechanisms that permit a graded response. However, an increasing number of bacterial genes are found to exhibit an ‘all‐or‐none’ control mechanism that adapts the bacterium to more than one environment. One such mechanism is phase variation, traditionally defined as the high‐frequency ON↔OFF switching of phenotype expression. Phase variation events are usually random, but may be modulated by environmental conditions. The mechanisms of phase variation events and their significance within the microbial community are discussed here.
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Citations
Cites
Short-sequence DNA repeats in prokaryotic genomes
van Belkum, A., Scherer, S., van Alphen, L., & Verbrugh, H. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.2.275-293.1998 · Cited by 737
Cited by
Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation
Drenkard, E., & Ausubel, F. M. (2002) · Nature · doi:10.1038/416740a · Cited by 997
Microbial Cell Individuality and the Underlying Sources of Heterogeneity
Avery, S. V. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1460 · Cited by 521
Metabolic specialization associated with phenotypic switching in Candida albicans
Lan, C.-Y., Newport, G., Murillo, L. A., Jones, T., Scherer, S., Davis, R. W., & Agabian, N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.232566499 · Cited by 275
Le Flèche, P., Hauck, Y., Onteniente, L., Prieur, A., Denoeud, F., Ramisse, V., Sylvestre, P., Benson, G., Ramisse, F., & Vergnaud, G. (2001) · BMC Microbiology · doi:10.1186/1471-2180-1-2 · Cited by 270
Tracing isolates of bacterial species by multilocus variable number of tandem repeat analysis (MLVA)
Van Belkum, A. (2007) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2006.00173.x · Cited by 203
Metadata
- Authors
- Henderson, I. R., Owen, P., & Nataro, J. P.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 1999-09
- Volume
- 33
- Issue
- 5
- Pages
- 919-932
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2049415064
- Cited by
- 501
- References
- 1
- FWCI
- 8.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Henderson, I. R., Owen, P., & Nataro, J. P. (1999). Molecular switches — the ON and OFF of bacterial phase variation. Molecular Microbiology. https://doi.org/10.1046/j.1365-2958.1999.01555.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
