The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The outer membrane protein, Antigen 43, mediates cell‐to‐cell interactions within Escherichia coli biofilms
Open accessAbstract
Transcription of the agn43 locus, which specifies an outer membrane protein of Escherichia coli, is regulated in a phase‐variable fashion by the OxyR–DNA binding protein and Dam methylase. Despite its well‐characterized regulation, the function of Ag43 has remained elusive until now. Previous studies indicated that Ag43 mediates autoaggregation of certain strains of E. coli in liquid culture. Given this phenotype, we examined the role of Ag43 in biofilm formation. Here, we report that Ag43 contributes to E. coli biofilm formation in glucose‐minimal medium, but not in Luria–Bertani broth. In addition, we show that flagellar‐mediated motility is required for biofilm formation in both rich and minimal environments. Altogether, our results suggest that E. coli uses both common and specific gene sets for the development of biofilms under various growth conditions.
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Citations
Cites
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167
Cited by
Hobley, L., Harkins, C., MacPhee, C. E., & Stanley-Wall, N. R. (2015) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuv015 · Cited by 581
“It was first shown to be important for biofilm formation in the E. coli strain W3110, where it is required for wild-type levels of submerged biofilm formation in glucose-minimal medium (Danese et al. 2000).”
BackgroundInfluentialItoh, Y., Wang, X., Hinnebusch, B. J., Preston, J. F., & Romeo, T. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.1.382-387.2005 · Cited by 322
Chemotaxis towards autoinducer 2 mediates autoaggregation in Escherichia coli
Laganenka, L., Colin, R., & Sourjik, V. (2016) · Nature Communications · doi:10.1038/ncomms12984 · Cited by 218
Ulett, G. C., Valle, J., Beloin, C., Sherlock, O., Ghigo, J.-M., & Schembri, M. A. (2007) · Infection and Immunity · doi:10.1128/iai.01952-06 · Cited by 214
Heras, B., Totsika, M., Peters, K. M., Paxman, J. J., Gee, C. L., Jarrott, R. J., Perugini, M. A., Whitten, A. E., & Schembri, M. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1311592111 · Cited by 141
Metadata
- Authors
- Danese, P. N., Pratt, L. A., Dove, S. L., & Kolter, R.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2000-07
- Volume
- 37
- Issue
- 2
- Pages
- 424-432
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2020920408
- Cited by
- 345
- References
- 1
- FWCI
- 4.51
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: The outer membrane protein, Antigen 43, mediates cell‐to‐cell interactions within Escherichia coli biofilms. https://app.cochat.ai/papers/10.1046/j.1365-2958.2000.02008.x
- The paper
- Danese, P. N., Pratt, L. A., Dove, S. L., & Kolter, R. (2000). The outer membrane protein, Antigen 43, mediates cell‐to‐cell interactions within Escherichia coli biofilms. Molecular Microbiology. https://doi.org/10.1046/j.1365-2958.2000.02008.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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