The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
The RPM1 plant disease resistance gene facilitates a rapid and sustained increase in cytosolic calcium that is necessary for the oxidative burst and hypersensitive cell death
Abstract
Summary: Early events occurring during the hypersensitive resistance response (HR) were examined using the avrRpm1/RPM1 gene‐for‐gene interaction in Arabidopsis challenged by Pseudomonas syringae pv. tomato. Increases in cytosolic Ca 2+ were measured in whole leaves using aequorin‐mediated bioluminescence. During the HR a sustained increase in Ca 2+ was observed which was dependent on the presence of both a functional RPM1 gene product and delivery of the cognate avirulence gene product AvrRpm1. The sequence‐unrelated avirulence gene avrB, which also interacts with RPM1, generated a significantly later but similarly prolonged increase in cytosolic Ca 2+. Accumulation of H 2 O 2 at reaction sites, as revealed by electron microscopy, occurred within the same time frame as the changes in cytosolic Ca 2+. The NADPH oxidase inhibitor diphenylene iodonium chloride did not affect the calcium signature, but did block H 2 O 2 accumulation and the HR. By contrast, the calcium‐channel blocker LaCl 3 suppressed the increase in cytosolic Ca 2+ as well as H 2 O 2 accumulation and the HR, placing calcium elevation upstream of the oxidative burst.
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Cites
Floral dip: a simplified method forAgrobacterium‐mediated transformation ofArabidopsis thaliana
Clough, S. J., & Bent, A. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00343.x · Cited by 21,934
Two simple media for the demonstration of pyocyanin and fluorescin.
Eo, K., WARD, M. K., & De, R. (1954) · PubMed · Cited by 5,234
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
Miyawaki, A., Llopis, J., Heim, R., McCaffery, J. M., Adams, J. A., Ikura, M., & Tsien, R. Y. (1997) · Nature · doi:10.1038/42264 · Cited by 3,248
THE OXIDATIVE BURST IN PLANT DISEASE RESISTANCE
Lamb, C., & Dixon, R. A. (1997) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.48.1.251 · Cited by 3,213
Current Status of the Gene-For-Gene Concept
Flor, H. H. (1971) · Annual Review of Phytopathology · doi:10.1146/annurev.py.09.090171.001423 · Cited by 3,185
Zou, H., Henzel, W. J., Liu, X., Lutschg, A., & Wang, X. (1997) · Cell · doi:10.1016/s0092-8674(00)80501-2 · Cited by 3,145
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
Levine, A., Tenhaken, R., Dixon, R., & Lamb, C. (1994) · Cell · doi:10.1016/0092-8674(94)90544-4 · Cited by 2,766
An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9
Zou, H., Li, Y., Liu, X., & Wang, X. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.17.11549 · Cited by 2,090
Resistance gene-dependent plant defense responses.
Hammond-Kosack, K. E., & Jones, J. D. (1996) · The Plant Cell · doi:10.1105/tpc.8.10.1773 · Cited by 1,752
PLANT DISEASE RESISTANCE GENES
Hammond-Kosack, K. E., & Jones, J. D. G. (1997) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.48.1.575 · Cited by 1,188
Cited by
WHITE, P. J. (2003) · Annals of Botany · doi:10.1093/aob/mcg164 · Cited by 2,381
PTI-ETI crosstalk: an integrative view of plant immunity
Yuan, M., Ngou, B. P. M., Ding, P., & Xin, X.-F. (2021) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2021.102030 · Cited by 915
The plant immune system: From discovery to deployment
Jones, J. D. G., Staskawicz, B. J., & Dangl, J. L. (2024) · Cell · doi:10.1016/j.cell.2024.03.045 · Cited by 544
Homeostasis-altering molecular processes as mechanisms of inflammasome activation
Liston, A., & Masters, S. L. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2016.151 · Cited by 459
Signal transmission in the plant immune response
Nürnberger, T., & Scheel, D. (2001) · Trends in Plant Science · doi:10.1016/s1360-1385(01)02019-2 · Cited by 323
Metadata
- Authors
- Grant, M., Brown, I., Adams, S., Knight, M., Ainslie, A., & Mansfield, J.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2000-08
- Volume
- 23
- Issue
- 4
- Pages
- 441-450
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W2071041070
- Cited by
- 503
- References
- 45
- FWCI
- 29.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Grant, M., Brown, I., Adams, S., Knight, M., Ainslie, A., & Mansfield, J. (2000). The RPM1 plant disease resistance gene facilitates a rapid and sustained increase in cytosolic calcium that is necessary for the oxidative burst and hypersensitive cell death. The Plant Journal. https://doi.org/10.1046/j.1365-313x.2000.00804.x
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