Comparison of Etest with the broth microdilution method in susceptibility testing of yeast isolates against four antifungals
Abstract
A comparative evaluation of the Etest and the broth microdilution methods for antifungal susceptibility testing of 102 clinical yeast isolates against amphotericin B, fluconazole, itraconazole, and ketoconazole was conducted. The agreements between the Etest and the broth microdilution methods were 93.1% for amphotericin B 85.2% for ketoconazole, 82.3% for itraconazole and 79.4% for fluconazole. These results suggest that the Etest approach to antifungal susceptibility testing may be a viable alternative to the NCCLS reference methods for testing yeasts, but that further evaluations are needed.
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Nedret Koc et al. reported three C. glabrata isolates with MICs of ≥8 μg ml−1.
“For instance, Nedret Koc et al. [94] reported three C. glabrata isolates with MICs of ≥8 µg ml−1.”
From Candida glabrata: pathogenicity and resistance mechanisms for adaptation and survival (2021) · cites this paper as [94]
Cites
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Candida glabrata: pathogenicity and resistance mechanisms for adaptation and survival
Hassan, Y., Chew, S. Y., & Than, L. T. L. (2021) · Journal of Fungi · doi:10.3390/jof7080667 · Cited by 170 · see citing works
- Authors
- Nedret Koç, A., Gökahmetògˇlu, S., & Ògˇuzkaya, M.
- Affiliations
- Erciyes University (TR)
- Venue
- Mycoses
- Publisher
- Wiley
- Published
- 2000-09-05
- Volume
- 43
- Issue
- 7-8
- Pages
- 293-297
- ISSN
- 0027-5557 (ISSN-L)
- 0933-7407
- 1439-0507
- OpenAlex
- W2169476905
- Cited by
- 22
- References
- 14
- Citations by year
- 2025: 1 · 2021: 2 · 2017: 1 · 2015: 2 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mycoses (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Keywords
- E-test, broth microdilution, antifungal susceptibility testing, clinical yeast isolates, amphotericin B, fluconazole, itraconazole, ketoconazole, measurement agreement
- MeSH terms
- Antifungal Agents, Candida, Microbial Sensitivity Tests, Rhodotorula
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