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Cited by 530

The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.

Intestinal barrier: An interface between health and disease

Open access
FARHADI, ASHKAN, BANAN, ALI, FIELDS, JEREMY, KESHAVARZIAN, ALI·2003·Journal of Gastroenterology and Hepatology

Abstract

Abstract The intestine constitutes the largest interface between a person and his or her environment, and an intact intestinal barrier is thus essential in maintaining health and preventing tissue injury and several diseases. The intestinal barrier has various immunological and non‐immunological components. The epithelial barrier is one of the most important non‐immunological components. Hyperpermeability of this barrier is believed to contribute to the pathogenesis of several gastrointestinal disorders including inflammatory bowel disease, celiac disease and food allergy. Hence, assessing barrier integrity is of the utmost importance. One of the more quantitative gauges for this assessment is transepithelial permeability of various molecular probes, among which sugars are commonly used. Measures of intestinal permeability might also be useful as markers for assessment of prognosis and follow up in various gastrointestinal disorders. The present article is a review of the normal and abnormal functioning of the intestinal barrier, the diseases that can result from loss of barrier integrity, and some promising agents and strategies for restoring barrier normality and integrity. © 2003 Blackwell Publishing Asia Pty Ltd

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Crossref · 10.1046/j.1440-1746.2003.03032.x

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Metadata

Authors
FARHADI, A., BANAN, A., FIELDS, J., & KESHAVARZIAN, A.
Venue
Journal of Gastroenterology and Hepatology
Publisher
Wiley
Published
2003-04-15
Volume
18
Issue
5
Pages
479-497
ISSN
  • 0815-9319 (ISSN-L)
  • 1440-1746
OpenAlex
W1984172120
Cited by
530
References
158
FWCI
11.09
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Intestinal barrier: An interface between health and disease. https://app.cochat.ai/papers/10.1046/j.1440-1746.2003.03032.x
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FARHADI, A., BANAN, A., FIELDS, J., & KESHAVARZIAN, A. (2003). Intestinal barrier: An interface between health and disease. Journal of Gastroenterology and Hepatology. https://doi.org/10.1046/j.1440-1746.2003.03032.x

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