The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.
Intestinal barrier: An interface between health and disease
Open accessAbstract
Abstract The intestine constitutes the largest interface between a person and his or her environment, and an intact intestinal barrier is thus essential in maintaining health and preventing tissue injury and several diseases. The intestinal barrier has various immunological and non‐immunological components. The epithelial barrier is one of the most important non‐immunological components. Hyperpermeability of this barrier is believed to contribute to the pathogenesis of several gastrointestinal disorders including inflammatory bowel disease, celiac disease and food allergy. Hence, assessing barrier integrity is of the utmost importance. One of the more quantitative gauges for this assessment is transepithelial permeability of various molecular probes, among which sugars are commonly used. Measures of intestinal permeability might also be useful as markers for assessment of prognosis and follow up in various gastrointestinal disorders. The present article is a review of the normal and abnormal functioning of the intestinal barrier, the diseases that can result from loss of barrier integrity, and some promising agents and strategies for restoring barrier normality and integrity. © 2003 Blackwell Publishing Asia Pty Ltd
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Cites
Reactive oxygen species in cell signaling
Thannickal, V. J., & Fanburg, B. L. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.6.l1005 · Cited by 2,927
Oxygen radicals and human disease
CROSS, C. E., HALLIWELL, B., BORISH, E. T., PRYOR, W. A., AMES, B. N., SAUL, R. L., McCORD, J. M., & HARMAN, D. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-4-526 · Cited by 1,856
Malaviya, R., Ikeda, T., Ross, E., & Abraham, S. N. (1996) · Nature · doi:10.1038/381077a0 · Cited by 1,123
Probiotics: A novel approach in the management of food allergy
Majamaa, H., & Isolauri, E. (1997) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(97)70093-9 · Cited by 918
HOLLANDER, D., VADHEIM, C. M., BRETTHOLZ, E., PETERSEN, G. M., DELAHUNTY, T., & ROTTER, J. I. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-6-883 · Cited by 760
Tibble, J. A., Sigthorsson, G., Bridger, S., Fagerhol, M. K., & Bjarnason, I. (2000) · Gastroenterology · doi:10.1053/gast.2000.8523 · Cited by 759
Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.
Madara, J. L., & Stafford, J. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113938 · Cited by 754
Xanthine oxidase and neutrophil infiltration in intestinal ischemia
Grisham, M. B., Hernandez, L. A., & Granger, D. N. (1986) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1986.251.4.g567 · Cited by 720
Epidemiology of Alcoholic Liver Disease
Grant, B., Dufour, M., & Harford, T. (1988) · Seminars in Liver Disease · doi:10.1055/s-2008-1040525 · Cited by 536
Deitch, E. A. (1990) · Archives of Surgery · doi:10.1001/archsurg.1990.01410150125024 · Cited by 482
Cited by
Kelly, J. R., Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G., & Hyland, N. P. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00392 · Cited by 1,110
Forsyth, C. B., Shannon, K. M., Kordower, J. H., Voigt, R. M., Shaikh, M., Jaglin, J. A., Estes, J. D., Dodiya, H. B., & Keshavarzian, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028032 · Cited by 974
Self-citationGut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration
Dinan, T. G., & Cryan, J. F. (2017) · The Journal of Physiology · doi:10.1113/jp273106 · Cited by 813
The Gut Microbiome, Kidney Disease, and Targeted Interventions
Ramezani, A., & Raj, D. S. (2014) · Journal of the American Society of Nephrology · doi:10.1681/asn.2013080905 · Cited by 743
Rera, M., Clark, R. I., & Walker, D. W. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215849110 · Cited by 613
Metadata
- Authors
- FARHADI, A., BANAN, A., FIELDS, J., & KESHAVARZIAN, A.
- Venue
- Journal of Gastroenterology and Hepatology
- Publisher
- Wiley
- Published
- 2003-04-15
- Volume
- 18
- Issue
- 5
- Pages
- 479-497
- ISSN
- 0815-9319 (ISSN-L)
- 1440-1746
- OpenAlex
- W1984172120
- Cited by
- 530
- References
- 158
- FWCI
- 11.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.