Brain Lactate Is an Obligatory Aerobic Energy Substrate for Functional Recovery After Hypoxia: Further In Vitro Validation

Neuronal Energy Requirements

Schurr, A. (2002) · Humana Press eBooks · doi:10.1007/978-1-59259-108-4_2 · Cited by 8

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Alessandri, B., Gugliotta, M., Levasseur, J. E., & Bullock, M. R. (2009) · Future Neurology · doi:10.2217/14796708.4.2.209 · Cited by 8

5.2 Nitric Oxide in Regulation of Mitochondrial Function, Respiration, and Glycolysis

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Lactate and Acute Heart Failure Syndrome

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Effect of the pyrrolopyrimidine lipid peroxidation inhibitor U-101033E on neuronal and astrocytic metabolism and infarct volume in rats with transient middle cerebral artery occlusion

Haberg, A. K., Qu, H., Hjelstuen, M., & Sonnewald, U. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2006.12.005 · Cited by 8

Neuromonitoring in Intensive Care

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Acetate enhances neuronal plasticity and reduces ischemic brain injury by promoting tau protein lactylation

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Monoclonal antibody 14F7, which recognizes a stage-specific immature oligodendrocyte surface molecule, inhibits oligodendrocyte differentiation mediated in co-culture with astrocytes

Yoshimura, K., Sakurai, Y., Nishimura, D., Tsuruo, Y., Nomura, M., Kawato, S., Seiwa, C., Iguchi, T., Itoh, K., & Asou, H. (1998) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19981001)54:1 · Cited by 15

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Brain slice viability determined under normoxic and oxidative stress conditions: involvement of slice quantity in the medium

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Utilization of Energy Nutrients by Cerebellar Slices

Rotta, L. N., Valle, S. C., Schweigert, I. D., Ricardi, L. M. D., Ferronatto, M. E. B., da Silva, L., Souza, D. O., & Perry, M. L. S. (2002) · Neurochemical Research · doi:10.1023/a:1014828419900 · Cited by 6

Dietary Carbamazepine Administration Decreases Liver Pyruvate Carboxylase Activity and Biotinylation by Decreasing Protein and mRNA Expression in Rats

Rathman, S. C., Blanchard, R. K., Badinga, L., Gregory, J. F., Eisenschenk, S. J., & McMahon, R. J. (2003) · Journal of Nutrition · doi:10.1093/jn/133.7.2119 · Cited by 6

pH regulation and acid/base-mediated transport in glial cells

Deitmer, J. W. (2004) · Springer eBooks · doi:10.1007/978-1-4020-7937-5_10 · Cited by 6

5.1 Acid–Base Transport and pH Regulation

Deitmer, J. W. (2007) · Springer eBooks · doi:10.1007/978-0-387-30411-3_17 · Cited by 5

Intraventricular lactate infusion attenuates the transactivational effects of the glucose antimetabolite, 2-deoxy-d-glucose, on hypothalamic vasopressinergic neurons

Briski, K. P. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01681-9 · Cited by 5

Corticosterone disrupts glucose-, but not lactate-supported hippocampal PS-LTP

Payne, R. S., & Schurr, A. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.07.006 · Cited by 5

Lactic Acidosis and Hyperlactatemia

Lévy, B. (2006) · Yearbook of intensive care and emergency medicine · doi:10.1007/3-540-33396-7_9 · Cited by 5

[31P]/[1H] Nuclear Magnetic Resonance Study of Mitigating Effects of GYKI 52466 on Kainate‐Induced Metabolic Impairment in Perfused Rat Cerebrocortical Slices

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Oxidation of 14C-labeled substrates by hippocampal slice cultures

Gilbert, E., & Bergold, P. J. (2005) · Brain Research Protocols · doi:10.1016/j.brainresprot.2005.06.002 · Cited by 5

Effect of hemic hypoxia on dynamics of GFAP concentrations in the structures of the brain and blood serum of rats

Duka, T., & Чорна, В. І. (2016) · Biosystems Diversity · doi:10.15421/011617 · Cited by 4

Pyruvate shuttle in muscle cells: high-affinity pyruvate transport sites insensitive totrans-lactate efflux

Mengual, R., ABIDA, K. E., Mouaffak, N., Rieu, M., & Beaudry, M. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00034.2003 · Cited by 3

Screening and identification of neuroprotective compounds produced by Lactobacillus paracasei subsp. paracasei NTU 101

Cheng, M., Leu, Y., Tsai, T., & Pan, T. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.07.021 · Cited by 3

Cerebral lactate metabolism and memory: Implications for Alzheimer's disease

Harris, R. A. (2017) · Scholarship@Western (Western University) · Cited by 3

Lactate flux dysfunction in patients with bipolar disorder: preliminary insights from ultra-high field 7T MRSI during task and rest

Bertocci, M. A., & Diler, R. S. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1587011 · Cited by 2

Lactate alleviates trigeminal neuralgia symptoms in mice by suppressing neuroinflammation

Liu, X., Long, F., Zou, W., & Qi, T. (2025) · Journal of International Medical Research · doi:10.1177/03000605251341802 · Cited by 2

Glucose and Lactate Utilization by the Amygdala of Male and Female Rats

Rasia‐Filho, A. A., Fin, C. A., Alves, M. D., Possa, M. D. A., Roehrig, C., Feóli, A. M. P., Silva, L., & Perry, M. L. S. (2002) · Neurochemical Research · doi:10.1023/a:1021666406738 · Cited by 2

Glutamate and Glutamine in Brain Disorders

Bak, L. K., Schousboe, A., & Waagepetersen, H. S. (2010) · Advances in neurobiology · doi:10.1007/978-1-4419-7104-3_7 · Cited by 2

Hyperglycemia and neuronal damage in cerebral ischemia and beyond

Schurr, A., & Payne, R. S. (2003) · Cited by 2

Lactate: métabolisme et physiopathologie

Orban, J., Ichaï, C., & Leverve, X. M. (2011) · Springer eBooks · doi:10.1007/978-2-287-99027-4_8 · Cited by 2

Lactate: Metabolism, Pathophysiology

Ichaï, C., & Orban, J. (2017) · Springer eBooks · doi:10.1007/978-3-319-64010-5_8 · Cited by 2

Lactic Acidosis and Hyperlactatemia

Lévy, B. (2007) · Springer eBooks · doi:10.1007/0-387-35096-9_9 · Cited by 2

Secondary Insults in Neurointensive Care of Patients with Traumatic Brain Injury

Elf, K. (2005) · KTH Publication Database DiVA (KTH Royal Institute of Technology) · Cited by 2

Effects of lactate-based therapies on intracranial pressure and brain metabolism of patients with acute brain injury: a systematic review

García, N. R., Zarco, A. R., Ruiz-Pacheco, A., Mata, S. Ú., Milian, J. M., Monleón, B., Marín, N. S., Oddo, M., Bouzat, P., Resch, P., et al. (2026) · Critical Care · doi:10.1186/s13054-026-05973-3 · Cited by 1

Chapter 5.4 Online glucose and lactate monitoring during physiological and pathological conditions

Fillenz, M. (2006) · Handbook of behavioral neuroscience · doi:10.1016/s1569-7339(06)16024-5 · Cited by 1

Monitoring of Acute Traumatic Brain Injury In Adults To Prevent Secondary Brain Damage

Bothe, M. K., & Stover, J. F. (2014) · Future Neurology · doi:10.2217/fnl.13.78 · Cited by 1

Retinal glucose metabolism in mice lacking the L-glutamate/aspartate transporter

Sarthy, V. P., Dudley, V. J., & Tanaka, K. (2004) · Visual Neuroscience · doi:10.1017/s0952523804214122 · Cited by 1

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Roberts, E. L., & Chih, C.-P. (2003) · Advances in molecular and cell biology · doi:10.1016/s1569-2558(03)31017-3 · Cited by 1

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Quintard, H., & Ichaï, C. (2014) · Annales Françaises d Anesthésie et de Réanimation · doi:10.1016/j.annfar.2014.05.007 · Cited by 1

Lactate is the ultimate oxidative energy substrate in brain and elsewhere

Schurr, A. (2005) · Cited by 1

Monitoring Tissue Perfusion: Clinicopathologic Aids and Advanced Techniques

Young, B. C. (2012) · doi:10.1002/9781118997246.ch15 · Cited by 1

The role of hypoxia in neuroinflammatory disease

Desai, R. (2013) · UCL Discovery (University College London) · Cited by 1

Non-invasive near infrared spectroscopy : a tool for measuring cerebral oxygenation and metabolism in patients with traumatic brain injury

Tisdall, M. M. (2007) · UCL Discovery (University College London) · Cited by 1

Hippocampal Slices and Their Electrophysiogy in the Study of Brain Energy Metabolism

Schurr, A. (2012) · InTech eBooks · doi:10.5772/27992

REDOX PROTEOMICS IDENTIFICATION OF OXIDATIVELY MODIFIED PROTEINS AND THEIR PHARMACOLOGICAL MODULATION: INSIGHT INTO OXIDATIVE STRESS IN BRAIN AGING, AGE-RELATED COGNITIVE IMPAIRMENT

Poon, H. F. (2005) · UKnowledge (University of Kentucky)

EFFECTS OF ORAL CARBAMAZEPINE ADMINISTRATION ON BIOTIN METABOLISM IN RATS

Rathman, S. C. (2003)

New Insights into the Acetaminophen Hepatotoxicity Research

Yang, R. (2014) · Journal of Anesthesia & Critical Care Open Access · doi:10.15406/jaccoa.2014.01.00004

Monitorage du choc cardiogénique

Ducrocq, N., Kimmoun, A., & Lévy, B. (2011) · Réanimation · doi:10.1007/s13546-011-0424-y

High-Dose Albumin for Neuroprotection in Acute Ischemic Stroke: From Basic Investigations to Multicenter Clinical Trial

Ginsberg, M. D. (2012) · Springer eBooks · doi:10.1007/978-1-4419-9530-8_34

UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL INSTITUTO DE CIÊNCIAS BÁSICAS DA SAÚDE PPG CIÊNCIAS EM BIOLÓGICAS: BIOQUÍMICA ENVOLVIMENTO DO SISTEMA PURINÉRGICO, LACTATO E GLICOSE EM INSULTOS DO SISTEMA NERVOSO CENTRAL

Oses, J. P. (2008)

Commentary Lactate: a key metabolite in the intercellular metabolic interplay

Leverve, X. M., & Mustafa, I. (2002)

Les méthodes disponibles d’appréciation au lit du malade des circulations régionales et du fonctionnement cellulaire

Vallet, B., & Lévy, B. (2007) · Springer eBooks · doi:10.1007/978-2-287-71154-1_9

Cardiogenic shock monitoring

Ducrocq, N., Kimmoun, A., & Lévy, B. (2012)

Albumin in Acute Stroke (ALIAS) Trial-Part 2: A Phase III Randomized Multicenter Clinical Trial of High-Dose Human Albumin Therapy for Neuroprotection in Acute Ischemic Stroke

Ginsberg, M. D., Scheinberg, P., & Hill, M. D. (2010)

THE ROLE OF MEMBRANE TRANSPORTERS IN TRAUMATIC BRAIN INJURY: INTERVENTIONAL AND GENETIC INVESTIGATIONS

Hagos, F. T. (2018) · D-Scholarship@Pitt (University of Pittsburgh)

Hyperlactatémie en réanimation

Ichaï, C. (2020) · Anesthésie & Réanimation · doi:10.1016/j.anrea.2020.11.005

The Central Role of Astrocytes in Neuroenergetics

Magistretti, P. J., & Pellerin, L. (2012) · doi:10.1093/med/9780199794591.003.0027

Lactate

Lévy, B. (2009) · Elsevier eBooks · doi:10.1016/b978-2-8101-0089-7.50018-4

Neuroprotective role of lactate in a human in vitro model of the ischemic penumbraPreprint

Cerina, M., Levers, M., Keller, J. M., & Frega, M. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.28.550936

Research Progress on the Correlation between Blood Lactic Acid and Acute Heart Failure

丁, 慧. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.1392012

Les neurones pyramidaux corticaux dans le couplage neurovasculaire et neurométabolique : mécanismes cellulaires et moléculaires

Lacroix, A. (2014) · theses.fr (ABES) · doi:10.70675/2e744402z02b6z4b77z8559z29ba7bc32510

Brain lactate, not glucose, fuels the recovery of synaptic function from hypoxia upon reoxygenation: an in vitro study

Schurr, A., Payne, R. S., Miller, J. J., & Rigor, B. M. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01106-7 · Cited by 262

Glia are the main source of lactate utilized by neurons for recovery of function posthypoxia

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Direct Evidence that Lactate is an Obligatory Aerobic Energy Substrate for Functional Recovery Posthypoxia in Vitro

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Electrophysiology of energy metabolism and neuronal function in the hippocampal slice preparation

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Lactate-supported synaptic function in the rat hippocampal slice preparation.

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