Cited by 174Mast cells and histamineSystemic Sclerosis and Related DiseasesWound Healing and Treatments

The DOI matches its Crossref record; 68 of the 70 references it cites were found in a registry or an index.

The Differentiation and Function of Myofibroblasts is Regulated by Mast Cell Mediators

Open access

Gailit, James, Marchese, Mary J., Kew, Richard R., Gruber, Barry L.·2001·Journal of Investigative Dermatology

DOI 10.1046/j.1523-1747.2001.15211.x

Open this paper in CoChat — free account Open PDF

Abstract

Myofibroblasts are fibroblasts that express certain features of smooth muscle differentiation. Increased numbers of myofibroblasts and mast cells are frequently found together in a wide variety of settings, such as normal wound repair and scleroderma skin, which suggests that mediators produced by the mast cells could play a role in the regulation of myofibroblast differentiation and function. We used a human mast cell line, HMC-1, to determine if mast cells can induce normal human dermal fibroblasts to differentiate into functional myofibroblasts in vitro. We monitored the differentiation process by assaying two properties of the myofibroblast phenotype: expression of alpha-smooth muscle actin and functional capacity to contract a collagen matrix. In both a simple coculture system and in a skin-equivalent culture system, HMC-1 cells induced alpha-smooth muscle actin expression by fibroblasts. HMC-1 cells also stimulated fibroblast contraction of collagen gels, and the relative amount of contraction was dependent upon the number of HMC-1 cells present. To characterize the individual contributions made by specific mast cell products, we examined the effects of histamine, tumor necrosis factor alpha, and tryptase. Histamine induced a clear increase in alpha-smooth muscle actin expression, but it did not appear to stimulate fibroblast contraction. Tumor necrosis factor alpha had no effect in either assay. Purified human tryptase induced alpha-smooth muscle actin expression, and blocking the proteolytic activity of tryptase with specific inhibitors reduced that response. Tryptase inhibitors also eliminated the ability of HMC-1 cells to stimulate fibroblast contraction, suggesting that tryptase secreted by the HMC-1 cells may be one of the active mast cell mediators.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1046/j.1523-1747.2001.15211.x

Cites

68 of 68 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
Desmoulière, A., Geinoz, A., Gabbiani, F., & Gabbiani, G. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.122.1.103 · Cited by 2,269
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
Friedman, S. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.4.2247 · Cited by 2,067
Mast cells
Metcalfe, D. D., Baram, D., & Mekori, Y. A. (1997) · Physiological Reviews · doi:10.1152/physrev.1997.77.4.1033 · Cited by 1,723
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
Gabbiani, G., Ryan, G. B., & Majno, G. (1971) · Experientia · doi:10.1007/bf02147594 · Cited by 1,485
Fibroblasts, myofibroblasts, and wound contraction
Grinnell, F. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.124.4.401 · Cited by 1,141
Identification, culture, and characterization of pancreatic stellate cells in rats and humans
Bachem, M. G., Schneider, E., Groß, H., Weidenbach, H., Schmid, R. M., Menke, A., Siech, M., Beger, H. G., Grünert, A., & Adler, G. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70209-4 · Cited by 1,017
Myofibroblasts. I. Paracrine cells important in health and disease
Powell, D. W., Mifflin, R. C., Valentich, J. D., Crowe, S. E., Saada, J. I., & West, A. B. (1999) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1999.277.1.c1 · Cited by 974
Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations.
Sappino, A. P., Schürch, W., & Gabbiani, G. (1990) · PubMed · Cited by 833
Proteinase-activated receptors: novel mechanisms of signaling by serine proteases
Déry, O., Corvera, C. U., Steinhoff, M. S., & Bunnett, N. W. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.274.6.c1429 · Cited by 775
Establishment of an immature mast cell line from a patient with mast cell leukemia
Butterfield, J. H., Weiler, D., Dewald, G., & Gleich, G. J. (1988) · Leukemia Research · doi:10.1016/0145-2126(88)90050-1 · Cited by 737

Show all 70 references

Research works printed but not linked: 1

Ronnov-Jessen, 1993, Induction of α-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts, Lab Invest, 68, 696

Sorted by citations

Items 101–173 of 173

Myofibroblasts and mast cells: influences on biological behavior of odontogenic lesions
Pereira, J. D. S., de Nóbrega, F. J., VASCONCELOS, R. G., Câmara, A. C. D. S. M., de Souza, L. B., & Queiroz, L. M. G. (2016) · Annals of Diagnostic Pathology · doi:10.1016/j.anndiagpath.2014.09.003 · Cited by 16
Effect of Keratinocytes on Myofibroblasts in Hypertrophic Scars
Lee, J. S., Kim, J. S., Lee, J. W., Choi, K. Y., Yang, J. D., Cho, B. C., Oh, E. J., Kim, T. J., Ko, U. H., Shin, J. H., et al. (2019) · Aesthetic Plastic Surgery · doi:10.1007/s00266-019-01434-1 · Cited by 15
Properties and Immune Function of Cardiac Fibroblasts
Furtado, M. B., & Hasham, M. G. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-57613-8_3 · Cited by 15
Do mast cells affect villous architecture? Facts and conjectures.
Crivellato, E., Finato, N., Ribatti, D., & Beltrami, C. A. (2005) · PubMed · doi:10.14670/hh-20.1285 · Cited by 15
Exploring the role of granzyme B in subretinal fibrosis of age-related macular degeneration
Gill, K., Yoo, H.-S., Chakravarthy, H., Granville, D. J., & Matsubara, J. A. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1421175 · Cited by 14
Clinicopathological characteristics of odontogenic myxoma in Nigerians.
Effiom, O. A., Adewole, R. A., & Odukoya, O. O. (2011) · PubMed · Cited by 14
Number of pericryptal fibroblasts correlates with density of distinct mast cell phenotypes in the crypt lamina propria of human duodenum: Implications for the homeostasis of villous architecture
Crivellato, E., Finato, N., Isola, M., Pandolfi, M., Ribatti, D., & Beltrami, C. A. (2006) · The Anatomical Record Part A Discoveries in Molecular Cellular and Evolutionary Biology · doi:10.1002/ar.a.20325 · Cited by 14
Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts
Antebi, B., Zhang, L., Sheyn, D., Pelled, G., Zhang, X., Gazit, Z., Schwarz, E. M., & Gazit, D. (2016) · Bioengineering · doi:10.3390/bioengineering3010006 · Cited by 13
Immunocytochemical characterisation of cultures of human bladder mucosal cells
Woodman, J. R., Mansfield, K. J., LAZZARO, V. A., Lynch, W., Burcher, E., & Moore, K. H. (2011) · BMC Urology · doi:10.1186/1471-2490-11-5 · Cited by 13
Implication de l'interleukine 13 et de son récepteur dans la sclérodermie systémique
Granel, B., Chevillard, C., & Dessein, A. J. J. (2007) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2007.04.005 · Cited by 14
Dextranomer/Hyaluronic Acid Copolymer Implant for Vesicoureteral Reflux: Role of Myofibroblast Differentiation
Arena, S., Fazzari, C., Implatini, A., Torre, S., Villari, D., Arena, F., & Benedetto, V. D. (2009) · The Journal of Urology · doi:10.1016/j.juro.2009.02.059 · Cited by 12
Simultaneous blockade of alpha and beta adrenoceptors impairs cutaneous wound healing in rats
Romana‐Souza, B., & Monte‐Alto‐Costa, A. (2009) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2009.03376.x · Cited by 11
Mast cell infiltration associated with tubulointerstitial fibrosis in chronic Aristolochic Acid Nephropathy
Wu, Y., Liu, Z., Hu, W., & Leishi, L. (2005) · Human & Experimental Toxicology · doi:10.1191/0960327105ht502oa · Cited by 10
Ccn2/Ctgf Overexpression Induced by Cigarette Smoke during Cutaneous Wound Healing is Strain Dependent
Cardoso, J. F., Mendes, F. A., Amadeu, T. P., Romana‐Souza, B., Valença, S. S., Pôrto, L. C., Abreu, J. G., & Monte‐Alto‐Costa, A. (2009) · Toxicologic Pathology · doi:10.1177/0192623308328134 · Cited by 10
Harnessing the Power of Mast Cells in unconventional Immunotherapy Strategies and Vaccine Adjuvants
Willows, S. D., & Kulka, M. (2020) · Cells · doi:10.3390/cells9122713 · Cited by 10
The potential role of mast cells and fibroblast growth factor-2 in the development of hypertension-induced renal damage
Stanchev, S., Landzhov, B. V., Kotov, G. N., Stamenov, N., Dikov, T. I., & Iliev, A. A. (2020) · Acta Histochemica · doi:10.1016/j.acthis.2020.151599 · Cited by 9
ENHANCEMENT OF LIPID BODIES DURING DIFFERENTIATION OF SKELETAL MYOFIBROBLASTS OF RAT'S FETUS IN VITRO
Pereira, R. O., de Carvalho, T. M. U., Barbosa, H. S., Pôrto, L. C., & de Carvalho, L. (2004) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1290/0401003 · Cited by 9
Examining the Role of Mast Cells in Fetal Wound Healing Using Cultured Cells In Vitro
Wulff, B. C., & Wilgus, T. A. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-505-7_29 · Cited by 8
An assessment of mast cells and myofibroblasts in denture‐induced fibrous hyperplasia
Kiuchi, M., Yamamura, T., Okudera, M., Vongsa, S., Ishigami, T., Iwase, T., Warnakulasuriya, S., & Komiyama, K. (2013) · Journal of Oral Pathology and Medicine · doi:10.1111/jop.12072 · Cited by 8
Gene expression profiling of inflammatory bladder disorders
Saban, M. R., Nguyen, N. B., & Hurst, R. E. (2003) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.3.2.217 · Cited by 8
Mast cells and ocular surface: An update review
Barone, V., Scirocco, L., Surico, P. L., Micera, A., Cutrupi, F., Coassin, M., & Zazzo, A. D. (2024) · Experimental Eye Research · doi:10.1016/j.exer.2024.109982 · Cited by 8
Mast cells and wound healing: Still an open question.
Fernández-Guarino, M., & Bacci, S. (2025) · PubMed · doi:10.14670/hh-18-757 · Cited by 7
Development of immunocompetent full thickness skin tissue constructs to model skin fibrosis for high-throughput drug screening
Lim, Y. W., Quinn, R., Bharti, K., Ferrer, M., Zarkoob, H., & Song, M. J. (2024) · Biofabrication · doi:10.1088/1758-5090/ad998c · Cited by 7
Granzyme B contributes to subretinal fibrosis in neovascular age-related macular degeneration by modulating inflammation and epithelial-mesenchymal transition
Yoo, H.-S., Chakravarthy, H., Xi, J., Cui, J. Z., Ai, Z., Hosseini, A., Song, J. L., Tan, N., Ma, N., Zhou, C., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03619-9 · Cited by 6
Integration of the Human Dermal Mast Cell into the Organotypic Co-culture Skin Model
Kim, J., Guhl, S., Babina, M., Zuberbier, T., & Artuc, M. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0696-4_8 · Cited by 6
Role of cytokines in lavage or drainage fluid after hemithyroidectomy in wound healing: Involvement of histamine in the acceleration and delay of wound healing
Arai, M., Ogita‐Nakanishi, H., Lee, K., Yoshimura, K., Kawata, R., Kanazawa, A., Terada, T., Takenaka, H., Sato, T., Endo, Y., et al. (2012) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2012.00770.x · Cited by 6
Involvement of mast cells and microvessels density in reactive lesions of oral cavity: A comparative immunohistochemical study
Ferreira, S. V., Xavier, F. C. D. A., de Freitas, M. D. C. A., Nunes, F. D., Gurgel, C. A. S., Cangussú, M. C. T., Martins, M. D., Freitas, V. S., & dos Santos, J. N. (2016) · Pathology - Research and Practice · doi:10.1016/j.prp.2016.05.007 · Cited by 6
EGF-expressed human mesenchymal stem cells inhibit collagenase1 expression in keratinocytes
Lee, J. H., Chellasamy, G., Yun, K., & Nam, M. J. (2023) · Cellular Signalling · doi:10.1016/j.cellsig.2023.110827 · Cited by 5
Neuropeptides, Inflammation, and Diabetic Wound Healing: Lessons from Experimental Models and Human Subjects
Tellechea, A., Pradhan‐Nabzdyk, L., LoGerfo, F. W., & Veves, A. (2018) · Contemporary diabetes · doi:10.1007/978-3-319-89869-8_8 · Cited by 6
Integration of the Human Dermal Mast Cell into the Organotypic Co-culture Skin Model
Kim, J., Guhl, S., Babina, M., Zuberbier, T., & Artuc, M. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1173-8_6 · Cited by 5
Physiologie de la cicatrisation cutanée
Pillouer-Prost, A. L., & Coulomb, B. (2009) · EMC - Cosmétologie et dermatologie esthétique · doi:10.1016/s1283-0143(09)70746-0 · Cited by 5
Effects of Oligoelements Se, Zn, and Mn plus Lachesis Muta Venom in Experimental Scleroderma
Crescenti, E. J., Medina, V. A., Sambuco, L. A., Cremaschi, G., Genaro, A. M., Cricco, G., Martín, G., Valli, E., Lamas, D. J. M., Perazzo, J. C., et al. (2013) · Biological Trace Element Research · doi:10.1007/s12011-013-9876-4 · Cited by 5
A relationship between mast cells and α-smooth muscle actin-positive cells in the nasal polyps of chronic rhinosinusitis
Nishijima, I., Sanai, A., & Yoshihara, T. (2009) · Acta Oto-Laryngologica · doi:10.1080/00016480902936919 · Cited by 5
Alteration in myocardial prostaglandin D synthase expression in pressure overload-induced left ventricular remodeling in rats
Nagalla, K. T., Gole, M., Claudino, M. A., Gardner, J. D., & Murray, D. B. (2012) · Experimental Biology and Medicine · doi:10.1258/ebm.2011.011180 · Cited by 5
Cell-Type-Specific Differentiation and Molecular Profiles in Skin Transplantation: Implication of Medical Approach for Genetic Skin Diseases
Oyama, N., & Kaneko, F. (2011) · Journal of Transplantation · doi:10.1155/2011/501857 · Cited by 4
Expression and modulation of S100A4 protein by human mast cells
Domenis, R., Pilutti, D., Orsaria, M., Marzinotto, S., Candotti, V., Bosisio, G., Bulfoni, M., Ruaro, M. E., Loreto, C. D., Mea, V. D., et al. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.08.001 · Cited by 4
Histopathological, Ultrastructural, and Immunohistochemical Findings in Radial Longitudinal Deficiency: A Prospective, Observational Study
Mittal, S., Garg, B., Mehta, N. H., Kumar, V., Karpe, A., Kakkar, A., Sharma, M. C., Sarkar, C., & Kotwal, P. P. (2021) · The Journal Of Hand Surgery · doi:10.1016/j.jhsa.2021.07.004 · Cited by 4
Mast cell tryptase‐PAR2 pathway in proliferation of prostatic stromal cells reacted with Trichomonas vaginalis
Noh, C. H., Chung, H., Han, I., Kim, J., Kim, Y., & Ryu, J. (2021) · Parasite Immunology · doi:10.1111/pim.12868 · Cited by 4
Role of mast cells in cow metritis
Wang, G., Hou, J.-L., Huang, H.-Y., & Yuan, C. (2016) · Journal of Veterinary Research · doi:10.1515/jvetres-2016-0026 · Cited by 4
Fisetin promotes skin wound healing and inhibits pathological scar formation through modulation of the PI3K/Akt/TGF-β1 signaling axis
Han, Y., & Sun, G. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1793847 · Cited by 3
Human airway trypsin‐like protease (HAT) is released into saliva
Yasuoka, S., Miki, M., Tsutsumi, R., Yoshioka, M., Bando, T., & Michishige, F. (2018) · The Journal of Medical Investigation · doi:10.2152/jmi.65.258 · Cited by 3
Testosterone and Mast Cell Interactions in the Development of Kidney Fibrosis after Unilateral Ureteral Obstruction in Rats
de Oliveira-Silva, G. L., Morais, I. B. D. M., Silva, J. F., Alvarez, M. M. P., França-Silva, N., Galo, J. A., Hiraki, K. R. N., Balbi, A. P. C., & Bispo-da-Silva, L. B. (2018) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b17-00829 · Cited by 3
Mast Cell Modulation of the Tumor Microenvironment
Oldford, S. A., & Marshall, J. S. (2013) · Springer eBooks · doi:10.1007/978-94-007-6217-6_20 · Cited by 3
Effects of Disodium Cromoglycate Treatment in the Early Stage of Diabetic Nephropathy: Focus on Collagen Deposition
Luz, M., da Costa, V. A. A., Balbi, A. P. C., & Bispo-da-Silva, L. B. (2022) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b21-00662 · Cited by 2
Cromolyn sodium and masitinib combination inhibits fibroblast‐myofibroblast transition and exerts additive cell‐protective and antioxidant effects on a bleomycin‐induced in vitro fibrosis model
Erol, A. Y. G., Dirol, H., & Koçancı, F. G. (2024) · Pharmacology Research & Perspectives · doi:10.1002/prp2.70018 · Cited by 2
Hypertrophic scar in a dog: histological and clinical features
Avallone, G., Bonaldi, M., Caniatti, M., & Lombardo, R. (2011) · Veterinary Dermatology · doi:10.1111/j.1365-3164.2011.00960.x · Cited by 2
Role of Lysosomal Cathepsins in Post-Myocardial Infarction Remodeling
Chen, H., Wang, J., & Shi, G. (2011) · North American Journal of Medicine and Science · doi:10.7156/v4i4p173 · Cited by 2
Signs of Cell-Cell Interactions in Sarcoma 45 Tissue Under Conditions of Antitumor Effect Caused by Injection of Magnetite Nanoparticles
Gudtskova, T. N., Zhukova, G. V., Bragina, M. I., Гаркави, Л. Х., Mikholap, A. I., & Barteneva, T. A. (2013) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-013-2254-6 · Cited by 2
Tissue Remodeling and Repair During Type 2 Inflammation
Chan, A. J., Jang, J. C., & Nair, M. G. (2015) · Springer eBooks · doi:10.1007/978-1-4939-2911-5_7 · Cited by 3
Histological study of human abdominal skin after repeated pregnancy
Ghafeer, H. H., Elgamal, D. A., Mostafa, N., & Hassanin, A. I. (2015) · The Egyptian Journal of Histology · doi:10.1097/01.ehx.0000460028.14258.f2 · Cited by 2
The Role of Myofibroblasts and Mast Cells in Oral Mucosa Repair After Fractional Laser Treatment
Sergeeva, E. S., Гусельникова, В. В., Ermolaeva, L. A., Belikov, A. V., Fedotov, D. Y., Суфиева, Д. А., Semyashkina, Y. V., Antropova, M. M., & Korzhevsky, D. E. (2019) · Journal of Anatomy and Histopathology · doi:10.18499/2225-7357-2019-8-1-59-67 · Cited by 2
Fibroblasts as matrix modulating cells in asthma and COPD
Nihlberg, K. (2009) · Lund University Publications (Lund University) · Cited by 2
Regulation of Skin Wound Healing by Zinc and Zinc Transporters
Nishida, K., & Nakagawa, N. (2025) · Royal Society of Chemistry eBooks · doi:10.1039/9781837676583-00202 · Cited by 1
Dynamic Action of Myofibroblasts in Skin and Bone Marrow Transplantation
Oyama, N. (2014) · Journal of Bone Marrow Research · doi:10.4172/2329-8820.1000143 · Cited by 1
Reactive Oxygen Species and Scleroderma
Yamamoto, T. (2014) · Springer eBooks · doi:10.1007/978-3-642-30018-9_105 · Cited by 1
Estimates of Risk, Empirical Treatment Observations, and Unexpected Laboratory Findings Reveal the Complexity of Nephrogenic Systemic Fibrosis
High, W. A. (2009) · Archives of Dermatology · doi:10.1001/archdermatol.2009.227 · Cited by 1
Mast cell mediated myofibroblast differentiation responsible for progression of oral submucous fibrosis
Reddy, M. G. S., Kakodkar, P. V., & Mehta, V. (2024) · Oral Oncology Reports · doi:10.1016/j.oor.2024.100216 · Cited by 1
Mast Cells in Experimental Myocardial Infarction
Frangogiannis, N. G., & Entman, M. L. (2003) · Developments in cardiovascular medicine · doi:10.1007/978-1-4419-9264-2_11
Fisiologia della cicatrizzazione cutanea
Pillouer-Prost, A. L., & Coulomb, B. (2009) · EMC - Cosmetologia Medica e Medicina degli Inestetismi Cutanei · doi:10.1016/s1776-0313(09)70244-8
Clinical characteristics of the H1N1 virus
Abbas, S. A. (2009) · Thorax · doi:10.1136/thx.2009.127399
Updates on the pathophysiology of dermal sclerosis
Yamamoto, T. (2012) · Expert Review of Dermatology · doi:10.1586/edm.12.57
Participação de Smad7 e CTGF na transdiferenciação de miofibroblastos gengivais e análise da influência dos miofibroblastos na proliferação e invasão de carcinomas espinocelulares orais
Sobral, L. M. (2010) · doi:10.47749/t/unicamp.2010.778750
The role of mast cells in the immune response against bacterial infections
Zimmermann, C. (2016) · DepositOnce · doi:10.14279/depositonce-5528
Role of Intercellular Interactions between Mast Cells and Gingival Fibroblasts in Mediating Inflammation
Termei, R. (2011) · TSpace (University of Toronto)
The Role of Mast Cells in the Pathophysiology of Pulmonary Fibrosis
Shimbori, C., Upagupta, C., Forsythe, P., & Kolb, M. R. J. (2018) · Molecular and translational medicine · doi:10.1007/978-3-319-98143-7_6
Interação entre testosterona e atividade mastocitária no desenvolvimento da fibrose renal induzida por obstrução ureteral em ratos wistar
Silva, G. (2015) · doi:10.14393/ufu.di.2015.166
Human epidermal growth factor-expressing mesenchymal stem cells reduce matrix metalloproteinase-1 expression via the mitogen-activated protein kinase pathway in human keratinocyte HaCaT cellsPreprint
Lee, J. H., Lee, C. M., Choi, Y. J., Park, S., & Nam, M. J. (2021) · Research Square · doi:10.21203/rs.3.rs-716671/v1
Cellular interactions of airway smooth muscle and human lung mast cells
Woodman, L. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)
Effect of normal saline in different concentration on soft tissue healing of extraction wound: a clinical study
Kunthikarn, W. (2022) · doi:10.58837/chula.the.2022.269
Immature mast cells predominate in skin wound repair in senescent mice
Coelho, M. M., Barreto, R. D. M., de Resende, J. A. P., Monteiro, J. F., Costa, R. A. D. C., Pinto, F. C. H., Carvalho, C. R., & Cost, R. A. (2023) · Indian Journal of Experimental Biology · doi:10.56042/ijeb.v61i12.6514
Neuropeptides, Inflammation, and Diabetic Wound Healing: Lessons from Experimental Models and Human Subjects
Mota, L., LoGerfo, F. W., Veves, A., & Pradhan‐Nabzdyk, L. (2024) · Contemporary diabetes · doi:10.1007/978-3-031-55715-6_9
The Ischemic Switch: From Raynaud’s Phenomenon to Autoallergic Mast Cell-Driven Vasculopathy in Systemic Sclerosis
Artlett, C. M. (2026) · Sclerosis · doi:10.3390/sclerosis4030020
Miofibroblastos são frequentes no estroma e no fronte invasivo dos carcinomas espinocelulares orais onde controlam o comportamento tumoral por estimular a proliferação celular e a atividade da metaloproteinase de matriz 2 das células tumorais
Kellermann, M. G. (2007) · doi:10.47749/t/unicamp.2007.395228

Authors: Gailit, J., Marchese, M. J., Kew, R. R., & Gruber, B. L.
Affiliations: Northport VA Medical Center (US)
State University of New York (US)
Corresponding author: Gruber, Barry L.
ORCID: Kew, Richard R.
Gruber, Barry L.
Venue: Journal of Investigative Dermatology
Publisher: Elsevier BV
Published: 2001-11
Volume: 117
Issue: 5
Pages: 1113-1119
ISSN: 0022-202X (ISSN-L)
DOI: 10.1046/j.1523-1747.2001.15211.x
OpenAlex: W2082391434
Cited by: 174
References: 70
Citations by year: 2026: 2 · 2025: 4 · 2024: 8 · 2023: 3 · 2022: 5 · 2021: 4 · 2020: 9 · 2019: 5 · 2018: 11 · 2017: 2 · 2016: 7 · 2015: 6 · 2014: 11 · 2013: 20 · 2012: 8
FWCI: 1.62
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5144 d)
Locations: Journal of Investigative Dermatology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Mast cells and histamine
Health Sciences › Medicine › Rheumatology › Systemic Sclerosis and Related Diseases
Health Sciences › Medicine › Surgery › Wound Healing and Treatments
Keywords: myofibroblasts, mast cells, mast cell mediators, fibroblast differentiation, alpha-smooth muscle actin, collagen gel contraction, tryptase, histamine, TNF-α, HMC-1 cells, dermal fibroblasts, systemic sclerosis, wound healing
MeSH terms: Actins, Cell Differentiation, Cell Line, Collagen, Fibroblasts, Histamine, Humans, Mast Cells, Muscle, Smooth, Organ Culture Techniques, Serine Endopeptidases, Tumor Necrosis Factor-alpha, Tryptases

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Differentiation and Function of Myofibroblasts is Regulated by Mast Cell Mediators

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks