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Cited by 41Dermatologic Treatments and ResearchSkin Protection and Agingmelanin and skin pigmentation

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Efficacy of Hydroquinone Cream (USP 4%) Used Alone or in Combination with Salicylic Acid Peels in Improving Photodamage on the Neck and Upper Chest

Gladstone, Hayes B., Nguyen, Serene L., Williams, Ronda, Ottomeyer, Tamy, Wortzman, Mitchell, Jeffers, Monica, Moy, Ronald L.·2000·Dermatologic Surgery
DOI 10.1046/j.1524-4725.2000.99233.x
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Abstract

BACKGROUND: Salicylic acid, hydroquinone, and glycolic acid have been proved effective in the treatment of photodamaged facial skin. Few reports are available on the treatment of photodamage on the neck and upper chest. OBJECTIVE: This study's purpose was to evaluate the efficacy of a cream containing 4% hydroquinone and 2% glycolic acid (LUSTRA) used alone or with salicylic acid peels in reversing actinic damage on the neck and upper chest. METHODS: Nineteen women with moderate to advanced photodamage on the neck and upper chest applied a cream containing 4% hydroquinone and 2% glycolic acid twice daily on photodamaged areas for 12 weeks. Nine of these subjects had salicylic acid peels every 3 weeks. Improvements were assessed by the investigator, the subjects, and Mexameter readings measuring melanin and erythema levels. RESULTS: The result shows that there was a 33-71% improvement in photodamage, hyperpigmentation, texture, fine lines, dryness, tone, and clarity in both groups. There were no significant differences between the two treatments. CONCLUSION: Hydroquinone 4% cream with 2% glycolic acid is safe and effective in improving photodamage on the neck and upper chest when used alone or in combination with salicylic acid peels.

Overview

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Crossref · 10.1046/j.1524-4725.2000.99233.x

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13 of 13 references verified0 citation errors · 0 not checkable

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Show all 13 references

Research works printed but not linked: 6

  1. 10.1016/S1076-0512(97)00508-6 · doi:10.1016/s1076-0512(97)00508-6
  2. 10.1016/S1076-0512(97)00179-9 · DOI
  3. 10.1016/1076-0512(96)00065-9 · doi:10.1016/1076-0512(96)00065-9
  4. 10.1016/1076-0512(96)00064-7 · doi:10.1016/1076-0512(96)00064-7
  5. 10.1016/S1076-0512(98)00024-7 · doi:10.1016/s1076-0512(98)00024-7
  6. 10.1016/S1076-0512(98)00060-0 · doi:10.1016/s1076-0512(98)00060-0

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Metadata

Authors
Gladstone, H. B., Nguyen, S. L., Williams, R., Ottomeyer, T., Wortzman, M., Jeffers, M., & Moy, R. L.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Moy, Ronald L.
ORCID
Wortzman, Mitchell
Venue
Dermatologic Surgery
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2000-04
Volume
26
Issue
4
Pages
333-337
ISSN
1076-0512 (ISSN-L)
DOI
10.1046/j.1524-4725.2000.99233.x
OpenAlex
W1995429164
Cited by
41
References
13
Citations by year
2025: 1 · 2024: 3 · 2023: 1 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 3
FWCI
2.79
Type
journal article
Language
en
Open access
closed
Locations
  • Dermatologic Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
Keywords
hydroquinone, glycolic acid, photodamage, actinic damage, neck skin, hyperpigmentation, skin texture, Mexameter, melanin, erythema
MeSH terms
Chemexfoliation, Female, Glycolates, Humans, Hydroquinones, Keratolytic Agents, Neck, Ointments, Thorax, Monophenol Monooxygenase, Skin Aging, Hyperpigmentation, Salicylic Acid

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CoChat. (2026). Citation check: Efficacy of Hydroquinone Cream (USP 4%) Used Alone or in Combination with Salicylic Acid Peels in Improving Photodamage on the Neck and Upper Chest. https://app.cochat.ai/papers/10.1046/j.1524-4725.2000.99233.x
The paper
Gladstone, H. B., Nguyen, S. L., Williams, R., Ottomeyer, T., Wortzman, M., Jeffers, M., & Moy, R. L. (2000). Efficacy of Hydroquinone Cream (USP 4%) Used Alone or in Combination with Salicylic Acid Peels in Improving Photodamage on the Neck and Upper Chest. Dermatologic Surgery. https://doi.org/10.1046/j.1524-4725.2000.99233.x

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.