The DOI matches its Crossref record; 68 of the 69 references it cites were found in a registry or an index.
Effects of depressive symptoms on health-related quality of life in asthma patients
Open accessAbstract
Objective To assess the effects of depressive symptoms on asthma patients' reports of functional status and health-related quality of life.Design Cross-sectional study.Setting Primary care internal medicine practice at a tertiary care center in New York City.Patients We studied 230 outpatients between the ages of 18 and 62 years with moderate asthma.Measurements and main results Patients were interviewed in person in English or Spanish with two health-related quality-of-life measures, the disease-specific Asthma Quality of Life Questionnaire (AQLQ) (possible score range, 1 to 7; higher scores reflect better function) and the generic Medical Outcomes Study SF-36 (general population mean is 50 for both the Physical Component Summary [PCS] score and Mental Component Summary [MCS] score). Patients also completed a screen for depressive symptoms, the Geriatric Depression Scale (GDS), and a global question regarding current disease activity. Stepwise multivariate analyses were conducted with the AQLQ and SF-36 scores as the dependent variables and depressive symptoms, comorbidity, asthma, and demographic characteristics as independent variables. The mean age of patients was 41 +/- SD 11 years and 83% were women. The mean GDS score was 11 +/- SD 8 (possible range, 0 to 30; higher scores reflect more depressive symptoms), and a large percentage of patients, 45%, scored above the threshold considered positive for depression screening. Compared with patients with a negative screen for depressive symptoms, patients with a positive screen had worse composite AQLQ scores (3.9 +/- SD 1.3 vs 2.8 +/- SD 0.8, P <.0001) and worse PCS scores (40 +/- SD 11 vs 34 +/- SD 8, P <.0001) and worse MCS scores (48 +/- SD 11 vs 32 +/- SD 10, P <.0001) scores. In stepwise analyses, current asthma activity and GDS scores had the greatest effects on patient-reported health-related quality of life, accounting for 36% and 11% of the variance, respectively, for the composite AQLQ, and 11% and 38% of the variance, respectively, for the MCS in multivariate analyses.Conclusions Nearly half of asthma patients in this study had a positive screen for depressive symptoms. Asthma patients with more depressive symptoms reported worse health-related quality of life than asthma patients with similar disease activity but fewer depressive symptoms. Given the new emphasis on functional status and health-related quality of life measured by disease-specific and general health scales, we conclude that psychological status indicators should also be considered when patient-derived measures are used to assess outcomes in asthma.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987) · Journal of Chronic Diseases · doi:10.1016/0021-9681(87)90171-8 · Cited by 49,742
Self-citationAn inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
Draper, N. R., & Smith, H. (2005) · Technometrics · doi:10.1198/tech.2005.s303 · Cited by 17,993
Development and validation of a geriatric depression screening scale: a preliminary report
Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1982) · Journal of Psychiatric Research · doi:10.1016/0022-3956(82)90033-4 · Cited by 15,025
David, F. N., & Tukey, J. W. (1977) · Biometrics · doi:10.2307/2529486 · Cited by 12,707
Selective Cortical Undercutting As a Means of Modifying and Studying Frontal Lobe Function in Man
Scoville, W. B. (1949) · Journal of neurosurgery · doi:10.3171/jns.1949.6.1.0065 · Cited by 7,374
Sheikh (1986) · doi:10.1300/j018v05n01_09 · Cited by 7,236
Hahn, G. J., Draper, N. R., & Smith, H. C. (1982) · Technometrics · doi:10.2307/1267833 · Cited by 5,820
Statistical Methods in Medical Research.
Armitage, P. (1972) · Biometrics · doi:10.2307/2556182 · Cited by 5,383
Cited by
Sorted by citations
Moons, P., Budts, W., & Geest, S. D. (2006) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2006.03.015 · Cited by 595
The vital link between chronic disease and depressive disorders.
Chapman, D. P., Perry, G. S., & Strine, T. W. (2005) · Europe PMC (PubMed Central) · Cited by 547
Wang, J., Wu, X., Lai, W., Long, E., Zhang, X., Li, W., Zhu, Y., Chen, C., Zhong, X., Liu, Z., et al. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-017173 · Cited by 486
Long-term mortality and quality of life after prolonged mechanical ventilation*
Chelluri, L., Im, K. A., Belle, S. H., Schulz, R., Rotondi, A. J., Donahoe, M. P., Sirio, C., Mendelsohn, A. B., & Pinsky, M. R. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000098029.65347.f9 · Cited by 361
Mental disorders among adults with asthma: results from the World Mental Health Survey
Scott, K. M., Korff, M. V., Ormel, J., Zhang, M.-Y., Bruffaerts, R., Alonso, J., Kessler, R. C., Tachimori, H., Karam, E. G., Levinson, D., et al. (2007) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2006.12.006 · Cited by 306
Metadata
- Authors
- Mancuso, C. A., Peterson, M. G. E., & Charlson, M. E.
- Affiliations
- Hospital for Special Surgery (US)
- NewYork–Presbyterian Hospital (US)
- Corresponding author
- Mancuso, Carol A.
- Venue
- Journal of General Internal Medicine
- Published
- 2000-05
- Volume
- 15
- Issue
- 5
- Pages
- 301-310
- ISSN
- 0884-8734 (ISSN-L)
- 1525-1497
- PMC
- PMC1495457
- OpenAlex
- W2008421651
- Cited by
- 176
- References
- 69
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 3 · 2022: 6 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 9 · 2015: 4 · 2014: 9 · 2013: 9 · 2012: 11
- FWCI
- 5.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of General Internal Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- depressive symptoms, depression, asthma, health-related quality of life, Asthma Quality of Life Questionnaire, SF-36, Geriatric Depression Scale, comorbidities, functional status, primary care outpatients, depression screening, Spanish-speaking patients, New York City residents, racial and ethnic minorities, socioeconomic status, urban health disparities
- MeSH terms
- Adult, Asthma, Cross-Sectional Studies, Depression, Female, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Socioeconomic Factors, Chi-Square Distribution, Linear Models
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
