CoChat
Sign Up
Cited by 130Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchOccupational exposure and asthma

Impact of depressive symptoms on adult asthma outcomes

Eisner, Mark D., Katz, Patricia P., Lactao, Gretchen, Iribarren, Carlos·2005·Annals of Allergy, Asthma & Immunology
DOI 10.1016/s1081-1206(10)61135-0
Open this paper in CoChat — free account

Abstract

Background Psychological disorders, including depression, are common in adults with asthma. Although depression is treatable, its impact on longitudinal asthma outcomes is not clear.Objective To elucidate the impact of depressive symptoms on patient-centered outcomes and emergency health care use in adults with asthma.Methods We conducted a prospective cohort study of 743 adults with asthma who were recruited after hospitalization for asthma. Depressive symptoms were defined as having a score of 16 or more on the Center for Epidemiologic Studies Depression Scale. We examined the impact of depressive symptoms on patient-centered outcomes (validated severity-of-asthma score, Marks Asthma Quality of Life Questionnaire, and 12-Item Short-Form Health Survey physical component summary score) and on future emergency health care use for asthma ascertained from computerized databases.Results The prevalence of depressive symptoms was 18% (95% confidence interval [CI], 15%-21%) among adults with asthma. Depressive symptoms were associated with greater severity-of-asthma scores after controlling for age, sex, race/ ethnicity, educational attainment, and cigarette smoking (mean score increment, 2.6 points; 95% CI, 1.8-3.4 points). Furthermore, depressive symptoms were associated with poorer asthma-specific quality of life (mean score increment, 19.9 points; 95% CI, 17.7-22.1 points) and poorer physical health status (mean score decrement, 3.7 points; 95% CI, 1.5-5.8 points). Depressive symptoms were associated with a greater longitudinal risk of hospitalization for asthma (hazard ratio, 1.34; 95% CI, 0.98-1.84). After controlling for differences in preventive care for asthma, the relationship was stronger (hazard ratio, 1.45; 95% CI, 1.05-2.0).Conclusion Depressive symptoms are common in adults with asthma and are associated with poorer health outcomes, including greater asthma severity and risk of hospitalization for asthma.

Integrity signals

Registry

Crossref · 10.1016/s1081-1206(10)61135-0

Cites

64 of 64 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • There is a robust relationship between depression and anxiety and poor outcomes in inflammatory diseases.

    “Moreover, there is a robust relationship between depression and anxiety and poor outcomes in inflammatory diseases (Eisner et al., 2005; Satin et al., 2009).”

    From Origin and function of stress-induced IL-6 in murine models (2020) · cites this paper as Eisner et al., 2005

Cites

Flagged first, then by citations

1 of the 65 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Eisner, M. D., Katz, P. P., Lactao, G., & Iribarren, C.
Affiliations
  • University of California, San Francisco (US)
  • Kaiser Permanente (US)
Corresponding author
Eisner, Mark D.
ORCID
Venue
Annals of Allergy, Asthma & Immunology
Publisher
Elsevier BV
Published
2005-05
Volume
94
Issue
5
Pages
566-574
ISSN
1081-1206 (ISSN-L)
DOI
10.1016/s1081-1206(10)61135-0
OpenAlex
W2039110930
Cited by
130
References
65
Citations by year
2025: 3 · 2024: 3 · 2023: 2 · 2022: 7 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 9 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 3 · 2013: 6 · 2012: 13
FWCI
5.42
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Annals of Allergy Asthma & Immunology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Heart, Lung, and Blood Institute (K23HL004201, K23 HL-04201)
Topics
  • Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
Keywords
depressive symptoms, depression, asthma, asthma severity, asthma-specific quality of life, physical health status, emergency department visits, asthma hospitalization, patient-centered outcomes, psychological comorbidity
MeSH terms
Adult, Asthma, California, Depression, Female, Health Status, Hospitalization, Humans, Male, Prospective Studies, Quality of Life, Surveys and Questionnaires, Risk Factors, Cohort Studies, Prevalence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review