Donation reactions among autologous donors
Abstract
Studies of risk factors associated with reactions among autologous blood donors have been limited. Therefore, 2091 autologous and 4737 homologous donations were examined. Donors at greatest risk for reaction were autologous donors who had reactions at first donation; among 45 who made repeat donations for the same surgery, 17 (38%) had repeat reactions. The group least likely to experience reactions were the autologous donors ≥66 years old; they experienced a 1.9≥ percent (6/310) incidence of reactions. More reactions were seen in both autologous and homologous donors in the categories of first‐time donor, female gender, decreasing age, and lower weight. Multiple logistic regression analysis showed that all of these variables were independent predictors of donor reaction, with first‐time donation (odds ratio, 2.4) and female gender (odds ratio, 1.9) being the strongest predictors of reaction. Donor room personnel should be alerted that autologous donors who react at first donation are very likely to react at subsequent donations. Contrary to common concern, elderly autologous donors are least likely to have reactions.
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Many studies have reported higher prevalence of vasovagal reactions among female donors in various donation setups.
“Many studies have reported higher prevalence of vasovagal reactions among the female donors in various donation setup (4,9,16,17,22,23, 24, 25, 26).”
From ADVERSE EVENTS IN BLOOD DONORS: SPECTRUM AND REMEDY (2023) · cites this paper as [23]
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ADVERSE EVENTS IN BLOOD DONORS: SPECTRUM AND REMEDY
Bhushan, R., Gupta, P., Mehra, A., & Iyengar, S. (2023) · PARIPEX-Indian Journal of Research · doi:10.36106/paripex/1800303
- Authors
- McVay, P. A., Andrews, A., Kaplan, E. B., Black, D. B., Stehling, L. C., Strauss, R. G., & Toy, P. T. C. Y.
- Affiliations
- University of California, San Francisco (US)
- American Red Cross (US)
- University of New Mexico (US)
- University of Iowa (US)
- San Francisco General Hospital (US)
- Corresponding author
- Toy, P.T.C.Y.
- Venue
- Transfusion
- Publisher
- Wiley
- Published
- 1990-03-04
- Volume
- 30
- Issue
- 3
- Pages
- 249-252
- ISSN
- 0041-1132 (ISSN-L)
- 1537-2995
- OpenAlex
- W2083554346
- Cited by
- 97
- References
- 2
- Citations by year
- 2023: 1 · 2021: 1 · 2020: 4 · 2019: 1 · 2017: 2 · 2016: 3 · 2015: 1 · 2013: 1 · 2012: 1
- FWCI
- 16.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Transfusion (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5k07hl001426-02, 5k07hl001270-05, 5k07hl001257-05)
- National Heart, Lung, and Blood Institute (K07-HL01426, K07 HL01257, K07 HL01270)
- Topics
- Social Sciences › Business, Management and Accounting › Management of Technology and Innovation › Blood donation and transfusion practices
- Health Sciences › Medicine › Biochemistry › Blood transfusion and management
- Health Sciences › Medicine › Hematology › Blood groups and transfusion
- Keywords
- autologous blood donation, donor reactions, risk factors, first-time donors, female donor, age, weight
- MeSH terms
- Adolescent, Aging, Blood Donors, Blood Transfusion, Autologous, Blood Vessels, Female, Humans, Risk Factors, Vagus Nerve, Vascular Diseases
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