The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Evolving a lingua franca and associated software infrastructure for computational systems biology: the Systems Biology Markup Language (SBML) project
Abstract
Biologists are increasingly recognising that computational modelling is crucial for making sense of the vast quantities of complex experimental data that are now being collected. The systems biology field needs agreed-upon information standards if models are to be shared, evaluated and developed cooperatively. Over the last four years, our team has been developing the Systems Biology Markup Language (SBML) in collaboration with an international community of modellers and software developers. SBML has become a de facto standard format for representing formal, quantitative and qualitative models at the level of biochemical reactions and regulatory networks. In this article, we summarise the current and upcoming versions of SBML and our efforts at developing software infrastructure for supporting and broadening its use. We also provide a brief overview of the many SBML-compatible software tools available today.
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Cites
Cytoscape: A software Environment for integrated models of biomolecular interaction networks
Shannon, P., Markiel, A., Ozier, O., Baliga, N. S., Wang, J. T., Ramage, D., Amin, N., Schwikowski, B., & Ideker, T. (2003) · Genome Research · doi:10.1101/gr.1239303 · Cited by 51,888
Network motifs: simple building blocks of complex networks.
Milo, R., Shen-Orr, S., Itzkovitz, S., Kashtan, N., Chklovskii, D., & Alon, U. (2002) · Science · doi:10.1126/science.298.5594.824 · Cited by 7,368
From molecular to modular cell biology.
Hartwell, L. H., Hopfield, J. J., Leibler, S., & Murray, A. W. (1999) · Nature · doi:10.1038/35011540 · Cited by 3,632
Computer Methods for Ordinary Differential Equations and Differential-Algebraic Equations
Ascher, U. M., & Petzold, L. R. (1998) · doi:10.1137/1.9781611971392 · Cited by 2,403
Computational systems biology.
Kitano, H. (2002) · Nature · doi:10.1038/nature01254 · Cited by 2,209
Self-citationA N EW A PPROACH TO D ECODING L IFE : Systems Biology
Ideker, T., Galitski, T., & Hood, L. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.343 · Cited by 1,664
E-CELL: software environment for whole-cell simulation
Tomita, M., Hashimoto, K., Takahashi, K., Shimizu, T. S., Matsuzaki, Y., Miyoshi, F., Saito, K., Tanida, S., Yugi, K., Venter, J. C., et al. (1999) · Bioinformatics · doi:10.1093/bioinformatics/15.1.72 · Cited by 764
Kholodenko, B. N. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01197.x · Cited by 643
Web-based kinetic modelling using JWS Online
Olivier, B. G., & Snoep, J. L. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth200 · Cited by 326
Motifs, modules and games in bacteria
Wolf, D. M., & Arkin, A. P. (2003) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(03)00033-x · Cited by 303
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COBRApy: COnstraints-Based Reconstruction and Analysis for Python
Ebrahim, A., Lerman, J. A., Palsson, B. O., & Hyduke, D. R. (2013) · BMC Systems Biology · doi:10.1186/1752-0509-7-74 · Cited by 1,378
Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology
Karp, P. D., Paley, S. M., Krummenacker, M., Latendresse, M., Dale, J. M., Lee, T. J., Kaipa, P., Gilham, F., Spaulding, A., Popescu, L., et al. (2010) · Briefings in Bioinformatics · doi:10.1093/bib/bbp043 · Cited by 694
Corpus annotation for mining biomedical events from literature
Kim, J.-D., Ohta, T., & Tsujii, J. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-10 · Cited by 395
Rules for Modeling Signal-Transduction Systems
Hlavacek, W. S., Faeder, J. R., Blinov, M. L., Posner, R. G., Hucka, M., & Fontana, W. (2006) · Science's STKE · doi:10.1126/stke.3442006re6 · Cited by 350
Self-citationBio-PEPA: A framework for the modelling and analysis of biological systems
Ciocchetta, F., & Hillston, J. (2009) · Theoretical Computer Science · doi:10.1016/j.tcs.2009.02.037 · Cited by 335
Metadata
- Authors
- Hucka, M., Finney, A., Doyle, J. C., Kitano, H., Kovitz, B. L., Shapiro, B. E., Funahashi, A., Matthews, J., Bornstein, B. J., Keating, S. M., & Schilstra, M. J.
- Venue
- Systems Biology
- Published
- 2004-06-01
- Volume
- 1
- Issue
- 1
- Pages
- 41-53
- ISSN
- 1741-2471 (ISSN-L)
- 1741-248X
- OpenAlex
- W2100525485
- Cited by
- 232
- References
- 11
- FWCI
- 6.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Hucka, M., Finney, A., Doyle, J. C., Kitano, H., Kovitz, B. L., Shapiro, B. E., Funahashi, A., Matthews, J., Bornstein, B. J., Keating, S. M., & Schilstra, M. J. (2004). Evolving a lingua franca and associated software infrastructure for computational systems biology: the Systems Biology Markup Language (SBML) project. Systems Biology. https://doi.org/10.1049/sb%3A20045008
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