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Cited by 481

The DOI matches its Crossref record; 131 of the 131 references it cites were found in a registry or an index.

A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer

Open access
Huang, Chih-Yang, Ju, Da-Tong, Chang, Chih-Fen, Muralidhar Reddy, P., Velmurugan, Bharath Kumar·2017·BioMedicine

Abstract

Lung cancer is the leading cause of cancer deaths worldwide, and this makes it an attractive disease to review and possibly improve therapeutic treatment options. Surgery, radiation, chemotherapy, targeted treatments, and immunotherapy separate or in combination are commonly used to treat lung cancer. However, these treatment types may cause different side effects, and chemotherapy-based regimens appear to have reached a therapeutic plateau. Hence, effective, better-tolerated treatments are needed to address and hopefully overcome this conundrum. Recent advances have enabled biologists to better investigate the potential use of natural compounds for the treatment or control of various cancerous diseases. For the past 30 years, natural compounds have been the pillar of chemotherapy. However, only a few compounds have been tested in cancerous patients and only partial evidence is available regarding their clinical effectiveness. Herein, we review the research on using current chemotherapy drugs and natural compounds (Wortmannin and Roscovitine, Cordyceps militaris, Resveratrol, OSU03013, Myricetin, Berberine, Antroquinonol) and the beneficial effects they have on various types of cancers including non-small cell lung cancer. Based on this literature review, we propose the use of these compounds along with chemotherapy drugs in patients with advanced and/or refractory solid tumours.

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Metadata

Authors
Huang, C.-Y., Ju, D.-T., Chang, C.-F., Muralidhar Reddy, P., & Velmurugan, B. K.
Venue
BioMedicine
Published
2017-11-24
Volume
7
Issue
4
Pages
23
ISSN
  • 2211-8020 (ISSN-L)
  • 2211-8039
OpenAlex
W2768610432
Cited by
481
References
131
FWCI
29.77
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer. https://app.cochat.ai/papers/10.1051/bmdcn/2017070423
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Huang, C.-Y., Ju, D.-T., Chang, C.-F., Muralidhar Reddy, P., & Velmurugan, B. K. (2017). A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer. BioMedicine. https://doi.org/10.1051/bmdcn/2017070423

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