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“In this meta-analysis of 13 cohorts, including 21,688 individuals selected because of CKD, we found that lower eGFR and higher albuminuria were each independently associated with mortality and ESRD.”
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“9 billion in Medicare costs alone) for the treatment of an estimated 500,000 patients in the US [43].”
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“Limitations The incidence and prevalence of end-stage renal disease in Taiwan is among the highest in the world.(29) Although we performed a large national cohort study, our study has several limitations.”
BackgroundLow Bone Mineral Density and Fractures in Long-Term Hemodialysis Patients: A Meta-Analysis
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BackgroundVascular Access Choice in Incident Hemodialysis Patients
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“5 years for those 60 to 64 years of age suggesting that survival especially in older patients is comparable only to that of patients with lung cancer [5].”
BackgroundIL-1β Receptor Antagonist Reduces Inflammation in Hemodialysis Patients
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“With respect to patient-reported outcomes, changes in quality of life over time are similar among PD vs. HD patients, although PD patients report greater satisfaction with care.15,20 PD patients require fewer access procedures than patients receiving HD with a CVC.21 PD also preserves residual renal function to a grea…”
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“Patients with CKD exhibit accelerated atherosclerosis and cardiovascular disease which are the primary cause of death in this population [35, 36].”
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“In the United States, diabetes accounts for 45% of incident end-stage renal disease (ESRD).(2) In 2006, the US federal government estimated cost was $23 billion for ESRD treatment, and the corresponding CKD treatment cost was $49 billion.”
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“Moreover, patient survival in diabetics on maintenance dialysis is lower than in non-diabetic patients with end-stage renal disease due to other renal diseases [6].”
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“Background Cardiovascular events (CVEs) are the leading causes of death among dialysis patients, with mortality rates 7 to 30 times higher than in the general population [1, 2].”
BackgroundPatients’ perspectives on dialysis decision-making and end-of-life care
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“49-52 The mechanisms by which hyperphosphatemia contributes to the initiation and progression of vascular calcification include (1) transformation of vascular smooth muscle cells (VSMCs) from a contractile to an osteochondrogenic phenotype and mineralization of VSMC matrix through sodiumdependent phosphate co-transpor…”
Vitamin E tocotrienol supplementation improves lipid profiles in chronic hemodialysis patients
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“Dialysis duration (mo) 33 (12-48) 29 (15-62) Cause of ESRD (%) Diabetes 33 33 Hypertension 15 25 Glomerulonephritis 8 20 Other 20 10 Unknown 25 13”
Aldosterone and cortisol affect the risk of sudden cardiac death in haemodialysis patients
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“Patients with renal failure, regardless of whether or not they have atrial fibrillation, have high rates of cardiovascular events that account for about half of the group mortality [117,191].”
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“The mortality rate of end-stage renal disease (ESRD) patients is t least 20–30 times higher than age- and gender-matched healthy ontrols; cardiovascular and cerebrovascular diseases resulting rom an accelerated process of atherosclerosis comprise the two eading causes ofmorbidity andmortality [1].”
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“Platelet reactivity plays a central role in the genesis of thrombosis and thromboembolic events, especially in atherosclerotic cardiovascular disease—the leading cause of death in ESRD and CHF patients (3).”
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“Infection is the second leading cause of mortality and a major cause of morbidity in ESRD patients [5].”
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“Thus, loss of nephrons is permanent and ultimately leads to endstage kidney disease (ESKD), where patients require renal replacement therapies, such as hemodialysis, associated with high mortality and morbidity.(58) In addition, there are limited human disease models for the development of treatment methods and identi…”
BackgroundCognitive Function and Dialysis Adequacy: No Clear Relationship
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“Background More than 600,000 patients in the United States have end-stage renal disease (ESRD), with approximately 450,000 patients undergoing hemodialysis (HD) [1].”
BackgroundInfluentialHSP27 and HSP70 serum and urine levels in patients suffering from chronic kidney disease
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“Infection is the second leading cause of mortality and a major cause of morbidity in ESRD patients [3].”
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“Diabetes is the most common cause of end stage renal disease (ESRD) in the United States and most other developed and emerging countries (1).”
BackgroundInfluentialβ-Blocker Dialyzability in Maintenance Hemodialysis Patients
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A Review of Cannabis in Chronic Kidney Disease Symptom Management
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“Cardiovascular disease accounts for 50 % of deaths in patients with ESRD with near 20 % attributed to CAD [24].”
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Meeting the challenges of the new K/DOQI guidelines
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“The increased CV risk associated with DM has been demonstrated to not only affect ESKD patients, but also lead to increased mortality rates across the general population [5 , 8 –10 ].”
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“CVD is associated with high morbidity and mortality in dialysis patients [24], yet there are key phenotypic differences that exist between CVD in patients with CKD compared to the general population [25] which may explain our findings.”
BackgroundCardiac imaging for the assessment of patients being evaluated for kidney or liver transplantation
Parikh, K., Appis, A., & Doukky, R. (2014) · Journal of Nuclear Cardiology · doi:10.1007/s12350-014-9997-y · Cited by 41 · see citing works
Bacteremia in Hemodialysis and Peritoneal Dialysis Patients
Wang, I., Chang, Y.-C., Liang, C., et al. (2012) · Internal Medicine · doi:10.2169/internalmedicine.51.7111 · Cited by 40 · see citing works
“A review of the US Renal Data System (USRDS) indicated that first year hospital admission rates for bacteremia were higher for hemodialysis (HD) patients than for peritoneal dialysis (PD) patients (1, 6).”
BackgroundInfluentialBeaubien‐Souligny, W., Kontar, L., Blum, D., et al. (2019) · Kidney International Reports · doi:10.1016/j.ekir.2019.07.003 · Cited by 40 · see citing works
“D espite considerable technological advances over the past 30 years, mortality among maintenance dialysis recipients remains unacceptably high.(1) Although partially attributable to classic cardiovascular risk factors that are commonly found in patients with chronic kidney disease, “nontraditional” risk factors unique…”
BackgroundGwon, M., An, H., Kim, J., Kim, W., Gu, H., Kim, H., Leem, J., Jung, H. J., & Park, K. (2019) · The FASEB Journal · doi:10.1096/fj.201901307rr · Cited by 40 · see citing works
End-Stage Kidney Disease After Pediatric Nonrenal Solid Organ Transplantation
Ruebner, R. L., Reese, P. P., Denburg, M., Abt, P. L., & Furth, S. L. (2013) · PEDIATRICS · doi:10.1542/peds.2013-0904 · Cited by 38 · see citing works
“73 m(2), n (%) $90 8069 (49) 5358 (60) 1617 (29) 586 (61) 444 (46) 64 (41) 60–89 3923 (24) 1848 (21) 1600 (29) 158 (16) 283 (30) 34 (22) 30–59 1783 (11) 752 (8) 877 (16) 41 (4) 103 (11) 10 (6) ,30 or acute dialysis 778 (5) 355 (4) 368 (7) 18 (2) 33 (3) 4 (3) Missing 2051 (12) 645 (7) 1107 (20) 160 (17) 94 (10) 45 (29)”
Impact of age on survival predictability of bone turnover markers in hemodialysis patients
Lertdumrongluk, P., Lau, W. L., Park, J., et al. (2013) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gft290 · Cited by 38 · see citing works
“Cardiovascular disease is the leading cause of mortality in dialysis patients [1].”
BackgroundIimori, S., Noda, Y., Okado, T., Naito, S., Toda, T., Chida, Y., Kuwahara, M., Ando, R., Nishio, Y., Maeda, Y., et al. (2013) · BMC Nephrology · doi:10.1186/1471-2369-14-152 · Cited by 37 · see citing works
“CVD risk factors, such as hypertension, diabetes and dyslipidemia, tend to be highly prevalent and poorly controlled in patients with CKD [8].”
Hemodialysis in children with end-stage renal disease
Müller, D. N., & Goldstein, S. L. (2011) · Nature Reviews Nephrology · doi:10.1038/nrneph.2011.124 · Cited by 35 · see citing works
Park, J. Y., Kim, M., Han, S. S., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127240 · Cited by 36 · see citing works
Risk Factors for End-Stage Kidney Disease After Pediatric Liver Transplantation
Ruebner, R. L., Reese, P. P., Denburg, M., et al. (2012) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2012.04270.x · Cited by 36 · see citing works
“Living donor, n(%) 1210 (14) Location at time of liver transplant, n(%) Hospitalized, intensive care unit 2427 (27) Hospitalized, non-intensive care unit 1637 (18) Not hospitalized 4905 (55) Immunosuppressive therapy at time of transplant, n(%) Cyclosporine-based 2353 (26) Tacrolimus-based 5724 (64) Other 209 (2) Miss…”
BackgroundHarduin, L. D. O., Barroso, T. A., Guerra, J. B., Filippo, M. G., de Almeida, L. C., de Castro-Santos, G., Oliveira, F. A. C., Cavalcanti, D. E. T., Procópio, R. J., Lima, E. C., et al. (2023) · Jornal Vascular Brasileiro · doi:10.1590/1677-5449.202300522 · Cited by 35 · see citing works
Kjærgaard, K. D., Peters, C. D., Jespersen, B., et al. (2014) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2014.05.011 · Cited by 35 · see citing works
“78 0 [0-15]”
Feyssa, E. L., Jones-Burton, C., Ellison, G. L., et al. (2009) · Journal of the National Medical Association · doi:10.1016/s0027-9684(15)30822-1 · Cited by 35 · see citing works
- Authors
- Collins, A. J., Foley, R. N., Herzog, C., Chavers, B. M., Gilbertson, D., Ishani, A., Kasiske, B. L., Liu, J., Mau, L.-W., McBean, M., Murray, A., St. Peter, W., Guo, H., Li, Q., Li, S., Li, S., Peng, Y., Qiu, Y., Roberts, T., Skeans, M., Snyder, J., Solid, C., Wang, C., Weinhandl, E., Zaun, D., Arko, C., Chen, S.-C., Dalleska, F., Daniels, F., Dunning, S., Ebben, J., Frazier, E., Hanzlik, C., Johnson, R., Sheets, D., Wang, X., Forrest, B., Constantini, E., Everson, S., Eggers, P. W., & Agodoa, L.
- Affiliations
- United States Department of Veterans Affairs (US)
- ORCID
- Venue
- American Journal of Kidney Diseases
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 55
- Issue
- 1
- Pages
- A6-A7
- ISSN
- 0272-6386 (ISSN-L)
- PMC
- PMC2829836
- OpenAlex
- W1955298113
- Cited by
- 436
- References
- 0
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 12 · 2023: 18 · 2022: 19 · 2021: 22 · 2020: 20 · 2019: 23 · 2018: 35 · 2017: 25 · 2016: 34 · 2015: 40 · 2014: 29 · 2013: 42 · 2012: 37
- FWCI
- 19.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Kidney Diseases (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (HHSN 267 2007 15002C/N01-DK-7-5002, HHSN267200715002C)
- Topics
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
- Keywords
- chronic kidney disease, end-stage renal disease, acute kidney injury, mortality risk, blood pressure control, lipid control, health care costs, morbidity, NHANES
- MeSH terms
- Chronic Disease, Medicare, Renal Dialysis, Humans, Kidney Diseases, United States, Kidney Transplantation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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