Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat
Wallace, John L., Caliendo, Giuseppe, Santagada, Vincenzo, Cirino, Giuseppe, Fiorucci, Stefano·2007·Gastroenterology
Cited by (270)
Items 201–270 of 270
- Panax Notoginseng Saponins Ameliorates Coxsackievirus B3-Induced Myocarditis by Activating the Cystathionine-γ-Lyase/Hydrogen Sulfide PathwayLulu Pan, Yuanhai Zhang, Jia‐Cheng Lu, Zhimin Geng, Lianhong Jia, Xing Rong, Zhenquan Wang, Qifeng Zhao, Rongzhou Wu, Maoping Chu et al. · 2015 · Journal of Cardiovascular Translational Research
- Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in MiceSilvia Abigail Coavoy-Sánchez, A Cerqueira, Simone A. Teixeira, Vincenzo Santagada, Giorgia Andreozzi, Angela Corvino, Antonia Scognamiglio, Rosa Sparaco, Giuseppe Caliendo, Beatrice Severino et al. · 2023 · Pharmaceutics
- The anti-inflammatory effect of hydrogen sulphide on acute necrotizing pancreatitis in ratsKutay Sağlam, Etem Alhan, Serdar Türkyılmaz, Birgül Vanizor, Cengiz Erçín · 2017 · Turkish Journal of Surgery
- Design, Synthesis, and Neuroprotective Effects of H2S-Donor-Peptide Hybrids on Hippocampal Neuronal CellsEui Kyun Jeong, Baskar Selvaraj, Shyaka Clovis, Yun Jeong Son, Tae Hoo Park, Veeramanoharan Ashokkumar, Hoe-In Kim, Ki‐Yeon Yoo, Jae Wook Lee, Chung‐Min Park · 2022 · Free Radical Biology and Medicine
- Functional promoter polymorphisms direct the expression of cystathionine gamma-lyase gene in mouse models of essential hypertensionVinayak Gupta, Piyushkumar R. Kapopara, Abrar Ali Khan, Vikas Arige, Lakshmi Subramanian, Parshuram J. Sonawane, Binu Kandathilparambil Sasi, Nitish R. Mahapatra · 2016 · Journal of Molecular and Cellular Cardiology
- Potent Bile Acid Microbial Metabolites Modulate Clostridium perfringens VirulenceTahrir Alenezi, Ying Fu, Bilal Alrubaye, Thamer Alanazi, Ayidh M. Almansour, Hong Wang, Xiaolun Sun · 2023 · Pathogens
- Review of Hydrogen Sulfide Based on Its Activity Mechanism and Fluorescence SensingJinlong Zhang, Quan Jing, Fei Gao, Fuxin Zhang, Dong Pei, Duolong Di, Jun Hai · 2024 · Targets
- ADT‐OH synergistically enhanced the antitumor activity of celecoxib in human colorectal cancer cellsHuangru Xu, Ping Li, Hailin Ma, Yuanhao Tan, Xiaoyang Wang, Fangfang Cai, Jiaqi Xu, Huisong Sun, Hongqin Zhuang, Zi‐Chun Hua · 2023 · Cancer Medicine
- Toward More GI-Friendly Anti-Inflammatory MedicationsJohn Lawrence Wallace, Gilberto De Nucci, Oksana Sulaieva · 2015 · Current Treatment Options in Gastroenterology
- Regulation of gastric acid secretion by the serum and glucocorticoid inducible kinase isoform SGK3Venkanna Pasham, Anand Rotte, Madhuri Bhandaru, Melanie Eichenmüller, Henning Fröhlich, Andreas F. Mack, Diwakar Bobbala, Wenting Yang, David Pearce, Florian J.W. Lang · 2010 · Journal of Gastroenterology
- Gastro-Protective and Anti-Oxidant Potential of Althaea officinalis and Solanum nigrum on Pyloric Ligation/Indomethacin-Induced Ulceration in RatsSameh S. Zaghlool, Ali A. Abo-Seif, Mohamed Abdelaaty Rabeh, Usama Ramadan Abdelmohsen, Basim Anwar Shehata Messiha · 2022 · Vide Leaf, Hyderabad eBooks
- Omega3 Fatty Acids Intake Versus Diclofenac in Osteoarthritis Induced in Experimental ratsMohammed M. El-Seweidy, Sousou I. Ali, Sahar E. Elsweify, Abdelmoneim A. Ali, Mai M. Mashhour · 2017 · Functional Foods in Health and Disease
- Medicinal Chemistry and Therapeutic Applications of the Gasotransmitters NO , CO , and H 2 S and their ProdrugsCsaba Szabó · 2010 · Wiley eBooks
- NSAID-induced enteropathy: the current state of the problemAndrey А. Svistunov, Mikhail A. Osadchuk, Natalia V. Kireeva, A. Khudarova, Е. Е. Ачкасов · 2018 · Terapevticheskii arkhiv
- Reconnecting the roots of hydrogen sulfide (H2S) with medicinal chemistry: Lessons accomplished and challenges so farChahat, Bhupinder Kumar, Shankar Gupta, Muhammad Wahajuddin, Gaurav Joshi · 2025 · Bioorganic Chemistry
- Cyanidin-3-O-Glucoside Improves Colonic Motility During Severe Acute Pancreatitis by Inhibiting the H2S-Regulated AMPK/mTOR PathwayWei Lian, Wensheng Chen · 2020 · Drug Design Development and Therapy · Retracted
- Multiple Roles of H2S in Inflammation: A New Class of Therapeutics?Ling Li, Mohamed Shirhan Bin Mohamed Atan, Philip Keith Moore · 2013 · Springer eBooks
- The role of hydrogen sulphide in lung diseasesChih‐Hung Wu · 2013 · Bioscience Horizons The International Journal of Student Research
- Efficacy, safety and tolerance of subcutaneous injection of high dosages of diclofenac in patients with neuropathic non-cancer pain and neuropathic cancer pain: Data from a clinical settingFrancesco Amato, Erika Morrone, Giuseppina Lacquaniti · 2015 · European Journal of Inflammation
- Effect of Ketoprofen and ATB‐352 on the Immature Human IntestineMarie‐Pier Thibault, Éric Tremblay, John Lawrence Wallace, Jean‐François Beaulieu · 2019 · Journal of Pediatric Gastroenterology and Nutrition
- Growth inhibitory effect of KYKZL-1 on Hep G2 cells via inhibition of AA metabolites and caspase-3 pathway and cell cycle arrestJing Cheng, Yi-Fang Du, Zhi-Yi Xiao, Li-Li Pan, Wei Li, Lin Huan, Zhunan Gong, Shaohua Wei, Shiqian Huang, Xun Wei et al. · 2013 · Toxicology and Applied Pharmacology
- Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse modelPing Jiang, Zhi-Shen Xu, Baiquan Xiao, Zhong Ze Han, Jiehong Huang, Jian-Bang Xu, Zhao‐Rong Lun, Wenliang Zhou · 2017 · Molecular Medicine Reports
- Drug-Induced Liver InjuryBetty S. Apica, W.M. Lee · 2014 · Elsevier eBooks
- Discovery of Novel Tofacitinib–ADTOH Molecular Hybridization Derivatives for the Treatment of Ulcerative ColitisYi Mou, Shuai Wen, Yan Wang, Yao Zhao, Ying-Ping Li, Hong-Kai Sha, Li-Juan Gui, Zhengyu Jiang, Xiang-Ming Xu · 2025 · Antioxidants
- Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory painIvo S.F. Melo, Victor P. Ziviani, Bárbara C. M. Barbosa, Felipe F. Rodrigues, Roger R.L. Silva, Leonardo da Silva Neto, Ângelo de Fátima, Isabela Costa César, Renes R. Machado, Márcio M. Coelho · 2022 · European Journal of Pharmacology
- HPLC determination of novel dithiolethione containing drugs and its application for in vivo studies in ratsDaniela Giustarini, Elena Perrino, Valerio Tazzari, Ranieri Rossi · 2009 · Journal of Chromatography B
- Lyophilized Aspirin with Trehalose May Decrease the Incidence of Gastric Injuries in Healthy DogsLee‐Shuan Lin, Yuko Kayasuga, Nobuyuki Shimohata, Hiroyuki Kamata, Shigeki Suzuki, Ryosuke Echigo, Manabu MOCHIZUKI, Ung‐il Chung, Nobuo Sasaki · 2012 · Journal of Veterinary Medical Science
- NO-H 2 S-Releasing Chimeras as a Multifaceted Approach to Cancer TherapyKhosrow Kashfi, Mahnoush Esmaili · 2017 · Elsevier eBooks
- NO‐, CO‐, and H2S‐Based MetallopharmaceuticalsRAM CHARITRA MAURYA, Jan Mohammad Mir · 2020 · Wiley eBooks
- Hydrogen Sulfide: Its Production, Release and FunctionsKyle L. Flannigan, John Lawrence Wallace · 2013 · Springer eBooks
- Gaseous mediators (H2S, NO and CO) a new approach in gastrointestinal protectionElizabeth Arlen Pineda‐Peña, Aracely Evangelina Chávez‐Piña · 2023 · Mexican Journal of Medical Research ICSA
- A second polymorph of 3H-1,2-benzodithiole-3-thioneKhaled Boukebbous, El Adoui Laifa, Aimery de Mallmann, Mostafa Taoufik · 2016 · IUCrData
- Activity evaluation of multifunctional H2S donors for anti-inflammatory, cardioprotective, and hepatoprotective applicationsD Wang, Yujie Meng, Yi‐Hong Liu · 2025 · Frontiers in Chemistry
- Hydrogen Sulfide: A Multitarget Therapeutic for Neuroinflammation in Neurodegenerative DiseasesYuqing Zhang, Qiong Zhang, Li Yang, Yang Fan, Peng Zheng, Tiangui Liu, Xin Gao, Zhelei Ren, Xinpeng Wang, Bowen Zhou et al. · 2026 · Research
- Intelligent sulfur-based delivery systems for controlled hydrogen sulfide therapeutics: Progress and prospectsYiQing Chen, Ziqing Mao, Huiwang Lian, Qiguang Li, Chuang Wang, Yang Li · 2026 · Journal of Controlled Release
- Hydrogen Sulfide in Analgesia: The Journey from Gas to Hybrids and BeyondHong-Qing Feng, Xiaomin Han, Hao-Yun Chen, Wen-Jing Gao, Tao Zhuang · 2026 · Journal of Medicinal Chemistry
- Lymphocyte Hydrogen Sulfide Production Predicts Coronary Artery Lesions in Children with Kawasaki Disease: A Preliminary, Single-Center StudyJing Lin, Huacai Zhao, Fuyong Jiao, Lei Ma, Weiqing Wang, Le Ma · 2019 · Journal of Tropical Pediatrics
- Contribution of neuroinflammation, resolution, and neuroprotection in neuropsychiatric diseasesA. A. Farooqui · 2021 · Elsevier eBooks
- Contribution of neuroinflammation, resolution, and neuroprotection in neurotraumatic diseasesA. A. Farooqui · 2021 · Elsevier eBooks
- Hydrogen Sulfide Pathway and CancerAngela Ianaro, Giuseppe Cirino · 2016 · Elsevier eBooks
- Towards Gaseous Mediator Hybrid DrugsJohn F. Gilmer · 2017 · Elsevier eBooks
- Trends in development of gi-safe anti-inflammatory drugsOksana Sulaieva, John Lawrence Wallace · 2017 · Clinical Medicine (Russian Journal)
- Mitochondria-Targeted Hydrogen Sulphide Donors Protect Renal Cells From Hypoxia Re-Oxygenation InjuryGhaleb Anas Aboalsamh · 2015 · Scholarship@Western (Western University)
- Hydrogen Sulfide (H2S ) - Poison Gas to Signaling Molecule in Regulation of Human BiologyShivani Chauhan · 2018 · Journal of pharmacology & clinical research
- NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; COMPARATIVE ANALYSISSyeda Amber Zaidi, Syed Mohsin Turab, Afzal Qasim, Shah Nawaz Jamali · 2016 · The Professional Medical Journal
- New strategy for gastrointestinal protection based on gaseous mediators applicationOksana Sulaieva, John Lawrence Wallace · 2016 · Russian Journal of Gastroenterology Hepatology Coloproctology
- Efficacy of a Peruvian Botanical Remedy (Sabell A4+) for Treating Liver Disease and Protecting Gastric Mucosal IntegrityMark G. Swain, John Lawrence Wallace, D. Lorne Tyrrell, José Cabanillas, Steven Aung, Hongqun Liu, Lindsay Finnie-Carvalho, Grishma Shrestha, Hugh A. Semple, Francis H. Y. Green · 2019 · Evidence-based Complementary and Alternative Medicine
- Synthesis, Characterization, and Evaluation of Small Molecule-based Fluorogenic Probes for the Detection of Cellular ThiolsRasika R. Nawimanage · 2015
- Current Research Strategies for Designing Safer NSAIDsZaher A. Radi · 2012 · Wiley eBooks
- Synthesis of polymers with the potential to release H2STyler R. Long, F. Christopher Pigge, Aliasger K. Salem, Ned B. Bowden, Mark Allen Arnold, James B. Gloer · 2014
- [Advances in hydrogen sulfide and hydrogen sulfide-releasing drugs].Xiao-li Wang, Zhaoya Wang, Xiao-qiang Guo, Yihua Zhang, Jian Yin · 2016 · PubMed
- Estudo dos efeitos do composto GYY-4137, um doador de sulfeto de hidrogênio (H2S), na sinovite aguda induzida por carragenina na articulação temporomandibular de ratos.Flávia B.C. Lira · 2016
- NSAID Prodrugs with Improved Anti-inflammatory Activity and Low Ulcerogenicity: Wake Up Call to Pharmaceutical Companies and Health AuthoritiesSarthak Jain · 2012 · ERA: Education and Research Archive (University of Alberta)
- Endocannabinoid modulation of secretory and inflammatory causes of gastric pathologyMolly S. Crowe · 2016
- Paper-Based Analytical Device for Rapid Naked-Eye Detection of Sulfide in Water SamplesLingzhi Zhao · 2020 · Journal of the chemical society of pakistan
- The gastroprotective effect of alpinia officinarum extract on indomethacin-induced topical injuries in RGM-1 Cells: Involvement of H+/K+-ATPase- and mitochondrial-mediated apoptosisJunqing Zhang, Li Li, Jingwen Gong, Hailong Li, Mingyan Zhou, Yinfeng Tan · 2021 · Pharmacognosy Magazine
- The potential role of sulfur amino acids in the acute inflammatory responseGerardo Medina · 2021 · Mspace (University of Manitoba)
- DICLOFENAC POTASSIUMHuma Ali, Farya Zafar, Saba Ajaz Baloch, Hina Hasnain, Safila Naveed, Ghazala Raza Naqvi · 2016 · The Professional Medical Journal
- Comparative Effects of Single Agent Rectal Diclofenac versus its Combination with Intramuscular Pentazocine on Post Caesarean Section Pain Relief in a Tertiary Institution in Southern Nigeria2019 · ARC Journal of Gynecology and Obstetrics
- H 2 S-releasing Molecules in Pharmaceutical DevelopmentMaria Dichiara, Emanuele Amata · 2022 · Future Medicinal Chemistry
- Influence of PTGS1 gene polymorphisms on efficiency and safety of post-operative Ketorolac treatment of uncomplicated acute calculus cholecystitisAndranik Alexandrovich Muradian, Dmitry Alekseevich Sychev, Dmitry Alekseevich Blagovestnov, Петров Демьян Игоревич, Скукин Дмитрий Сергеевич, Irina V. Epifanova, Zhannet Alimovna Sozaeva, Anastasia Alekseevna Kachanova, Н. П. Денисенко, Sh. P. Abdullaev et al. · 2022 · Экспериментальная и клиническая гастроэнтерология
- Efeito de compostos doadores de sulfeto de hidrogênio (H2S) na dermatite atópica experimental induzida em camundongos.Silvia Abigail Coavoy-Sánchez · 2021 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- A kén-hidrogén protektív hatásmechanizmusainak vizsgálata TNBS-indukált patkány colitis modellbenSzilvia Török · 2022
- Сучасні підходи до ведення хворих з НПЗП-індукованими ураженнями тонкої кишкиС. М. Ткач, Balabantseva Hp, A. R. Levchenko · 2014 · Likarska sprava
- Avaliação farmacológica do potencial analgésico e anti-inflamatório de doadores de sulfeto de hidrogênio (H2S) na dor orofacial.Janaíne Prata de Oliveira · 2023 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Protecting the gastrointestinal mucosaMelinda Ugocsai · 2025
- Dietary Cyclic Organosulfides as H2S Donors: Modulating NF-κB Signaling Pathway to Exert Anti-Inflammatory Activity in RAW264.7 MacrophagesMolan Zhang, Yujia Cao, Yuxuan Huang, Bin Leng, Yi Lin, Dong Liang, Jinsong Bian, Lijun You, Dejian Huang · 2026 · Journal of Future Foods
- New 3H-1,2-Dithiole-3-thione derivatives: Design and synthesis, H2S-release profile, in vitro anticancer activity, and in silico multi-target assessmentSemra Altunsoy, Yakup Berkay Yılmaz, Tuğba Güngör, Hazal Nazlıcan Atalay, Mine Isaoglu, Serdar Durdağı, Mehmet Ay, Tugba Boyunegmez Tumer · 2026 · Molecular Diversity
- Discovery of Novel Anethole Trithione Derivatives Targeting SQR Pathway to Induce Mitochondrial Uncoupling for Stroke TreatmentPeng Song, Yuan Li, Xiaohan Song, Yibing Wang, Lu Zhang, Zhenwei Zhang, Xuelian Ren, X M Yan, D D Zhang, Ya-qin Pei et al. · 2026 · Journal of Medicinal Chemistry
- BindingDB Entry 50047197: Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies.BindingDB · 2017 · UC San Diego