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Microsatellite Instability in Colorectal Cancer
Open accessAbstract
Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatch repair activity. MSI is detected in about 15% of all colorectal cancers; 3% are of these are associated with Lynch syndrome and the other 12% are caused by sporadic, acquired hypermethylation of the promoter of the MLH1 gene, which occurs in tumors with the CpG island methylator phenotype. Colorectal tumors with MSI have distinctive features, including a tendency to arise in the proximal colon, lymphocytic infiltrate, and a poorly differentiated, mucinous or signet ring appearance. They have a slightly better prognosis than colorectal tumors without MSI and do not have the same response to chemotherapeutics. Discovery of MSI in colorectal tumors has increased awareness of the diversity of colorectal cancers and implications for specialized management of patients.
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“however, are commonly identified through separate MSI analysis and/or additional immunohistochemical staining for mismatch repair enzymes in pathology diagnostics2,3,51.”
From Self-supervised learning reveals clinically relevant histomorphological patterns for therapeutic strategies in colon cancer (2025) · cites this paper as [51]
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“MSI-high tumors have been linked to a favorable prognosis2,51, characterized by lower differentiation grade, increased T-cell infiltration, and reduced susceptibility to invasiveness and KRAS mutation51”
From Self-supervised learning reveals clinically relevant histomorphological patterns for therapeutic strategies in colon cancer (2025) · cites this paper as [51]
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“Microsatellite instability (MSI) caused by dysfunctional mismatch repair (dMMR) is detected in approximately 15% of all CRC and in nearly all cases with Lynch syndrome [126].”
From Resistance to anti-EGFR therapies in metastatic colorectal cancer: underlying mechanisms and reversal strategies (2021) · cites this paper as [126]
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Cites
Jemal, A., Bray, F., Ferlay, J., Ward, E., & Forman, D. (2011) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.20107 · Cited by 55,044
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
A genetic model for colorectal tumorigenesis
Fearon, E. R., & Vogelstein, B. (1990) · Cell · doi:10.1016/0092-8674(90)90186-i · Cited by 12,132
Siegel, R., Naishadham, D., & Jemal, A. (2012) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20138 · Cited by 10,679
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
Le, D. T., Uram, J. N., Wang, H., Bartlett, B. R., Kemberling, H., Eyring, A. D., Skora, A. D., Luber, B. S., Azad, N. S., Laheru, D., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1500596 · Cited by 9,377
Comprehensive molecular characterization of human colon and rectal cancer
The Cancer Genome Atlas Network (2012) · Nature · doi:10.1038/nature11252 · Cited by 8,499
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlecnik, B., Lagorce-Pagès, C., Tosolini, M., Camus, M., Berger, A., Wind, P., et al. (2006) · Science · doi:10.1126/science.1129139 · Cited by 6,516
The consensus molecular subtypes of colorectal cancer
Guinney, J., Dienstmann, R., Wang, X., de Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., et al. (2015) · Nature Medicine · doi:10.1038/nm.3967 · Cited by 5,170
Boland, C. R., Thibodeau, S. N., Hamilton, S. R., Sidransky, D., Eshleman, J. R., Burt, R. W., Meltzer, S. J., Rodrı́guez-Bigas, M. A., Fodde, R., Ranzani, G. N., et al. (1998) · PubMed · Cited by 4,087
Self-citationUmar, A., Boland, C. R., Terdiman, J. P., Syngal, S., de la Chapelle, A., Rüschoff, J., Fishel, R. A., Lindor, N. M., Burgart, L. J., Hamelin, R., et al. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh034 · Cited by 3,181
Self-citation
Cited by
Sorted by citations
Items 601–700 of 1,002
Echterdiek, F., Janikovits, J., Staffa, L., Müller, M., Lahrmann, B., Frühschütz, M., Hartog, B., Nelius, N., Benner, A., Tariverdian, M., et al. (2015) · OncoImmunology · doi:10.1080/2162402x.2015.1075692 · Cited by 34
Cancer Treatment in the Genomic Era
Doherty, G. J., Petruzzelli, M., Beddowes, E. J., Ahmad, S. S., Caldas, C., & Gilbertson, R. J. (2019) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-062917-011840 · Cited by 36
Tieng, F. Y. F., Abu, N., Lee, L., & Mutalib, N. A. (2021) · Diagnostics · doi:10.3390/diagnostics11030544 · Cited by 37
Lynch-like Syndrome: Potential Mechanisms and Management
Martínez‐Roca, A., Giner-Calabuig, M., Murcia, Ó., Castillejo, A., Soto, J. L., García‐Heredia, A., & Jover, R. (2022) · Cancers · doi:10.3390/cancers14051115 · Cited by 35
Recent Advances in the Study of Extracellular Vesicles in Colorectal Cancer
Glass, S. E., & Coffey, R. J. (2022) · Gastroenterology · doi:10.1053/j.gastro.2022.06.039 · Cited by 34
Peng, J. M., Li, P., Li, Y., Quan, J., Yao, Y., Duan, J., Liu, X., Li, H., Yuan, D., & Wang, X. (2023) · Scientific Reports · doi:10.1038/s41598-023-43982-2 · Cited by 36
Molecular Complexity of Colorectal Cancer: Pathways, Biomarkers, and Therapeutic Strategies
Yang, Z., Wang, X., Zhou, H., Jiang, M., Wang, J., & Sui, B. (2024) · Cancer Management and Research · doi:10.2147/cmar.s481656 · Cited by 38
Inflammation-Driven Genomic Instability: A Pathway to Cancer Development and Therapy Resistance
Rembiałkowska, N., Kocik, Z., Kłosińska, A., Kübler, M., Pałkiewicz, A., Rozmus, W., Sędzik, M., Wojciechowska, H., & Gajewska-Naryniecka, A. (2025) · Pharmaceuticals · doi:10.3390/ph18091406 · Cited by 42
Brim, H., Lee, E. B., Abu-Asab, M. S., Chaouchi, M., Razjouyan, H., Namin, H. H., Goel, A., Schäffer, A. A., & Ashktorab, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040392 · Cited by 33
Self-citationJu, Y., Kwag, S.-J., Park, H. J., Jung, E., Jeong, C., Jeong, S., Lee, Y., Choi, S.-K., Kang, K. R., Hah, Y., et al. (2014) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24966 · Cited by 33
Characterizing the Prevalence of Chromosome Instability in Interval Colorectal Cancer
Cisyk, A. L., Penner-Goeke, S., Lichtensztejn, Z., Nugent, Z. J., Wightman, R., Singh, H., & McManus, K. J. (2015) · Neoplasia · doi:10.1016/j.neo.2015.02.001 · Cited by 35
Markow, M., Chen, W., & Frankel, W. L. (2017) · Surgical pathology clinics · doi:10.1016/j.path.2017.07.012 · Cited by 33
Climent, M., Ryan, É. J., Stakelum, Á., Khaw, Y. L., Creavin, B., Lloyd, A., Alhassan, D., Mohan, H. M., Kennelly, R. P., Sheahan, K. D., et al. (2019) · International Journal of Colorectal Disease · doi:10.1007/s00384-019-03274-6 · Cited by 33
Diet, Microbiota, and Colorectal Cancer
Grazioso, T. P., Brandt, M., & Djouder, N. (2019) · iScience · doi:10.1016/j.isci.2019.10.011 · Cited by 37
Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer
Wang, S., Jiang, B., Deng, Y., Huang, S.-L., Fang, M., & Wang, Y. (2019) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v11.i11.1065 · Cited by 34
Vos, J. R., Fakkert, I. E., Spruijt, L., Willems, R. W., Langenveld, S., Mensenkamp, A. R., Leter, E. M., Nagtegaal, I. D., Ligtenberg, M. J. L., Hoogerbrugge, N., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.33117 · Cited by 33
Recine, F., Vita, A. D., Fausti, V., Pieri, F., Bongiovanni, A., Franchini, E., Casadei, R., Falasconi, M. C., Oboldi, D., Matteucci, F., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2021.740676 · Cited by 32
A synopsis of modern - day colorectal cancer: Where we stand
Ranasinghe, R., Mathai, M. L., & Zulli, A. (2022) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2022.188699 · Cited by 35
Hao, S., Tong, J., Jha, A., Risnik, D., Lizardo, D. Y., Lu, X. Y., Goel, A., Opresko, P. L., Yu, J., & Zhang, L. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2211775119 · Cited by 32
Self-citationThe Controversial Role of Intestinal Mast Cells in Colon Cancer
Molfetta, R., & Paolini, R. (2023) · Cells · doi:10.3390/cells12030459 · Cited by 36
Woerner, S. M., Tosti, E., Yuan, Y. P., Kloor, M., Peer Bork, B., Edelmann, W., & Gebert, J. F. (2014) · Molecular Carcinogenesis · doi:10.1002/mc.22213 · Cited by 33
Kim, J. H., Kim, K.-J., Rhee, Y.-Y., Oh, S., Cho, N., Lee, H. S., & Kang, G. H. (2013) · Modern Pathology · doi:10.1038/modpathol.2013.160 · Cited by 38
Genomic Instability and Radiation Risk in Molecular Pathways to Colon Cancer
Kaiser, J. C., Meckbach, R., & Jacob, P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111024 · Cited by 33
Stoffel, E. M., & Chittenden, A. B. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.09.018 · Cited by 33
Karagiannis, G. S., Pavlou, M. P., Saraon, P., Musrap, N., Xie, A., Batruch, I., Prassas, I., Dimitromanolakis, A., Petraki, C. D., & Diamandis, E. P. (2014) · Journal of Proteomics · doi:10.1016/j.jprot.2014.03.018 · Cited by 31
Influence of Patient Preferences on the Cost-Effectiveness of Screening for Lynch Syndrome
Wang, G., Kuppermann, M., Kim, B. B., Phillips, K. A., & Ladabaum, U. (2012) · Journal of Oncology Practice · doi:10.1200/jop.2011.000535 · Cited by 33
Kortüm, B., Campregher, C., Lang, M., Khare, V., Pinter, M., Evstatiev, R., Schmid, G., Mittlböck, M., Scharl, T., Kucherlapati, M. H., et al. (2014) · Gut · doi:10.1136/gutjnl-2014-307663 · Cited by 33
Granata, V., Fusco, R., Muzio, F. D., Brunese, M. C., Setola, S. V., Ottaiano, A., Cardone, C., Avallone, A., Patrone, R., Pradella, S., et al. (2023) · La radiologia medica · doi:10.1007/s11547-023-01710-w · Cited by 32
Incorvaia, L., Russo, T. D. B., Gristina, V., Perez, A., Brando, C., Mujacic, C., Giovanni, E. D., Bono, M., Contino, S., Bannera, C. F., et al. (2024) · npj Precision Oncology · doi:10.1038/s41698-024-00672-0 · Cited by 36
Mizutani, T., Boretto, M., Lim, S., Drost, J., González, D. M., Oka, R., Geurts, M. H., Begthel, H., Korving, J., van Es, J. H., et al. (2024) · Nature Cancer · doi:10.1038/s43018-024-00841-x · Cited by 37
An Integrative CGH, MSI and Candidate Genes Methylation Analysis of Colorectal Tumors
Brim, H., Abu-Asab, M. S., Nouraie, M. S., Salazar, J., DeLeo, J., Razjouyan, H., Mokarram, P., Schäffer, A. A., Naghibalhossaini, F., & Ashktorab, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0082185 · Cited by 32
Väyrynen, S. A., Sirniö, P., Väyrynen, J. P., Tuomisto, A., Klintrup, K., Mäkelä, J. T., Ristimaki, A. P., & Mäkinen, M. J. (2014) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-014-1555-0 · Cited by 32
Anticipation in Lynch Syndrome: Where We Are Where We Go
Bozzao, C., Lastella, P., & Stella, A. (2011) · Current Genomics · doi:10.2174/138920211797904070 · Cited by 33
Both hMutSα and hMutSß DNA Mismatch Repair Complexes Participate in 5-Fluorouracil Cytotoxicity
Tajima, A., Iwaizumi, M., Tseng-Rogenski, S. S., Cabrera, B. L., & Carethers, J. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028117 · Cited by 34
Genetic Analysis of Mismatch Repair Genes Alterations in Extramammary Paget Disease
Kang, Z., Xu, F., Zhu, Y., Fu, P., Zhang, Q., Hu, T., Li, X., Zhang, Q., Wu, Z., Zhang, X., et al. (2016) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000709 · Cited by 32
Iorio, F., García‐Alonso, L., Brammeld, J. S., Martincorena, I., Willé, D. R., McDermott, U., & Sáez-Rodríguez, J. (2018) · Scientific Reports · doi:10.1038/s41598-018-25076-6 · Cited by 32
Characterizing Microsatellite Instability and Chromosome Instability in Interval Colorectal Cancers
Cisyk, A. L., Nugent, Z. J., Wightman, R., Singh, H., & McManus, K. J. (2018) · Neoplasia · doi:10.1016/j.neo.2018.07.007 · Cited by 32
Advances in prognostic markers for colorectal cancer
Duan, L., Yang, W., Wang, X., Zhou, W. J., Zhang, Y., Liu, J., Zhang, H., Zhao, Q., Hong, L., & Fan, D. (2019) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2019.1592679 · Cited by 33
Hongo, T., Yamamoto, H., Jiromaru, R., Yasumatsu, R., Kuga, R., Nozaki, Y., Hashimoto, K., Matsuo, M., Wakasaki, T., Tamae, A., et al. (2021) · Modern Pathology · doi:10.1038/s41379-021-00868-w · Cited by 33
Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma
Tomicic, M. T., Dawood, M., & Efferth, T. (2021) · Cancers · doi:10.3390/cancers13164072 · Cited by 33
Feature Re-calibration Based Multiple Instance Learning for Whole Slide Image Classification
Chikontwe, P., Nam, S. J., Go, H., Kim, M., Sung, H. J., & Park, S. H. (2022) · Lecture notes in computer science · doi:10.1007/978-3-031-16434-7_41 · Cited by 32
Reitsam, N. G., Märkl, B., Dintner, S., Waidhauser, J., Vlasenko, D., & Grosser, B. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1019798 · Cited by 35
Greco, L., Rubbino, F., Buono, A. D., & Laghi, L. (2023) · Genes · doi:10.3390/genes14061169 · Cited by 35
Absence of Microsatellite Instability In Soft Tissue Sarcomas
Campanella, N. C., Penna, V., Ribeiro, G., Abrahão‐Machado, L. F., Scapulatempo‐Neto, C., & Reis, R. M. (2015) · Pathobiology · doi:10.1159/000369906 · Cited by 32
Immunohistochemistry of colorectal carcinoma: current practice and evolving applications
Taliano, R., LeGolvan, M. P., & Resnick, M. B. (2012) · Human Pathology · doi:10.1016/j.humpath.2012.04.017 · Cited by 32
Deficient Mismatch Repair and Microsatellite Instability in Solid Tumors
Awosika, J. A., Gulley, J. L., & Pastor, D. M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26094394 · Cited by 38
Gene variants of unknown clinical significance in Lynch syndrome. An introduction for clinicians
Sijmons, R. H., Greenblatt, M. S., & Genuardi, M. (2013) · Familial Cancer · doi:10.1007/s10689-013-9629-8 · Cited by 31
Mladenova, D. N., & Kohonen‐Corish, M. R. J. (2012) · PubMed · Cited by 31
The clinical implications of immunogenomics in colorectal cancer: A path for precision medicine
Riley, J. M., Cross, A. W., Paulos, C. M., Rubinstein, M. P., Wrangle, J. M., & Camp, E. R. (2018) · Cancer · doi:10.1002/cncr.31214 · Cited by 31
Ahmed, K., Zaidi, S. F., Cui, Z., Zhou, D., Saeed, S. A., & Inadera, H. (2019) · Oncology Letters · doi:10.3892/ol.2019.10349 · Cited by 33
Chen, M., Chang, S., Lin, P.-C., Yang, S.-H., Lin, C., Lan, Y., Lin, H., Lin, C., Lai, J., Liang, W.-Y., et al. (2019) · The Oncologist · doi:10.1634/theoncologist.2019-0171 · Cited by 31
Pfuderer, P. L., Ballhausen, A., Seidler, F., Stark, H., Grabe, N., Frayling, I. M., Ager, A., Doeberitz, M. V. K., Kloor, M., & Ahadova, A. (2019) · British Journal of Cancer · doi:10.1038/s41416-019-0514-6 · Cited by 31
Satorres, C., García‐Campos, M., & Bustamante, M. (2020) · Gut and Liver · doi:10.5009/gnl19402 · Cited by 31
Combinatorial Immunotherapies for Metastatic Colorectal Cancer
Janssen, E., Subtil, B., Ortiz, F. D. L. J., Verheul, H. M. W., & Tauriello, D. V. F. (2020) · Cancers · doi:10.3390/cancers12071875 · Cited by 31
Emerging Trends for Radio-Immunotherapy in Rectal Cancer
Corrò, C., Dutoit, V., & Koessler, T. (2021) · Cancers · doi:10.3390/cancers13061374 · Cited by 33
Curcumin's prevention of inflammation-driven early gastric cancer and its molecular mechanism
Zhang, W., Cui, N., Ye, J., Yang, B., Sun, Y., & Kuang, H. (2022) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2021.11.003 · Cited by 31
Zhang, Z., Zheng, M., Ding, Q., & Liu, M. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.817965 · Cited by 31
Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan
Lin, C., Lin, J.-K., Chang, S., Chang, Y., Chang, H.-M., Liu, H., Li, L.-H., Chen, Y.-T., Tsai, S., & Chen, W.-S. (2011) · Journal of Biomedical Science · doi:10.1186/1423-0127-18-36 · Cited by 31
Mäki‐Nevala, S., Valo, S., Ristimaki, A. P., Sarhadi, V. K., Knuutila, S., Nyström, M., Renkonen‐Sinisalo, L., Lepistö, A., Mecklin, J., & Peltomäki, P. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.12.018 · Cited by 31
Review article: Lynch Syndrome—a mechanistic and clinical management update
Curtius, K., Gupta, S. N., & Boland, C. R. (2022) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.16826 · Cited by 36
Self-citationPan-cancer Analysis Identifies AIMP2 as a Potential Biomarker for Breast Cancer
Qiu, J., Zhou, T., Wang, D., Hong, W., Qian, D., Meng, X., & Liu, X. (2023) · Current Genomics · doi:10.2174/0113892029255941231014142050 · Cited by 31
DNA repair-dependent immunogenic liabilities in colorectal cancer: opportunities from errors
Amodio, V., Vitiello, P. P., Bardelli, A., & Germano, G. (2024) · British Journal of Cancer · doi:10.1038/s41416-024-02848-8 · Cited by 33
Esposito, A., Agostini, A., Quero, G., Piro, G., Priori, L., Caggiano, A., Scaglione, G., Battaglia, A., Calegari, M. A., Salvatore, L., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07266-5 · Cited by 32
p53 in colorectal cancer: from a master player to a privileged therapy target
Yan, S., Zhan, F., He, Y., Zhu, Y., & Ma, Z. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06566-4 · Cited by 33
Maletzki, C., Schmidt, F., Dirks, W. G., Schmitt, M. W., & Linnebacher, M. (2013) · European Journal of Cancer · doi:10.1016/j.ejca.2013.02.035 · Cited by 30
Immunotherapy in colorectal cancer
Agarwal, P., Le, D. T., & Boland, P. M. (2021) · Advances in cancer research · doi:10.1016/bs.acr.2021.03.002 · Cited by 31
Wang, T., Stadler, Z. K., Zhang, L., Weiser, M. R., Baştürk, O., Hechtman, J. F., Vakiani, E., Saltz, L. B., Klimstra, D. S., & Shia, J. (2017) · Familial Cancer · doi:10.1007/s10689-017-0031-9 · Cited by 30
Liu, S., Yang, Y., Jiang, C., Quan, Q., Xie, Q., Wang, X., He, W., Rong, Y., Chen, P., Yang, Q., et al. (2018) · Journal of Translational Medicine · doi:10.1186/s12967-018-1570-z · Cited by 30
KCNMA1 Expression Is Downregulated in Colorectal Cancer via Epigenetic Mechanisms
Basile, M. S., Fagone, P., Mangano, K., Mammana, S., Magro, G. G., Salvatorelli, L., Destri, G. L., Greca, G. L., Nicoletti, F., Puleo, S., et al. (2019) · Cancers · doi:10.3390/cancers11020245 · Cited by 30
Sobocińska, J., Kolenda, T., Teresiak, A., Badziąg-Leśniak, N., Kopczyńska, M., Guglas, K., Przybyła, A., Filas, V., Bogajewska-Ryłko, E., Lamperska, K. M., et al. (2020) · Diagnostics · doi:10.3390/diagnostics10100786 · Cited by 30
Almasabi, S., Ahmed, A. U., Boyd, R. L., & Williams, B. R. G. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.638558 · Cited by 31
Li, J., Yang, Z., Xin, B., Hao, Y., Wang, L., Song, S., Xu, J., & Wang, X. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.702055 · Cited by 30
Yu, L., Zhang, M., & Hou, J. (2022) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2022.2088247 · Cited by 32
Targeted Therapy Based on Tumor Genomic Analyses in Metastatic Urachal Carcinoma
Loh, K. P., Mondo, E. L., Hansen, E., Sievert, L., Fung, C., Sahasrabudhe, D. M., & Guancial, E. A. (2016) · Clinical Genitourinary Cancer · doi:10.1016/j.clgc.2016.03.013 · Cited by 30
Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B
Akre, M. K., Starrett, G. J., Quist, J., Temiz, N. A., Carpenter, M. A., Tutt, A. N. J., Grigoriadis, A. E., & Harris, R. S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155391 · Cited by 30
Polycythemia vera and essential thrombocythemia in young patients.
Frezzato, M., Ruggeri, M., Castaman, G., & Rodeghiero, F. (1993) · PubMed · Cited by 30
Snahnicanova, Z., Kasubova, I., Kalman, M., Grendar, M., Mikolajcik, P., Gabonova, E., Laca, L., Caprnda, M., Rodrigo, L., Ciccocioppo, R., et al. (2020) · Clinical and Experimental Medicine · doi:10.1007/s10238-019-00601-7 · Cited by 29
Chen, F., Zhang, Y., Li, X., Gao, J., Ma, H., Wang, X., Li, Y., Li, C., Zhang, Y.-N., Zhang, Y., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-66678-3 · Cited by 29
Quirt, J., Nanji, S. A., Wei, X. S., Flemming, J. A., & Booth, C. M. (2017) · Current Oncology · doi:10.3747/co.24.3410 · Cited by 29
Schneider, N. B., Pastor, T., de Paula, A. E., Achatz, M. I., Ribeiro‐dos‐Santos, Â., Vianna, F. S. L., Rosset, C., Pinheiro, M., Ashton‐Prolla, P., Moreira, M. Â. M., et al. (2018) · Cancer Medicine · doi:10.1002/cam4.1316 · Cited by 29
Yang, Y., Wang, D., Jin, L., Wu, G., Bai, Z., Wang, J., Yao, H., & Zhang, Z. (2018) · Cancer Management and Research · doi:10.2147/cmar.s169649 · Cited by 29
Chu, C.-H., Chang, S., Wang, H.-H., Yang, S.-H., Lai, K., & Lee, T. (2018) · Cancers · doi:10.3390/cancers10100393 · Cited by 29
The Landscape of Tumor-Specific Antigens in Colorectal Cancer
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Gorzo, A., Galoș, D., Volovăț, S. R., Lungulescu, C. V., Burz, C. C., & Sur, D. G. (2022) · Life · doi:10.3390/life12020229 · Cited by 30
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Marino, F. Z., Amato, M., Ronchi, A., Panarese, I., Ferraraccio, F., Vita, F. D., Tirino, G., Martinelli, E., Troiani, T., Facchini, G., et al. (2022) · Cancers · doi:10.3390/cancers14092204 · Cited by 29
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Kim, J. H., Rhee, Y.-Y., Bae, J., Kwon, H.-J., Cho, N., Kim, M. J., & Kang, G. H. (2013) · Modern Pathology · doi:10.1038/modpathol.2012.241 · Cited by 29
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Metadata
- Authors
- Boland, C. R., & Goel, A.
- Affiliations
- Baylor University Medical Center (US)
- Corresponding author
- Boland, C. Richard
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 138
- Issue
- 6
- Pages
- 2073-2087.e3
- ISSN
- 0016-5085 (ISSN-L)
- PMC
- PMC3037515
- OpenAlex
- W2094390470
- Cited by
- 2,456
- References
- 228
- Citations by year
- 2026: 140 · 2025: 201 · 2024: 202 · 2023: 191 · 2022: 257 · 2021: 211 · 2020: 194 · 2019: 160 · 2018: 140 · 2017: 115 · 2016: 112 · 2015: 117 · 2014: 111 · 2013: 100 · 2012: 94
- FWCI
- 11.76
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (R01 CA129286, R01 CA72851)
- National Cancer Institute
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Genetic factors in colorectal cancer
- Health Sciences › Medicine › Oncology › Colorectal Cancer Treatments and Studies
- Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
- Keywords
- microsatellite instability, colorectal cancer, DNA mismatch repair, Lynch syndrome, MLH1 promoter methylation, CpG island methylator phenotype, proximal colon tumors, lymphocyte infiltration, mucinous tumors, signet ring cell carcinoma, prognosis, chemotherapy response
- MeSH terms
- Animals, Cell Transformation, Neoplastic, Colorectal Neoplasms, Hereditary Nonpolyposis, Humans, Mutation, Phenotype, Risk Factors, Colorectal Neoplasms, Gene Expression Regulation, Neoplastic, Treatment Outcome, Genetic Predisposition to Disease, Microsatellite Instability, DNA Mismatch Repair
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