The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.
The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease
Open accessAbstract
Fecal and serologic biomarkers can be used in the diagnosis and management of inflammatory bowel disease (IBD). Fecal markers such as calprotectin and lactoferrin have been studied for their ability to identify patients with IBD, assess disease activity, and predict relapse. Antibodies against Saccharomyces cerevisiae and perinuclear antineutrophil cytoplasmic proteins have been used in diagnosis of IBD, to distinguish Crohn's disease (CD) from ulcerative colitis, and to predict the risk of complications of CD. Tests for c-reactive protein and erythrocyte sedimentation rate have been used to assess inflammatory processes and predict the course of IBD progression. Levels of drug metabolites and antibodies against therapeutic agents might be measured to determine why patients do not respond to therapy and to select alternative treatments. This review addresses the potential for biomarker assays to improve treatment strategies and challenges to their use and development.
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Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease
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Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease
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Laboratory markers in IBD: useful, magic, or unnecessary toys?
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Mucosal Healing Predicts Sustained Clinical Remission in Patients With Early-Stage Crohn's Disease
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Predicting outcome in severe ulcerative colitis.
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Cited by
Dynamics of the human gut microbiome in inflammatory bowel disease
Halfvarson, J., Brislawn, C. J., Lamendella, R., Vázquez-Baeza, Y., Walters, W. A., Bramer, L. M., D'Amato, M., Bonfiglio, F., McDonald, D., Gonzalez, A., et al. (2017) · Nature Microbiology · doi:10.1038/nmicrobiol.2017.4 · Cited by 1,204
Lewis, J. D., Chen, E. Z., Baldassano, R. N., Otley, A. R., Griffiths, A. M., Lee, D., Bittinger, K., Bailey, A., Friedman, E. S., Hoffmann, C., et al. (2015) · Cell Host & Microbe · doi:10.1016/j.chom.2015.09.008 · Cited by 823
Self-citationEvidence-based clinical practice guidelines for inflammatory bowel disease
Matsuoka, K., Kobayashi, T., Ueno, F., Matsui, T., Hirai, F., Inoue, N., Kato, J., Kobayashi, K., Kobayashi, K., Koganei, K., et al. (2018) · Journal of Gastroenterology · doi:10.1007/s00535-018-1439-1 · Cited by 698
Bernardi, M., Moreau, R., Angeli, P., Schnabl, B., & Arroyo, V. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.07.004 · Cited by 632
Chassaing, B., Srinivasan, G., Delgado, M. A., Young, A. N., Gewirtz, A. T., & Vijay-Kumar, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044328 · Cited by 554
Metadata
- Authors
- Lewis, J. D.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2011-05
- Volume
- 140
- Issue
- 6
- Pages
- 1817-1826.e2
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2015747379
- Cited by
- 458
- References
- 106
- FWCI
- 23.20
- Type
- journal article
- Language
- en
- Open access
- green
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