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Cited by 1,162

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference

Open access
Dellon, Evan S., Liacouras, Chris A., Molina-Infante, Javier, Furuta, Glenn T., Spergel, Jonathan M., Zevit, Noam, Spechler, Stuart J., Attwood, Stephen E., Straumann, Alex, Aceves, Seema S., Alexander, Jeffrey A., Atkins, Dan, Arva, Nicoleta C., Blanchard, Carine, Bonis, Peter A., Book, Wendy M., Capocelli, Kelley E., Chehade, Mirna, Cheng, Edaire, Collins, Margaret H., Davis, Carla M., Dias, Jorge A., Di Lorenzo, Carlo, Dohil, Ranjan, Dupont, Christophe, Falk, Gary W., Ferreira, Cristina T., Fox, Adam, Gonsalves, Nirmala P., Gupta, Sandeep K., Katzka, David A., Kinoshita, Yoshikazu, Menard-Katcher, Calies, Kodroff, Ellyn, Metz, David C., Miehlke, Stephan, Muir, Amanda B., Mukkada, Vincent A., Murch, Simon, Nurko, Samuel, Ohtsuka, Yoshikazu, Orel, Rok, Papadopoulou, Alexandra, Peterson, Kathryn A., Philpott, Hamish, Putnam, Philip E., Richter, Joel E., Rosen, Rachel, Rothenberg, Marc E., Schoepfer, Alain, Scott, Melissa M., Shah, Neil, Sheikh, Javed, Souza, Rhonda F., Strobel, Mary J., Talley, Nicholas J., Vaezi, Michael F., Vandenplas, Yvan, Vieira, Mario C., Walker, Marjorie M., Wechsler, Joshua B., Wershil, Barry K., Wen, Ting, Yang, Guang-Yu, Hirano, Ikuo, Bredenoord, Albert J.·2018·Gastroenterology
DOI 10.1053/j.gastro.2018.07.009
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Abstract

Background and Aims: Over the last decade, clinical experiences and research studies raised concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for eosinophilic esophagitis (EoE). We aimed to clarify the use of PPIs in the evaluation and treatment of children and adults with suspected EoE in order to develop updated international consensus criteria for EoE diagnosis. Methods: A consensus conference was convened to address the issue of PPI use for esophageal eosinophilia using a process consistent with standards described in the Appraisal of Guidelines for Research and Evaluation II. Pediatric and adult physicians and researchers from gastroenterology, allergy, and pathology subspecialties representing 14 countries utilized on-line communications, teleconferences, and a face-to-face meeting to review the literature and clinical experiences. Results: Substantial evidence documented that PPIs reduce esophageal eosinophilia in children, adolescents and adults, with several mechanisms potentially explaining the treatment effect. Based on these findings, an updated diagnostic algorithm for EoE was developed, with removal of the PPI trial requirement. Conclusions: EoE should be diagnosed when there are symptoms of esophageal dysfunction and at least 15 eosinophils per high-power field (or ~60 eosinophils per mm2) on esophageal biopsy, and after a comprehensive assessment of non-EoE disorders that could cause or potentially contribute to esophageal eosinophilia. The evidence suggests that PPIs are better classified as a treatment for esophageal eosinophilia that may be due to EoE than as a diagnostic criterion, and we have developed updated consensus criteria for EoE that reflect this change.

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Metadata

Authors
Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., Alexander, J. A., Atkins, D., Arva, N. C., Blanchard, C., Bonis, P. A., Book, W. M., Capocelli, K. E., Chehade, M., Cheng, E., Collins, M. H., Davis, C. M., Dias, J. A., Di Lorenzo, C., Dohil, R., Dupont, C., Falk, G. W., Ferreira, C. T., Fox, A., Gonsalves, N. P., Gupta, S. K., Katzka, D. A., Kinoshita, Y., Menard-Katcher, C., Kodroff, E., Metz, D. C., Miehlke, S., Muir, A. B., Mukkada, V. A., Murch, S., Nurko, S., Ohtsuka, Y., Orel, R., Papadopoulou, A., Peterson, K. A., Philpott, H., Putnam, P. E., Richter, J. E., Rosen, R., Rothenberg, M. E., Schoepfer, A., Scott, M. M., Shah, N., Sheikh, J., Souza, R. F., Strobel, M. J., Talley, N. J., Vaezi, M. F., Vandenplas, Y., Vieira, M. C., Walker, M. M., Wechsler, J. B., Wershil, B. K., Wen, T., Yang, G.-Y., Hirano, I., & Bredenoord, A. J.
Venue
Gastroenterology
Publisher
Elsevier BV
Published
2018-10
Volume
155
Issue
4
Pages
1022-1033.e10
ISSN
0016-5085 (ISSN-L)
DOI
10.1053/j.gastro.2018.07.009
OpenAlex
W2883311417
Cited by
1,162
References
94
FWCI
97.56
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. https://app.cochat.ai/papers/10.1053/j.gastro.2018.07.009
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Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., Alexander, J. A., Atkins, D., Arva, N. C., Blanchard, C., Bonis, P. A., Book, W. M., Capocelli, K. E., Chehade, M., Cheng, E., . . . Bredenoord, A. J. (2018). Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. https://doi.org/10.1053/j.gastro.2018.07.009

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.