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ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus

Open access
Shaheen, Nicholas J, Falk, Gary W, Iyer, Prasad G, Gerson, Lauren B·2016·American Journal of Gastroenterology

Abstract

Barrett's esophagus (BE) is among the most common conditions encountered by the gastroenterologist. In this document, the American College of Gastroenterology updates its guidance for the best practices in caring for these patients. These guidelines continue to endorse screening of high-risk patients for BE; however, routine screening is limited to men with reflux symptoms and multiple other risk factors. Acknowledging recent data on the low risk of malignant progression in patients with nondysplastic BE, endoscopic surveillance intervals are attenuated in this population; patients with nondysplastic BE should undergo endoscopic surveillance no more frequently than every 3-5 years. Neither routine use of biomarker panels nor advanced endoscopic imaging techniques (beyond high-definition endoscopy) is recommended at this time. Endoscopic ablative therapy is recommended for patients with BE and high-grade dysplasia, as well as T1a esophageal adenocarcinoma. Based on recent level 1 evidence, endoscopic ablative therapy is also recommended for patients with BE and low-grade dysplasia, although endoscopic surveillance continues to be an acceptable alternative. Given the relatively common recurrence of BE after ablation, we suggest postablation endoscopic surveillance intervals. Although many of the recommendations provided are based on weak evidence or expert opinion, this document provides a pragmatic framework for the care of the patient with BE.

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Metadata

Authors
Shaheen, N. J., Falk, G. W., Iyer, P. G., & Gerson, L. B.
Venue
American Journal of Gastroenterology
Published
2016-01
Volume
111
Issue
1
Pages
30-50
ISSN
0002-9270 (ISSN-L)
OpenAlex
W2187093113
Cited by
1,501
References
2
FWCI
124.22
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus. https://app.cochat.ai/papers/10.1038/ajg.2015.322
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Shaheen, N. J., Falk, G. W., Iyer, P. G., & Gerson, L. B. (2016). ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus. American Journal of Gastroenterology. https://doi.org/10.1038/ajg.2015.322

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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