The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
A Prospective, Randomized Trial of Butyl Cyanoacrylate Injection Versus Band Ligation in the Management of Bleeding Gastric Varices
Abstract
Gastric variceal bleeding is a catastrophic event. Both cyanoacrylate injection and banding ligation have been proven to be effective in the management of bleeding gastric varices. This study was performed to compare the efficacy and complications of both the modalities. Cirrhotic patients with a history of gastric variceal bleeding were randomized to 2 groups. The group receiving endoscopic obturation (group A) comprised 31 patients and the group receiving band ligation (group B) comprised 29 patients. Butyl cyanoacrylate and pneumatic–driven ligator were applied, respectively. Treatment was repeated regularly until obliteration of gastric varices. Active bleeding occurred in 15 patients in group A and 11 patients in group B. Initial hemostatic rate (defined as no bleeding for 72 hours after treatment) was 87% in group A and 45% in group B (P = .03). The sessions required to achieve variceal obliteration and obliteration rates were similar in both the groups. However, rebleeding rates were significantly higher in group B (54%) than group A (31%) (P = .0005). Treatment–induced ulcer bleeding occurred in 2 patients (7%) in group A and 8 patients (28%) in group B (P = .03). The amount of blood transfusions required were also higher in group B than group A (4.2 ± 1.3 vs. 2.6 ± 0.9 units, respectively) (P < .01). Nine patients of group A and 14 patients of group B died (P = .05). In conclusion, endoscopic obturation using cyanoacrylate proved more effective and safer than band ligation in the management of bleeding gastric varices.
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Endoscopic Sclerotherapy as Compared with Endoscopic Ligation for Bleeding Esophageal Varices
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Lee, N., Choi, S. H., & Hyeon, T. (2013) · Advanced Materials · doi:10.1002/adma.201300081 · Cited by 657
Kaplan, D. E., Ripoll, C., Thiele, M., Fortune, B. E., Simonetto, D. A., Garcia-Tsao, G., & Bosch, J. (2024) · Hepatology · doi:10.1097/hep.0000000000000647 · Cited by 486
Advanced bioactive nanomaterials for biomedical applications
Zhao, Y., Zhang, Z., Pan, Z., & Liu, Y. (2021) · Exploration · doi:10.1002/exp.20210089 · Cited by 357
Acute-on-chronic liver failure: Objective admission and support criteria in the intensive care unit
Dong, V., & Karvellas, C. J. (2019) · JHEP Reports · doi:10.1016/j.jhepr.2019.02.005 · Cited by 38
Metadata
- Authors
- Lo, G.-H., Lai, K.-H., Cheng, J.-S., Chen, M.-H., & Chiang, H.-T.
- Venue
- Hepatology
- Published
- 2001-05
- Volume
- 33
- Issue
- 5
- Pages
- 1060-1064
- ISSN
- 0270-9139 (ISSN-L)
- OpenAlex
- W2029662098
- Cited by
- 485
- References
- 17
- FWCI
- 8.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lo, G.-H., Lai, K.-H., Cheng, J.-S., Chen, M.-H., & Chiang, H.-T. (2001). A Prospective, Randomized Trial of Butyl Cyanoacrylate Injection Versus Band Ligation in the Management of Bleeding Gastric Varices. Hepatology. https://doi.org/10.1053/jhep.2001.24116
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