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Cited by 205

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Influence of tumor characteristics on the outcome of liver transplantation among patients with liver cirrhosis and hepatocellular carcinoma

Open access
Herrero, Ignacio J., Sangro, Bruno, Quiroga, Jorge, Pardo, Fernando, Herraiz, Maite, Cienfuegos, Javier A., Prieto, Jesus·2001·Liver Transplantation

Abstract

Hepatocellular carcinoma (HCC) may recur after liver transplantation (LT), mainly in patients with multinodular and large tumors. However, factors predictive of outcome after LT in patients with small tumors remain ill defined. We investigated which factors were related to mortality or tumor recurrence among 47 liver transplant recipients with liver cirrhosis and HCC and compared them with 107 patients with liver cirrhosis without tumor who underwent LT in the same period. Patients with HCC were older (P < .001), more frequently had cirrhosis of a viral origin (P < .001), and had lower Child-Pugh scores (P < .001) than patients without tumor. Survival of patients with and without tumor was not significantly different (P = .20). Among patients with HCC, those with lower recurrence-free survival rates had liver cirrhosis of a viral origin, vascular invasion, bilobar disease, and tumor-node-metastasis (TNM) stage IV. At multivariate analysis, the only factor associated with mortality or recurrence was TNM stage IV (P = .02). Our results suggest that in patients with HCC and TNM stage IV, LT might be contraindicated.

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Metadata

Authors
Herrero, I. J., Sangro, B., Quiroga, J., Pardo, F., Herraiz, M., Cienfuegos, J. A., & Prieto, J.
Venue
Liver Transplantation
Published
2001-07
Volume
7
Issue
7
Pages
631-636
ISSN
1527-6465 (ISSN-L)
OpenAlex
W2118865824
Cited by
205
References
1
FWCI
4.26
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Influence of tumor characteristics on the outcome of liver transplantation among patients with liver cirrhosis and hepatocellular carcinoma. https://app.cochat.ai/papers/10.1053/jlts.2001.25458
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Herrero, I. J., Sangro, B., Quiroga, J., Pardo, F., Herraiz, M., Cienfuegos, J. A., & Prieto, J. (2001). Influence of tumor characteristics on the outcome of liver transplantation among patients with liver cirrhosis and hepatocellular carcinoma. Liver Transplantation. https://doi.org/10.1053/jlts.2001.25458

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