Cited by 195Sleep and related disordersMenopause: Health Impacts and TreatmentsObstructive Sleep Apnea Research

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Evaluation and Management of Sleep Disturbance during the Menopause Transition

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Joffe, Hadine, Massler, Anda, Sharkey, Katherine·2010·Seminars in Reproductive Medicine

DOI 10.1055/s-0030-1262900PMC PMC3736837

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Abstract

Sleep disturbances in midlife women are common and have been associated with the menopause transition itself, symptoms of hot flashes, anxiety and depressive disorders, aging, primary sleep disorders (i.e., obstructive sleep apnea, periodic limb movement disorder), comorbid medical conditions and medications, as well as with psychosocial and behavioral factors. Because there are several common sources of sleep problems in midlife women, the cause of an individual woman's sleep disturbance may be multifactorial. Effective behavioral and pharmacological therapies are available to treat sleep disturbances of different etiologies. This review provides an overview of different types of sleep disturbance occurring in midlife women and presents data supporting the use of hormone therapy, hypnotic agents, and behavioral strategies to treat sleep problems in this population. The review aims to equip clinicians evaluating menopause-age women with the knowledge and evaluation tools to diagnose, engage sleep experts where appropriate, and treat sleep disturbance in this population. Sleep disorders in midlife women should be treated because substantial improvements in quality of life and health outcomes are achievable.

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Authors: Joffe, H., Massler, A., & Sharkey, K.
Affiliations: Harvard University (US)
Brown University (US)
ORCID: Joffe, Hadine
Sharkey, Katherine
Venue: Seminars in Reproductive Medicine
Publisher: Georg Thieme Verlag KG
Published: 2010-09
Volume: 28
Issue: 05
Pages: 404-421
ISSN: 1526-4564 (ISSN-L)
1526-8004
DOI: 10.1055/s-0030-1262900
PMC: PMC3736837
OpenAlex: W2030417265
Cited by: 195
References: 143
Citations by year: 2026: 13 · 2025: 9 · 2024: 11 · 2023: 14 · 2022: 11 · 2021: 17 · 2020: 14 · 2019: 15 · 2018: 13 · 2017: 13 · 2016: 16 · 2015: 16 · 2014: 13 · 2013: 11 · 2012: 5
FWCI: 8.37
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Seminars in Reproductive Medicine (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Institute of Mental Health (R01MH082922)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
Keywords: sleep disorders, perimenopause, middle-aged women, hot flashes, hormone therapy, hypnotics, obstructive sleep apnea, periodic limb movement disorder, anxiety and depression, primary sleep disorders, quality of life
MeSH terms: Behavior Therapy, Female, Humans, Sleep Initiation and Maintenance Disorders, Menopause, Middle Aged, Terminology as Topic

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Evaluation and Management of Sleep Disturbance during the Menopause Transition

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