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Evaluation and Management of Sleep Disturbance during the Menopause Transition
Open accessAbstract
Sleep disturbances in midlife women are common and have been associated with the menopause transition itself, symptoms of hot flashes, anxiety and depressive disorders, aging, primary sleep disorders (i.e., obstructive sleep apnea, periodic limb movement disorder), comorbid medical conditions and medications, as well as with psychosocial and behavioral factors. Because there are several common sources of sleep problems in midlife women, the cause of an individual woman's sleep disturbance may be multifactorial. Effective behavioral and pharmacological therapies are available to treat sleep disturbances of different etiologies. This review provides an overview of different types of sleep disturbance occurring in midlife women and presents data supporting the use of hormone therapy, hypnotic agents, and behavioral strategies to treat sleep problems in this population. The review aims to equip clinicians evaluating menopause-age women with the knowledge and evaluation tools to diagnose, engage sleep experts where appropriate, and treat sleep disturbance in this population. Sleep disorders in midlife women should be treated because substantial improvements in quality of life and health outcomes are achievable.
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“Among 11 studies that examined the effects of HT on objective measures of sleep, few found significant benefits [126].”
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Metadata
- Authors
- Joffe, H., Massler, A., & Sharkey, K.
- Affiliations
- Harvard University (US)
- Brown University (US)
- Venue
- Seminars in Reproductive Medicine
- Publisher
- Georg Thieme Verlag KG
- Published
- 2010-09
- Volume
- 28
- Issue
- 05
- Pages
- 404-421
- ISSN
- 1526-4564 (ISSN-L)
- 1526-8004
- PMC
- PMC3736837
- OpenAlex
- W2030417265
- Cited by
- 195
- References
- 143
- Citations by year
- 2026: 13 · 2025: 9 · 2024: 11 · 2023: 14 · 2022: 11 · 2021: 17 · 2020: 14 · 2019: 15 · 2018: 13 · 2017: 13 · 2016: 16 · 2015: 16 · 2014: 13 · 2013: 11 · 2012: 5
- FWCI
- 8.37
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Seminars in Reproductive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R01MH082922)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Keywords
- sleep disorders, perimenopause, middle-aged women, hot flashes, hormone therapy, hypnotics, obstructive sleep apnea, periodic limb movement disorder, anxiety and depression, primary sleep disorders, quality of life
- MeSH terms
- Behavior Therapy, Female, Humans, Sleep Initiation and Maintenance Disorders, Menopause, Middle Aged, Terminology as Topic
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