Effect of a sustained program of resistance training on the acute growth hormone response to resistance exercise in older adults
Abstract
We have previously shown that an episode of resistance exercise provokes an acute rise in circulating growth hormone (GH), and that this rise is severely blunted in older men and women. To determine whether this impairment simply reflects the decreased physical fitness of older people, we studied the effects of long-term resistance training on circulating levels of GH and insulin-like growth factor I (IGF-I) and on the acute GH response to exercise in 5 men and 9 women, aged 69.6 +/- 1.1 yrs (SEM). Subjects were randomly assigned to either an exercise program, consisting of 12 weight-lifting exercises (3 sets of 8 repetitions, 3 times each week) or to a control group. After testing maximum baseline strength by the 1 RM method, subjects returned to the laboratory for assessment of basal GH and IGF-I levels and the GH response to exercise. Venous blood was drawn at baseline, after each of 12 exercises (3 sets of 8 repetitions at 85% 1 RM), and every 2 minutes into the first 10 minutes of recovery. The exercise circuit with blood sampling was repeated at 15, 30 and 52 weeks for both groups. Basal GH and IGF-I values did not change in either group throughout the training period nor did the GH secretory response to exercise. Three exercisers had a peak GH concentration greater than 8 micrograms/l after 30 weeks of training, although only one of these showed a significant increase (29 micrograms/l) after 52 weeks.(ABSTRACT TRUNCATED AT 250 WORDS)
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Resistance exercise training does not change the acute effect of exercise on GH release in young or old subjects.
“but RET does not change the acute effect of exercise on GH release in young283 or old281 subjects.”
From Hormonal and Metabolic Changes of Aging and the Influence of Lifestyle Modifications (2021) · cites this paper as [281]
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- Authors
- Pyka, G., Taaffe, D., & Marcus, R.
- Affiliations
- VA Palo Alto Health Care System (US)
- Veterans Health Administration (US)
- ORCID
- Venue
- Hormone and Metabolic Research
- Publisher
- Georg Thieme Verlag KG
- Published
- 1994-07
- Volume
- 26
- Issue
- 07
- Pages
- 330-333
- ISSN
- 0018-5043 (ISSN-L)
- 1439-4286
- OpenAlex
- W2079194152
- Cited by
- 73
- References
- 0
- Citations by year
- 2025: 2 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 2 · 2012: 1
- FWCI
- 1.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Hormone and Metabolic Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Veterans Affairs
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Keywords
- resistance training, growth hormone, older adults, insulin-like growth factor I, weightlifting, aging, physical fitness, exercise training
- MeSH terms
- Aged, Female, Humans, Insulin-Like Growth Factor I, Male, Middle Aged, Muscles, Physical Fitness, Growth Hormone, Weight Lifting, Exercise
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