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Studies on the Constituents of Artemisia annua Part II*
Open accessAbstract
The present paper is a continuation of our study on the Chinese traditional herb Artemisia annua L. [1-5], describing several additional constituents: quinghaosu IV and V (V, VII), quinghao acid (VIII) [6], chrysosplenol (VIa) [7] and a paraffinic alcohol; V, VII and VIII are compounds with unreported structures. Key Word Index Artemisia annua L. - Compositae - Qinghaosu - Qinghaosu I-V - Qinghao acid - Flavones - Alkanol - Scopoletin - Essential oil
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“and were amongst the first sesquiterpenes to be reported from A. annua.”
From The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao) (2010) · cites this paper as [147]
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“Artemisinic acid (473) [105,147,148], arteannuin B (462) [105,147,149] and artemisinin (495) [105,147,150] are the most abundant representatives of this class of natural products”
From The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao) (2010) · cites this paper as [147]
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Research works printed but not linked: 10
- I) Cooperative research group on the structure of qinghaosu: Kexue Toiigbao 22, 142 (1977).
- Liu,J.M.,M.Y.Ni,J.F.Fan, Y. Y. Tu, Z. H. Wu. Y. L. Wu and W. S. Zhou: Acta Chimica Sinica 37, 129 (1979).
- Journal reporter: J. New Med. /,10(1979).
- Cooperative research group on qinghaosu: Yaoxue Tongbao /4,49 (1979).
- Tu, Y. Y., M. Y. Ni. Y. R. Zhong. L. N. Li, S. L. Cui, M. 0. Zhang, X. Z. Wang and X. T. Liang: Acta Pharm. Sinica /6, 366 (1981).
- Ghisalberti, F. L., P. R. Jeffe- ries and C. I. Stacey: Aust. J. Chem. 20(5), 1049 (1967).
- Jeremic, D., A. Jokic, A. Beh- bud and M. Stefanovic: Tetrahe- dron Letters 32,3039(1973).
- Vlahav, R., M. Hoiub and V. Herout: Coil. Czech. Chem. Comm. 32, 822 (1967).
- Liang. X. T.: NMR, Analysis and Appiications of High Resoiu- tion Proton Spectra (in Chinese), p. 268, Science Press (1976).
- Ryhage, R. and E. Stenha- gen: J. Lipid Research 1, 361 (1960).
Cited by
Sorted by citations
The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine
Tu, Y. (2011) · Nature Medicine · doi:10.1038/nm.2471 · Cited by 1,397
“However, the prevailing environment in China at the time restrained the publication of any papers concerning qinghaosu, with the exception of several published in Chines”
BackgroundThe Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
Brown, G. D. (2010) · Molecules · doi:10.3390/molecules15117603 · Cited by 363
Current status of artemisinin and its derivatives as antimalarial drugs
Dhingra, V., Rao, K. V., & Narasu, M. L. (1999) · Life Sciences · doi:10.1016/s0024-3205(99)00356-2 · Cited by 244
In vivo transformations of dihydroartemisinic acid in Artemisia annua plants
Brown, G. D., & Sy, L.-K. (2004) · Tetrahedron · doi:10.1016/j.tet.2003.11.070 · Cited by 183
Artemisinin, a Constituent of Annual Wormwood (Artemisia annua), is a Selective Phytotoxin
Duke, S. O., Vaughn, K. C., Croom, E. M., & ElSohly, H. N. (1987) · Weed Science · doi:10.1017/s0043174500060458 · Cited by 186
Metadata
- Authors
- You-you, T., Mu-yun, N., Yu-rong, Z., Lan-na, L., Shu-lian, C., Mu-qun, Z., Xiu-zhen, W., Zheng, J., & Xiao-tian, L.
- Affiliations
- Institute of Chinese Materia Medica (CN)
- ORCID
- Zheng, Ji
- Venue
- Planta Medica
- Publisher
- Georg Thieme Verlag KG
- Published
- 1982-03
- Volume
- 44
- Issue
- 03
- Pages
- 143-145
- ISSN
- 0032-0943 (ISSN-L)
- 1439-0221
- OpenAlex
- W1971899040
- Cited by
- 125
- References
- 0
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 9 · 2020: 9 · 2019: 4 · 2018: 6 · 2017: 4 · 2016: 10 · 2015: 2 · 2014: 4 · 2013: 4 · 2012: 1
- FWCI
- 0.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Planta Medica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Sesquiterpenes and Asteraceae Studies
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant chemical constituents analysis
- Keywords
- Artemisia annua, scopoletin, flavones, essential oils, natural compounds, traditional Chinese medicine
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