The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Assessment of Prognosis of Cirrhosis
Abstract
Once patients with cirrhosis experience decompensation, early mortality risk increases sharply. Liver transplantation has transformed the prognosis of decompensated cirrhosis. Child-Pugh score has been the reference for many years for assessing the prognosis of cirrhosis. However, Child-Pugh score has important limitations among which is subjective interpretation of some of its variables, making it difficult to categorize patients according to their own disease severity. The model for end-stage liver disease (MELD) score, which was originally designed for assessing the prognosis of cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt (TIPS), is a continuous score relying on three objective variables. Along with TIPS, MELD score proved to be a robust marker of early mortality across a wide spectrum of causes of cirrhosis, even though 10 to 20% of patients are still misclassified. MELD is especially useful for prioritizing candidates for transplantation according to a "sickest first" policy. However, MELD is not a universal prognostic marker of cirrhosis and several MELD exceptions require more specific approaches.
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Citations
Cites
Prognosis in primary biliary cirrhosis: Model for decision making
Dickson, R. E., Grambsch, P. M., Fleming, T. R., Fisher, L. D., & Langworthy, A. (1989) · Hepatology · doi:10.1002/hep.1840100102 · Cited by 816 · cited 1×
“PBC PBC is one of the causes of cirrhosis for which specific prognostic scores were first proposed.(61,62) The aim of scoring was to determine the optimal timing for transplantation.”
Background
Cited by
Telomerase gene mutations are associated with cirrhosis formation
Hartmann, D., Srivastava, U., Thaler, M., Kleinhans, K. N., N'Kontchou, G., Scheffold, A., Bauer, K., Kratzer, R. F., Kloos, N., Katz, S.-F., et al. (2011) · Hepatology · doi:10.1002/hep.24217 · Cited by 173
The MELD score in patients awaiting liver transplant: Strengths and weaknesses
Bernardi, M., Gitto, S., & Biselli, M. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2010.11.008 · Cited by 174
Inorganics in sugarcane bagasse and straw and their impacts for bioenergy and biorefining: A review
Negrão, D. R., Grandis, A., Buckeridge, M. S., Rocha, G. J. M., Leal, M. R. L. V., & Driemeier, C. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111268 · Cited by 86
IGF-I and IGFBP-3 serum levels in patients hospitalized for complications of liver cirrhosis
Ronsoni, M. F., Lazzarotto, C., Fayad, L., Silva, M. C., Nogueira, C. L., Bazzo, M. L., Narciso-Schiavon, J. L., Dantas-Corrêa, E. B., & Schiavon, L. D. L. (2013) · Annals of Hepatology · doi:10.1016/s1665-2681(19)31009-9 · Cited by 20
Metadata
- Authors
- Durand, F., & Valla, D.
- Venue
- Seminars in Liver Disease
- Publisher
- Georg Thieme Verlag KG
- Published
- 2008-02
- Volume
- 28
- Issue
- 1
- Pages
- 110-122
- ISSN
- 0272-8087 (ISSN-L)
- 1098-8971
- OpenAlex
- W2041820052
- Cited by
- 410
- References
- 1
- FWCI
- 10.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Durand, F., & Valla, D. (2008). Assessment of Prognosis of Cirrhosis. Seminars in Liver Disease. https://doi.org/10.1055/s-2008-1040325
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
