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Fulminant and Subfulminant Liver Failure: Definitions and Causes
Abstract
Fulminant or subfulminant liver failure, complicated by encephalopathy and in many cases by death is seen to be a syndrome that may result from numerous causes. Although viral hepatitis, drug-induced hepatitis, and hepatitis due to various types of poisonings, in decreasing frequency, account for 90% of all cases, a variety of miscellaneous conditions account for the remainder. Consideration of the possibility of these less common etiologies by the clinician is of considerable importance, since some, including massive malignant involvement (such as leukemia) or acute fulminant Wilson's disease, may respond to specific treatment measures. Thus, unless hepatic transplantation proves to be applicable in FHF of many etiologic diagnosis may continue to have important therapeutic indications in at least some cases with this syndrome.
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Ostapowicz, G., Fontana, R. J., Schiødt, F. V., Larson, A., Davern, T. J., Han, S. H. B., McCashland, T. M., Shakil, A. O., Hay, J. E., Hynan, L., et al. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-12-200212170-00007 · Cited by 2,227
Sarin, S. K., Kedarisetty, C. K., Abbas, Z., Amarapurkar, D., Bihari, C., Chan, A. C. Y., Chawla, Y. K., Dokmeci, A. K., Garg, H., Ghazinyan, H., et al. (2014) · Hepatology International · doi:10.1007/s12072-014-9580-2 · Cited by 1,481
Bernal, W., & Wendon, J. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1208937 · Cited by 1,169
ESPEN guideline on clinical nutrition in liver disease
Plauth, M., Bernal, W., Dasarathy, S., Merli, M., Plank, L. D., Schütz, T., & Bischoff, S. C. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2018.12.022 · Cited by 674
Larsen, F. S., Schmidt, L. E., Bernsmeier, C., Rasmussen, A., Isoniemi, H., Patel, V. C., Triantafyllou, E., Bernal, W., Auzinger, G., Shawcross, D., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2015.08.018 · Cited by 659
Metadata
- Authors
- Bernuau, J., Rueff, B., & Benhamou, J.-P.
- Venue
- Seminars in Liver Disease
- Publisher
- Georg Thieme Verlag KG
- Published
- 1986-05
- Volume
- 6
- Issue
- 02
- Pages
- 97-106
- ISSN
- 0272-8087 (ISSN-L)
- 1098-8971
- OpenAlex
- W2038360824
- Cited by
- 632
- References
- 0
- FWCI
- 9.90
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Fulminant and Subfulminant Liver Failure: Definitions and Causes. https://app.cochat.ai/papers/10.1055/s-2008-1040593
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- Bernuau, J., Rueff, B., & Benhamou, J.-P. (1986). Fulminant and Subfulminant Liver Failure: Definitions and Causes. Seminars in Liver Disease. https://doi.org/10.1055/s-2008-1040593
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
