Gestational Diabetes: Unsuspected, Asymptomatic Diabetes in Pregnancy
Abstract
ALTHOUGH much has been written about the harmful effects on pregnancy of diabetes mellitus and its earlier stages,1 2 3 variously termed suspected diabetes, latent diabetes and prediagnosis diabetes or prediabetes, there is disagreement about the diagnostic criteria. The answer to this situation is complicated by problems of definition, confused by spontaneous remissions and hindered by lack of well documented longitudinal studies with the available diagnostic tools, which are, unfortunately, far from ideal. As a result claims are made for the predictive value of minor deviations in glucose tolerance whether produced artificially by glucogenic steroids4 or naturally by conditions with diabetogenic effects . . .
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In 1961 the incidence of gestational diabetes mellitus was estimated to be less than 1%, and it increased from 0.3% in 1979-1980 to 5.8% in 2008-2010.
“While in 1961 the incidence of GDM was estimated to be less than 1% [49,50], it increased from 0.3% in 1979–1980 to 5.8% in 2008–2010 [51].”
From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [49]
Maternal obesity is a well-known independent risk factor for gestational diabetes mellitus.
“Maternal obesity is a well-known, independent risk factor for GDM.”
From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [49]
Cited by
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McIntyre, H. D., Catalano, P., Zhang, C., Desoye, G., Mathiesen, E. R., & Damm, P. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0098-8 · Cited by 1,850 · see citing works
Gestational Diabetes: Overview with Emphasis on Medical Management
Lende, M., & Rijhsinghani, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17249573 · Cited by 240 · see citing works
Evolution of Gestational Diabetes Mellitus across Continents in 21st Century
Dłuski, D. F., Ruszała, M., Rudziński, G., Pożarowska, K., Brzuszkiewicz, K., & Leszczyńska-Gorzelak, B. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192315804 · Cited by 41 · see citing works
Diagnosis of gestational diabetes: Evidence and pitfalls
Wong, T., Immanuel, J., Wong, V. W., Barnes, R., & Simmons, D. (2025) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2025.102069 · Cited by 4 · see citing works
- Authors
- O'Sullivan, J. B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1961-05-25
- Volume
- 264
- Issue
- 21
- Pages
- 1082-1085
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2005200514
- Cited by
- 100
- References
- 0
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 5 · 2014: 5 · 2013: 3 · 2012: 2
- FWCI
- 11.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- gestational diabetes mellitus, prediabetes, latent diabetes, diagnostic criteria, glucose tolerance, diabetogenic effect, spontaneous regression, pregnancy complications
- MeSH terms
- Diabetes Mellitus, Female, Humans, Pregnancy, Pregnancy Complications, Diabetes, Gestational
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