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Controlled Studies of Streptococcal Pharyngitis in a Pediatric Population: Factors Related to the Attack Rate of Rheumatic Fever
Abstract
PROMPT and adequate penicillin therapy of A pharyngitis due to Group A streptococci has proved effective in preventing primary attacks of rheumatic fever in military populations.1 , 2 Such treatment has been widely recommended for the control of rheumatic fever in the civilian population as well.3 The attack rate of rheumatic fever after such infections has been determined primarily from studies of epidemic, exudative pharyngitis or scarlet fever.4 5 6 Approximately 3 per cent of these infections have been followed by rheumatic fever.7 Within a given population, however, this rate has varied directly with the degree of the host's immune response to streptococcal disease. . . .
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Citations
Cited by
Pathogenesis of Group A Streptococcal Infections
Cunningham, M. W. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.3.470 · Cited by 2,261
Open randomised trial of prescribing strategies in managing sore throat
Little, P., Williamson, I., Warner, G., Gould, C., Gantley, M., & Kinmonth, A. L. (1997) · BMJ · doi:10.1136/bmj.314.7082.722 · Cited by 364
Diagnosis and Management of Group A Streptococcal Pharyngitis: A Practice Guideline
Bisno, A. L., Gerber, M. A., Kaplan, J. M. G., & Schwartz, R. H. (1997) · Clinical Infectious Diseases · doi:10.1086/513768 · Cited by 316
Principles of Appropriate Antibiotic Use for Acute Pharyngitis in Adults: Background
Cooper, R. J., Hoffman, J. R., Bartlett, J. G., Besser, R. E., Gonzales, R., Hickner, J. M., & Sande, M. A. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-6-200103200-00019 · Cited by 287
Evaluating diagnostic tests with imperfect standards
Valenstein, P. N. (1990) · American Journal of Clinical Pathology · doi:10.1093/ajcp/93.2.252 · Cited by 220
Metadata
- Authors
- Siegel, A. C., Johnson, E. E., & Stollerman, G. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1961-09-21
- Volume
- 265
- Issue
- 12
- Pages
- 559-566
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2320938607
- Cited by
- 221
- References
- 0
- FWCI
- 34.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Controlled Studies of Streptococcal Pharyngitis in a Pediatric Population: Factors Related to the Attack Rate of Rheumatic Fever. https://app.cochat.ai/papers/10.1056/nejm196109212651201
- The paper
- Siegel, A. C., Johnson, E. E., & Stollerman, G. H. (1961). Controlled Studies of Streptococcal Pharyngitis in a Pediatric Population: Factors Related to the Attack Rate of Rheumatic Fever. New England Journal of Medicine. https://doi.org/10.1056/nejm196109212651201
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
